SNP information rs999737

Research and publications:

  19330030   A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1).

  20085711   Leveraging genetic variability across populations for the identification of causal variants.

  20095854   Novel breast cancer risk alleles and interaction with ionizing radiation among U.S. radiologic technologists.

  20146796   Familial relative risks for breast cancer by pathological subtype: a population-based cohort study.

  20237344   Performance of common genetic variants in breast-cancer risk models.

  20418484   Common variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriers.

  20453838   Genome-wide association study identifies five new breast cancer susceptibility loci.

  20496165   Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk.

  20585100   Genome-wide association studies of cancer.

  20699374   Evaluation of breast cancer susceptibility loci in Chinese women.

  20957429   Discriminatory accuracy and potential clinical utility of genomic profiling for breast cancer risk in BRCA-negative women.

  21102626   Caution in generalizing known genetic risk markers for breast cancer across all ethnic/racial populations.

  21219822   [Recent progress in genetic variants associated with cancer and their implications in diagnostics development].

  21468051   Polygenic susceptibility to prostate and breast cancer: implications for personalised screening.

  21514219   Genetic variants associated with breast-cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence

  21593217   Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers.

  21791674   Interactions between genetic variants and breast cancer risk factors in the breast and prostate cancer cohort consortium.

  21795501   Replication of GWAS breast cancer susceptibility loci in the Women's Health Initiative African American SHARe Study.

  21844186   Common breast cancer susceptibility loci are associated with triple-negative breast cancer.

  21852243   Fine-mapping of breast cancer susceptibility loci characterizes genetic risk in African Americans.

  21852249   Associations of common variants at 1p11.2 and 14q24.1 (RAD51L1) with breast cancer risk and heterogeneity by tumor subtype: findings from the Breast Cancer Association Consortium.

  21869864   An integrative genomics approach to biomarker discovery in breast cancer.

  21959381   Fine mapping of 14q24.1 breast cancer susceptibility locus.

  22053997   Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2.

  22232737   Novel genetic markers of breast cancer survival identified by a genome-wide association study.

  22313133   Genetic variants at 14q24.1 and breast cancer susceptibility: a fine-mapping study in Chinese women.

  22314178   Breast cancer risk prediction and individualised screening based on common genetic variation and breast density measurement.

  22357627   Evaluation of 19 susceptibility loci of breast cancer in women of African ancestry.

  22433456   Reproductive aging-associated common genetic variants and the risk of breast cancer.

  22452962   A genome-wide association study identifies a breast cancer risk variant in ERBB4 at 2q34: results from the Seoul Breast Cancer Study.

  22454379   Common breast cancer susceptibility variants in LSP1 and RAD51L1 are associated with mammographic density measures that predict breast cancer risk.

  22747683   Genetic variants associated with breast size also influence breast cancer risk.

  22792358   Association between genetic variants in DNA and histone methylation and telomere length.

  22806168   A multistage genetic association study identifies breast cancer risk loci at 10q25 and 16q24.

  22972951   Prediction of breast cancer risk by genetic risk factors, overall and by hormone receptor status.

  23136140   Genetic susceptibility loci for subtypes of breast cancer in an African American population.

  23221726   Gene-environment interactions for breast cancer risk among Chinese women: a report from the Shanghai Breast Cancer Genetics Study.

  23474973   Incremental impact of breast cancer SNP panel on risk classification in a screening population of white and African American women.

  23535729   Large-scale genotyping identifies 41 new loci associated with breast cancer risk.

  23535825   Common genetic determinants of breast-cancer risk in East Asian women: a collaborative study of 23 637 breast cancer cases and 25 579 controls.

  23536562   Genetic susceptibility to triple-negative breast cancer.

  23544014   Evidence of gene-environment interactions between common breast cancer susceptibility loci and established environmental risk factors.

  23593120   Evaluating genome-wide association study-identified breast cancer risk variants in African-American women.

  23635555   The relationship between eight GWAS-identified single-nucleotide polymorphisms and primary breast cancer outcomes.

  24025454   Hereditary breast cancer: ever more pieces to the polygenic puzzle.

  24062231   DNA double-strand break repair genotype and phenotype and breast cancer risk within sisters from the New York site of the Breast Cancer Family Registry (BCFR).

  24266904   Breast cancer prediction using genome wide single nucleotide polymorphism data.

  24359602   Common breast cancer risk variants in the post-COGS era: a comprehensive review.

  24373701   Breast cancer susceptibility loci in association with age at menarche, age at natural menopause and the reproductive lifespan.

  24510657   Evaluating 17 breast cancer susceptibility loci in the Nashville breast health study.

  24729084   Analyzing 395,793 samples shows significant association between rs999737 polymorphism and breast cancer.

  24771903   Breast Cancer Risk - From Genetics to Molecular Understanding of Pathogenesis.

  24875630   Validation of six genetic determinants of susceptibility to estrogen-induced mammary cancer in the rat and assessment of their relevance to breast cancer risk in humans.

  24895409   Post-GWAS gene-environment interplay in breast cancer: results from the Breast and Prostate Cancer Cohort Consortium and a meta-analysis on 79,000 women.

  24941967   Breast cancer risk assessment using genetic variants and risk factors in a Singapore Chinese population.

  25255808   Additive interactions between susceptibility single-nucleotide polymorphisms identified in genome-wide association studies and breast cancer risk factors in the Breast and Prostate Cancer Cohort Consortium.

  25567532   The use of the Gail model, body mass index and SNPs to predict breast cancer among women with abnormal (BI-RADS 4) mammograms.

  25611573   Association of breast cancer risk loci with breast cancer survival.

  25862352   Novel Associations between Common Breast Cancer Susceptibility Variants and Risk-Predicting Mammographic Density Measures.

  25881232   Associations between breast density and a panel of single nucleotide polymorphisms linked to breast cancer risk: a cohort study with digital mammography.

  26070784   Genetic risk variants associated with in situ breast cancer.

  26175953   FGFR2 gene polymorphisms are associated with breast cancer risk in the Han Chinese population.

  26472073   Multiple breast cancer risk variants are associated with differential transcript isoform expression in tumors.

  26510858   Patients with a High Polygenic Risk of Breast Cancer do not have An Increased Risk of Radiotherapy Toxicity.

  26802016   Interactions between breast cancer susceptibility loci and menopausal hormone therapy in relationship to breast cancer in the Breast and Prostate Cancer Cohort Consortium.

  27149063   RAD51B in Familial Breast Cancer.

  27392074   The Relationship between Common Genetic Markers of Breast Cancer Risk and Chemotherapy-Induced Toxicity: A Case-Control Study.

  27814745   Deep targeted sequencing of 12 breast cancer susceptibility regions in 4611 women across four different ethnicities.

  27848153   Previous GWAS hits in relation to young-onset breast cancer.

  28098224   Association of Genome-Wide Association Study (GWAS) Identified SNPs and Risk of Breast Cancer in an Indian Population.

  28152060   Expression Quantitative Trait loci (QTL) in tumor adjacent normal breast tissue and breast tumor tissue.

  29255180   Contribution of germline deleterious variants in the RAD51 paralogs to breast and ovarian cancers.

  29382703   Common Genetic Variation and Breast Cancer Risk-Past, Present, and Future.

  29445177   Validating a breast cancer score in Spanish women. The MCC-Spain study.

  31125336   Evaluation of significant genome-wide association studies risk - SNPs in young breast cancer patients.

  32269954   Copy number alternations of the 17q23-rs6504950 locus are associated with advanced breast cancers in Taiwanese women.

  32287273   DOT: Gene-set analysis by combining decorrelated association statistics.