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SNP information rs5361

Normal allele: TT

The rs5361 Ser128Arg variant in this gene, known as E-selectin, is associated with several thrombotic disorders. Homozygous carriers of rs5361(CC) have a 4-fold higher risk of recurrent venous thromboembolism

Polymorphism rs5361 is related to topics like this:

Thrombosis


Research and publications:

  15726497   Gene-environment interaction effects on the development of immune responses in the 1st year of life

  16820586   Inflammatory gene polymorphisms and risk of postoperative myocardial infarction after cardiac surgery

  17327408   Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival

  18513389   New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background

  18633131   Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era

  19066394   Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma

  19131662   A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients

  19263529   Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach

  19330901   Association of 77 polymorphisms in 52 candidate genes with blood pressure progression and incident hypertension: the Women's Genome Health Study

  19559392   A candidate gene association study of 77 polymorphisms in migraine

  20622166   Combined effect of inflammatory gene polymorphisms and the risk of ischemic stroke in a prospective cohort of subjects with type 2 diabetes: a Go-DARTS study.

  20691427   Genetic associations of brain structural networks in schizophrenia: a preliminary study

  21521525   Evaluation of variants in the selectin genes in age-related macular degeneration.

  21629188   Low frequency haplotypes of E-selectin polymorphisms G2692A and C1901T give increased protection from coronary artery disease.

  21780194   E-selectin rs5361 and FCGR2A rs1801274 variants were associated with increased risk of gastric cancer in a Chinese population.

  21881522   Association of ATP1B1, RGS5 and SELE polymorphisms with hypertension and blood pressure in African-Americans.

  22113576   Polymorphisms in immune function genes and non-Hodgkin lymphoma survival.

  22116284   A two-step genetic study on quantitative precursors of coronary artery disease in a homogeneous Indian population: case-control association discovery and validation by transmission-disequilibrium test.

  22388798   Gene panels to help identify subgroups at high and low risk of coronary heart disease among those randomized to antihypertensive treatment: the GenHAT study.

  22414298   Lack of an association between E-selectin gene polymorphisms and risk of Kawasaki disease.

  22589243   Association of E-selectin gene polymorphisms with ischemic stroke in a Chinese Han population.

  23190470   Association of SELE genotypes/haplotypes with sE-selectin levels in Taiwanese individuals: interactive effect of MMP9 level.

  23274712   Genetic polymorphisms and the risk of myocardial infarction in patients under 45 years of age.

  23533563   Novel risk factors for premature peripheral arterial occlusive disease in non-diabetic patients: a case-control study.

  23772946   Association of cell adhesion molecule gene polymorphisms with recurrent aphthous stomatitis.

  25091233   Association of F11 polymorphism rs2289252 with deep vein thrombosis and related phenotypes in population of Latvia.

  25147926   Cellular adhesion gene SELP is associated with rheumatoid arthritis and displays differential allelic expression.

  25294155   A comprehensive evaluation of the role of genetic variation in follicular lymphoma survival.

  26791477   The effects of genes implicated in cardiovascular disease on blood pressure response to treatment among treatment-naive hypertensive African Americans in the GenHAT study.

  27616475   Gene variants as risk factors for gastroschisis.

  28339009   Identification of EGFLAM, SPATC1L and RNASE13 as novel susceptibility loci for aortic aneurysm in Japanese individuals by exome-wide association studies.

  30501958   The rs1805193, rs5361, and rs5355 single nucleotide polymorphisms in the E-selectin gene (SEL-E) are associated with subclinical atherosclerosis: The Genetics of Atherosclerotic Disease (GEA) Mexican study.

  32241219   Association of E-Selectin gene rs5361 polymorphism with ischemic stroke susceptibility: a systematic review and Meta-analysis.

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