SNP information rs6908425

Research and publications:

  18587394   Genome-wide association identifies more than 30 different susceptibility loci for Crohn's disease.

  18923449   Further genetic evidence for three psoriasis-risk genes: ADAM33, CDKAL1, and PTPN22

  19068216   Investigation of Crohn's disease risk loci in ulcerative colitis further determines their molecular relatedness.

  19422935   Genetic risk profiling and disease progression prediction in patients with Crohn's disease.

  19474294   Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

  19587699   Differential contribution of CDKAL1 variants to the development of psoriasis, Crohn's disease and type II diabetes.

  19638187   Genetic susceptibility to psoriasis: an emerging picture.

  19915572   Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region.

  20014019   Genome wide association (GWA) predictors of anti-TNFalpha therapeutic responsiveness in pediatric inflammatory bowel disease.

  20228799   Genome-wide association identifies multiple ulcerative colitis susceptibility loci.

  20518082   Role of genetics in prediction of disease course and response to therapy.

  20570966   Nonsecretory fucosyltransferase 2 (FUT2) status is associated with Crohn's disease.

  20805105   Synthetic associations in the context of genome-wide association scan signals

  21102463   Genome-wide meta-analysis increases the number of confirmed susceptibility loci for Crohn's disease to 71.

  21152001   The association of 1q32 and STAT3 variants with ankylosing spondylitis suggests genetic overlap with Crohn's disease.

  21297633   Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47.

  21304977   An investigation of genome-wide studies reported susceptibility loci for ulcerative colitis shows limited replication in north Indians.

  21559375   A genetic risk score combining ten psoriasis risk loci improves disease prediction.

  21730793   The influence of risk alleles for Crohn's disease and smoking on the location of the disease.

  21752155   Genetic susceptibility to inflammation and colonic transit in lower functional gastrointestinal disorders: preliminary analysis.

  22219593   The role of genetics in the diagnosis and prognosis of Crohn's disease.

  22253516   The role of genetics in the diagnosis and prognosis of Crohn's disease.

  22770979   Presence of multiple independent effects in risk loci of common complex human diseases.

  23028907   Limited evidence for parent-of-origin effects in inflammatory bowel disease associated loci.

  23300620   Genotype/phenotype analysis of 53 genetic polymorphisms associated with Crohn's disease.

  25061809   Analyzing genome-wide association studies with an FDR controlling modification of the Bayesian Information Criterion.

  26563541   CDKAL1 gene variants affect the anti-TNF response among Psoriasis patients.

  26613086   Polymorphisms Associated with Age at Onset in Patients with Moderate-to-Severe Plaque Psoriasis.

  27073425   Candidate gene polymorphisms and risk of psoriasis: A pilot study.

  27667907   Partial linear varying multi-index coefficient model for integrative gene-environment interactions.

  27936930   Different Contributions of CDKAL1, KIF21B, and LRRK2/MUC19 Polymorphisms to SAPHO Syndrome, Rheumatoid Arthritis, Ankylosing Spondylitis, and Seronegative Spondyloarthropathy.

  28617847   The association between 38 previously reported polymorphisms and psoriasis in a Polish population: High predicative accuracy of a genetic risk score combining 16 loci.

  29967744   Association of Crohn's disease-associated chromosome 1q32 with ankylosing spondylitis is independent of bowel symptoms and fecal calprotectin.