SNP information rs10483727

Research and publications:

  20548946   A genome-wide association study of optic disc parameters.

  21398277   Genetic variants associated with optic nerve vertical cup-to-disc ratio are risk factors for primary open angle glaucoma in a US Caucasian population.

  22570617   Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma.

  22584021   Association between genetic variants associated with vertical cup-to-disc ratio and phenotypic features of primary open-angle glaucoma.

  22605921   Genome-wide association study of primary open angle glaucoma risk and quantitative traits.

  22761751   CDKN2B polymorphism is associated with primary open-angle glaucoma (POAG) in the Afro-Caribbean population of Barbados, West Indies.

  22840486   Genetic investigation into the endophenotypic status of central corneal thickness and optic disc parameters in relation to open-angle glaucoma.

  23963167   Investigation of known genetic risk factors for primary open angle glaucoma in two populations of African ancestry.

  24002674   Genome-wide association study and meta-analysis of intraocular pressure.

  24875647   Discovery and functional annotation of SIX6 variants in primary open-angle glaucoma.

  25027321   Genome-wide association and admixture analysis of glaucoma from the Women's Health Initiative.

  25097799   Developments in Ocular Genetics: 2013 Annual Review.

  25173105   Common variants near ABCA1, AFAP1 and GMDS confer risk of primary open-angle glaucoma.

  25242315   Association of open-angle glaucoma loci with incident glaucoma in the Blue Mountains Eye Study.

  25489222   Association of known common genetic variants with primary open angle, primary angle closure, and pseudoexfoliation glaucoma in Pakistani cohorts.

  25525164   Exome array analysis identifies CAV1/CAV2 as a susceptibility locus for intraocular pressure.

  25537207   Association of common SIX6 polymorphisms with peripapillary retinal nerve fiber layer thickness: the Singapore Chinese Eye Study.

  25711633   Genetic Variants Associated With Different Risks for High Tension Glaucoma and Normal Tension Glaucoma in a Chinese Population.

  25798827   Genetic association of SNPs near ATOH7, CARD10, CDKN2B, CDC7 and SIX1/SIX6 with the endophenotypes of primary open angle glaucoma in Indian population.

  25849520   Quantitative Trait Locus Analysis of SIX1-SIX6 With Retinal Nerve Fiber Layer Thickness in Individuals of European Descent.

  26690118   An Updated Review on the Genetics of Primary Open Angle Glaucoma.

  27260188   Association of three single nucleotide polymorphisms at the SIX1-SIX6 locus with primary open angle glaucoma in the Chinese population.

  27707548   Glaucoma Risk Alleles in the Ocular Hypertension Treatment Study.

  28347358   Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits.

  28499933   Major review: Molecular genetics of primary open-angle glaucoma.

  28663559   Association of SIX1/SIX6 locus polymorphisms with regional circumpapillary retinal nerve fibre layer thickness: The Nagahama study.

  28717659   Identification and characterization of variants and a novel 4 bp deletion in the regulatory region of SIX6, a risk factor for primary open-angle glaucoma.

  28721823   Genetic Risk Factors for Glaucoma and Exfoliation Syndrome Identified by Genome-wide Association Studies.

  29190129   Polymorphism rs10483727 in the SIX1/SIX6 Gene Locus Is a Risk Factor for Primary Open Angle Glaucoma in a Saudi Cohort.

  29261660   Genetic analysis of Japanese primary open-angle glaucoma patients and clinical characterization of risk alleles near CDKN2B-AS1, SIX6 and GAS7.

  29891935   A multiethnic genome-wide association study of primary open-angle glaucoma identifies novel risk loci.

  30005032   A Common Glaucoma-risk Variant of SIX6 Alters Retinal Nerve Fiber Layer and Optic Disc Measures in a European Population: The EPIC-Norfolk Eye Study.

  30127590   Analysis of CYP1B1 sequence alterations in patients with primary open-angle glaucoma of Saudi origin.

  30317457   Genome-wide association study of primary open-angle glaucoma in continental and admixed African populations.

  30405695   Lack of Association of rs1192415 in TGFBR3-CDC7 With Visual Field Progression: A Cohort Study in Chinese Open Angle Glaucoma Patients.

  30519491   Lack of Association between Variant rs7916697 in ATOH7 and Primary Open Angle Glaucoma in a Saudi Cohort.

  30586556   Association of the SIX6 locus with primary open angle glaucoma in southern Chinese and Japanese.

  31284308   Association of Polymorphisms at the SIX1-SIX6 Locus With Primary Open-Angle Glaucoma.

  31337432   Polymorphisms rs693421 and rs2499601 at locus 1q43 and their haplotypes are not associated with primary open-angle glaucoma: a case-control study.

  31436842   Association of a Primary Open-Angle Glaucoma Genetic Risk Score With Earlier Age at Diagnosis.

  31632126   Genetic Analysis Of ABCA1 Gene Of Primary Glaucoma In Jordanian Arab Population.

  31914149   Association of endothelial nitric oxide synthase (NOS3) gene polymorphisms with primary open-angle glaucoma in a Saudi cohort.

  32545285   The Genetic and Endoplasmic Reticulum-Mediated Molecular Mechanisms of Primary Open-Angle Glaucoma.

  32719476   Age-dependent regional retinal nerve fibre changes in SIX1/SIX6 polymorphism.

  32821913   Association of Glaucoma Risk Genes with Retinal Nerve Fiber Layer in a Multi-ethnic Asian Population: The Singapore Epidemiology of Eye Diseases Study.

  32933932   Genetic analysis of primary open-angle glaucoma-related risk alleles in a Korean population: the GLAU-GENDISK study.

  33396423   Molecular Genetics of Glaucoma: Subtype and Ethnicity Considerations.

  33553411   Coinheritance of OLFM2 and SIX6 variants in a Chinese family with juvenile-onset primary open-angle glaucoma: A case report.

  33605984   The Role of Genetic Ancestry as a Risk Factor for Primary Open-angle Glaucoma in African Americans.

  33726755   Analysis of risk allele frequencies of single nucleotide polymorphisms related to open-angle glaucoma in different ethnic groups.

  34840687   Prevalence Rates and Risk Factors for Primary Open Angle Glaucoma in the Middle East.

  35017159   Association of SIX1-SIX6 polymorphisms with peripapillary retinal nerve fibre layer thickness in children.

  35566612   Asian Race and Primary Open-Angle Glaucoma: Where Do We Stand?

  35658088   Association of Polymorphisms at the SIX1/SIX6 Locus With Normal Tension Glaucoma in a Korean Population.