Normal allele: AA
Genetic variation associated with iron overload, chronic anaemia and motor neurone disease.
Polymorphism rs7385804 is related to topics like this:
Research and publications:
19820697 A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.
19862010 Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium.
21153663 Genetic association analysis highlights new loci that modulate hematological trait variation in Caucasians and African Americans.
21208937 Identification of a common variant in the TFR2 gene implicated in the physiological regulation of serum iron levels.
22323359 TMPRSS6, but not TF, TFR2 or BMP2 variants are associated with increased risk of iron-deficiency anemia.
23751596 Association between genetic variations in TFR2 gene and coronary heart disease in Chinese: a case-control study.
26159428 Iron and hepcidin as risk factors in atherosclerosis: what do the genes say?
27332551 Associations between Common Variants in Iron-Related Genes with Haematological Traits in Populations of African Ancestry.
31936202 The Prevalence of Insomnia and the Link between Iron Metabolism Genes Polymorphisms, TF rs1049296 C>T, TF rs3811647 G>A, TFR rs7385804 A>C, HAMP rs10421768 A>G and Sleep Disorders in Polish Individuals with ASD.
32895881 The Proteomics Study of Compounded HFE/TF/TfR2/HJV Genetic Variations in a Thai Family with Iron Overload, Chronic Anemia, and Motor Neuron Disorder.
35682458 Hepcidin (rs10421768), Transferrin (rs3811647, rs1049296) and Transferrin Receptor 2 (rs7385804) Gene Polymorphism Might Be Associated with the Origin of Multiple Sclerosis.