Normal allele: TT
The rs5361 Ser128Arg variant in this gene, known as E-selectin, is associated with several thrombotic disorders. Homozygous carriers of rs5361(CC) have a 4-fold higher risk of recurrent venous thromboembolism
Polymorphism rs5361 is related to topics like this:
Research and publications:
15726497 Gene-environment interaction effects on the development of immune responses in the 1st year of life
17327408 Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival
19066394 Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma
19559392 A candidate gene association study of 77 polymorphisms in migraine
20691427 Genetic associations of brain structural networks in schizophrenia: a preliminary study
21521525 Evaluation of variants in the selectin genes in age-related macular degeneration.
22113576 Polymorphisms in immune function genes and non-Hodgkin lymphoma survival.
22414298 Lack of an association between E-selectin gene polymorphisms and risk of Kawasaki disease.
22589243 Association of E-selectin gene polymorphisms with ischemic stroke in a Chinese Han population.
23274712 Genetic polymorphisms and the risk of myocardial infarction in patients under 45 years of age.
23772946 Association of cell adhesion molecule gene polymorphisms with recurrent aphthous stomatitis.
25294155 A comprehensive evaluation of the role of genetic variation in follicular lymphoma survival.