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SNP information rs8170


Normal allele: GG

Polymorphism rs8170 is related to topics like this:

BRCA gene

BRCA stands for "BReast CAncer gene" and refers to two distinct genes, BRCA1 and BRCA2, which have...

Research and publications:

  18650832   MAST3: a novel IBD risk factor that modulates TLR4 signaling.

  19572197   Mutation screening of the MERIT40 gene encoding a novel BRCA1 and RAP80 interacting protein in breast cancer families.

  20456938   The inherited genetics of ovarian and endometrial cancer.

  20852631   A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population.

  20852633   Common variants at 19p13 are associated with susceptibility to ovarian cancer.

  21431873   Germline mutational analysis of the C19orf62 gene in African-American women with breast cancer.

  21774837   Mutation screening of the RNF8, UBC13 and MMS2 genes in Northern Finnish breast cancer families.

  21799032   Modification of BRCA1-Associated Breast and Ovarian Cancer Risk by BRCA1-Interacting Genes.

  21844186   Common breast cancer susceptibility loci are associated with triple-negative breast cancer.

  22235027   Evaluation of microRNA expression profiles and their associations with risk alleles in lymphoblastoid cell lines of familial ovarian cancer.

  22253144   Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers.

  22331459   19p13.1 is a triple-negative-specific breast cancer susceptibility locus.

  22351618   Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers.

  22357627   Evaluation of 19 susceptibility loci of breast cancer in women of African ancestry.

  23136140   Genetic susceptibility loci for subtypes of breast cancer in an African American population.

  23535729   Large-scale genotyping identifies 41 new loci associated with breast cancer risk.

  23535825   Common genetic determinants of breast-cancer risk in East Asian women: a collaborative study of 23 637 breast cancer cases and 25 579 controls.

  23536562   Genetic susceptibility to triple-negative breast cancer.

  23593120   Evaluating genome-wide association study-identified breast cancer risk variants in African-American women.

  24025454   Hereditary breast cancer: ever more pieces to the polygenic puzzle.

  24244489   A common variant in the SIAH2 locus is associated with estrogen receptor-positive breast cancer in the Chinese Han population.

  24359602   Common breast cancer risk variants in the post-COGS era: a comprehensive review.

  24510657   Evaluating 17 breast cancer susceptibility loci in the Nashville breast health study.

  24771903   Breast Cancer Risk - From Genetics to Molecular Understanding of Pathogenesis.

  24886216   Functional annotation signatures of disease susceptibility loci improve SNP association analysis.

  24895409   Post-GWAS gene-environment interplay in breast cancer: results from the Breast and Prostate Cancer Cohort Consortium and a meta-analysis on 79,000 women.

  24941967   Breast cancer risk assessment using genetic variants and risk factors in a Singapore Chinese population.

  25057183   A robust association test for detecting genetic variants with heterogeneous effects.

  25253900   Breast Cancer Risk - Genes, Environment and Clinics.

  25255808   Additive interactions between susceptibility single-nucleotide polymorphisms identified in genome-wide association studies and breast cancer risk factors in the Breast and Prostate Cancer Cohort Consortium.

  25611573   Association of breast cancer risk loci with breast cancer survival.

  26070784   Genetic risk variants associated with in situ breast cancer.

  26231170   Loss of heterozygosity: what is it good for?

  26472073   Multiple breast cancer risk variants are associated with differential transcript isoform expression in tumors.

  26510858   Patients with a High Polygenic Risk of Breast Cancer do not have An Increased Risk of Radiotherapy Toxicity.

  26747452   Investigation of Exomic Variants Associated with Overall Survival in Ovarian Cancer.

  26848770   Genetic evaluation of BRCA1 associated a complex genes with triple-negative breast cancer susceptibility in Chinese women.

  26884359   Genetic predisposition to ductal carcinoma in situ of the breast.

  27117709   Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer.

  27392074   The Relationship between Common Genetic Markers of Breast Cancer Risk and Chemotherapy-Induced Toxicity: A Case-Control Study.

  27432226   Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types.

  27471560   Genomic/Epigenomic Alterations in Ovarian Carcinoma: Translational Insight into Clinical Practice.

  27601076   Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus.

  27814745   Deep targeted sequencing of 12 breast cancer susceptibility regions in 4611 women across four different ethnicities.

  27825120   Trans-ethnic follow-up of breast cancer GWAS hits using the preferential linkage disequilibrium approach.

  28098224   Association of Genome-Wide Association Study (GWAS) Identified SNPs and Risk of Breast Cancer in an Indian Population.

  31125336   Evaluation of significant genome-wide association studies risk - SNPs in young breast cancer patients.

  32823908   Critical Analysis of Genome-Wide Association Studies: Triple Negative Breast Cancer Quae Exempli Causa.

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