SNP information rs855791

Research and publications:

  19820698   Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels.

  19820699   Common variants in TMPRSS6 are associated with iron status and erythrocyte volume.

  19862010   Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.

  19880490   A genome-wide association analysis of serum iron concentrations.

  20858683   Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.

  20927387   A genome-wide association study of red blood cell traits using the electronic medical record.

  21115529   Genetics and genomics of human ageing.

  21149283   Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels.

  21208937   Identification of a common variant in the TFR2 gene implicated in the physiological regulation of serum iron levels.

  21483845   Genome-wide association study identifies genetic loci associated with iron deficiency.

  21785125   Association of HFE and TMPRSS6 genetic variants with iron and erythrocyte parameters is only in part dependent on serum hepcidin concentrations.

  21873547   TMPRSS6 rs855791 modulates hepcidin transcription in vitro and serum hepcidin levels in normal individuals.

  21975967   Genetic determinants of variability in glycated hemoglobin (HbA(1c)) in humans: review of recent progress and prospects for use in diabetes care

  21978626   Four variants in transferrin and HFE genes as potential markers of iron deficiency anaemia risk: an association study in menstruating women.

  22301935   Association of TMPRSS6 polymorphisms with ferritin, hemoglobin, and type 2 diabetes risk in a Chinese Han population.

  22323359   TMPRSS6, but not TF, TFR2 or BMP2 variants are associated with increased risk of iron-deficiency anemia.

  22509377   Candidate gene sequencing of SLC11A2 and TMPRSS6 in a family with severe anaemia: common SNPs, rare haplotypes, no causative mutation.

  22540250   Race-ethnic differences in the association of genetic loci with HbA1c levels and mortality in U.S. adults: the third National Health and Nutrition Examination Survey (NHANES III).

  22815867   Genetic determinants for body iron store and type 2 diabetes risk in US men and women.

  22885719   Effect of the A736V TMPRSS6 polymorphism on the penetrance and clinical expression of hereditary hemochromatosis.

  23092954   SHAVE: shrinkage estimator measured for multiple visits increases power in GWAS of quantitative traits

  23794717   Associations of common variants in HFE and TMPRSS6 with iron parameters are independent of serum hepcidin in a general population: a replication study.

  24801367   A candidate gene approach for identifying differential iron responses in young overweight women to an energy-restricted haem iron-rich diet.

  24966834   The role of TMPRSS6/matriptase-2 in iron regulation and anemia.

  25416640   Inter-ethnic differences in genetic variants within the transmembrane protease, serine 6 (TMPRSS6) gene associated with iron status indicators: a systematic review with meta-analyses.

  25741868   Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology.

  26159428   Iron and hepcidin as risk factors in atherosclerosis: what do the genes say?

  26263361   About TMPRSS6 rs855791 polymorphism, iron metabolism and celiac disease.

  26446360   Mendelian randomization studies of biomarkers and type 2 diabetes.

  26582562   Signatures of Evolutionary Adaptation in Quantitative Trait Loci Influencing Trace Element Homeostasis in Liver.

  26597663   Genetic factors influencing ferritin levels in 14,126 blood donors: results from the Danish Blood Donor Study.

  26648684   Update on genetics and diabetic retinopathy.

  26695521   Is Mendelian Randomization the Key to Understanding Causal Aspects of Parkinson's Disease?

  26746433   Multiple sclerosis-like diagnosis as a complication of previously treated malaria in an iron and vitamin D deficient Nigerian patient.

  27280446   Replication and Characterization of Association between ABO SNPs and Red Blood Cell Traits by Meta-Analysis in Europeans.

  27437086   Allele Frequencies of the Single Nucleotide Polymorphisms Related to the Body Burden of Heavy Metals in the Korean Population and Their Ethnic Differences.

  27846281   Meta-GWAS and Meta-Analysis of Exome Array Studies Do Not Reveal Genetic Determinants of Serum Hepcidin.

  28684612   The Effect of Iron Status on Risk of Coronary Artery Disease: A Mendelian Randomization Study-Brief Report.

  28820869   Necrotizing enterocolitis and high intestinal iron uptake due to genetic variants.

  29167213   Interaction of Dietary and Genetic Factors Influencing Body Iron Status and Risk of Type 2 Diabetes Within the EPIC-InterAct Study.

  29928945   The role of TMPRSS6 gene variants in iron-related hematological parameters in Turkish patients with iron deficiency anemia.

  30111473   Association of FokI rs2228570 and TMPRSS6 rs855791 polymorphisms with cow's milk protein allergy in children.

  30536387   Genetic factors influencing hemoglobin levels in 15,567 blood donors: results from the Danish Blood Donor Study.

  30593316   [Association between the polymorphisms of TMPRSS6 and the levels of serum ferrtin and soluble transferrin receptor in pregnant women in Lüliang Area of Shanxi Province].

  30911357   TMPRSS6 rs855791 polymorphism and susceptibility to iron deficiency anaemia in non-dialysis chronic kidney disease patients in South Africa.

  31010126   The Association of TMPRSS6 Gene Polymorphism and Iron Intake with Iron Status among Under-Two-Year-Old Children in Lombok, Indonesia.

  31097152   Associations between single nucleotide polymorphisms and erythrocyte parameters in humans: A systematic literature review.

  31194788   GWAS and PheWAS of red blood cell components in a Northern Nevadan cohort.

  31220083   Associations of genetically determined iron status across the phenome: A mendelian randomization study.

  31226389   Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration.

  32363518   Associations of TMPRSS6 Polymorphisms with Gestational Diabetes Mellitus in Chinese Han Pregnant Women: a Preliminary Cohort Study.

  32385772   An investigation of the relationship between TMPRSS6 gene expression, genetic variants and clinical findings in breast cancer.

  32422234   Study the association of transmembrane serine protease 6 gene polymorphisms with iron deficiency status in Saudi Arabia.

  33054130   The TMPRSS6 variant (SNP rs855791) affects iron metabolism and oral iron absorption - a stable iron isotope study in Taiwanese women.

  33193643   A Family Affected by a Life-Threatening Erythrocyte Defect Caused by Pyruvate Kinase Deficiency With Normal Iron Status: A Case Report.

  33272965   Ziltivekimab for Treatment of Anemia of Inflammation in Patients on Hemodialysis: Results from a Phase 1/2 Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial.

  33367529   Molecular analysis of homeostatic iron regulator, transmembrane protease serine-6, and BTB domain-containing protein-9 variants and iron parameters in blood donors.

  33424363   Role of TMPRSS6 rs855791 (T > C) polymorphism in reproductive age women with iron deficiency anemia from Lahore, Pakistan.

  33817543   Common Variants in the TMPRSS6 Gene Alter Hepcidin but not Plasma Iron in Response to Oral Iron in Healthy Gambian Adults: A Recall-by-Genotype Study.

  33850216   Association of common TMPRSS6 and TF gene variants with hepcidin and iron status in healthy rural Gambians.

  34085096   Dietary iron to total energy intake ratio and type 2 diabetes incidence in a longitudinal 12-year analysis of the Korean Genome and Epidemiology Cohort Study.

  34104963   Assessing the impact of alcohol consumption on the genetic contribution to mean corpuscular volume.

  34444942   TMPRSS6 rs855791 Polymorphism Status in Children with Celiac Disease and Anemia.

  34488438   Epidemiologic and Genetic Associations of Erythropoietin With Blood Pressure, Hypertension, and Coronary Artery Disease.

  34790739   Association between serum iron status and primary liver cancer risk: a Mendelian randomization analysis.

  35052344   Genotype Score for Iron Status Is Associated with Muscle Fiber Composition in Women.

  35124268   Mendelian Randomization Analysis Reveals No Causal Relationship Between Nonalcoholic Fatty Liver Disease and Severe COVID-19.

  35811987   Causal Relationship of Genetically Predicted Serum Micronutrients Levels With Sarcopenia: A Mendelian Randomization Study.

  36014764   Appraising the Causal Association between Systemic Iron Status and Heart Failure Risk: A Mendelian Randomisation Study.