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SNP information rs4553808

Normal allele: AA

CTLA4 variants contribute to genetic predisposition to myasthenia gravis.

Polymorphism rs4553808 is related to topics like this:

Myasthenia


Research and publications:

  15452244   Cytotoxic T-lymphocyte antigen 4 gene and recovery from hepatitis B virus infection.

  17825114   Association of CTLA-4 gene polymorphisms with sporadic breast cancer in Chinese Han population.

  18528295   Influence of cytotoxic T lymphocyte-associated antigen 4 (CTLA4) common polymorphisms on outcome in treatment of melanoma patients with CTLA-4 blockade.

  19609446   CTLA4 autoimmunity-associated genotype contributes to severe pulmonary tuberculosis in an African population.

  19622768   CTLA4 variants, UV-induced tolerance, and risk of non-melanoma skin cancer.

  21228734   Genetic variation associated with bortezomib-induced peripheral neuropathy.

  21791469   Genetic factors underlying the risk of bortezomib induced peripheral neuropathy in multiple myeloma patients.

  22123319   A prospective phase II trial exploring the association between tumor microenvironment biomarkers and clinical activity of ipilimumab in advanced melanoma.

  22178694   Genetic variation in donor CTLA-4 regulatory region is a strong predictor of outcome after allogeneic hematopoietic cell transplantation for hematologic malignancies.

  22418270   Polymorphisms in cytotoxic T lymphocyte associated antigen-4 influence the rate of acute rejection after renal transplantation in 167 Chinese recipients.

  23261408   -1722T/C polymorphism (rs733618) of CTLA-4 significantly associated with systemic lupus erythematosus (SLE): a comprehensive meta-analysis.

  23300559   Polymorphisms in CTLA4 influence incidence of drug-induced liver injury after renal transplantation in Chinese recipients.

  23628397   Lack of association between CTLA-4 and PDCD1 polymorphisms and acute rejection in German liver transplant recipients.

  24631737   Cytotoxic T-lymphocyte antigen-4 single nucleotide polymorphisms are not associated with outcomes after unrelated donor transplantation: a center for international blood and marrow transplant research analysis.

  25003519   CTLA4 variants and haplotype contribute genetic susceptibility to myasthenia gravis in northern Chinese population.

  25356901   Cytotoxic T-lymphocyte antigen 4 gene polymorphism influences the incidence of symptomatic human cytomegalovirus infection after renal transplantation.

  25900029   SNP-SNP interactions of immunity related genes involved in the CD28/B7 pathway with susceptibility to invasive ductal carcinoma of the breast.

  26263974   Molecular Classification and Pharmacogenetics of Primary Plasma Cell Leukemia: An Initial Approach toward Precision Medicine.

  27081086   Effect of CTLA-4 gene polymorphisms on long-term kidney allograft function in Han Chinese recipients.

  27118383   CTLA-4 polymorphisms and haplotype correlate with survival in ALL after allogeneic stem cell transplantation from related HLA-haplotype-mismatched donor.

  27351445   Association of functional genetic variants of CTLA4 with reduced serum CTLA4 protein levels and increased risk of idiopathic recurrent miscarriages.

  27800130   The Association Between Viral Infections and Co-stimulatory Gene Polymorphisms in Kidney Transplant Outcomes.

  28097051   CTLA-4 polymorphisms associate with breast cancer susceptibility in Asians: a meta-analysis.

  28112181   IL-3 and CTLA4 gene polymorphisms may influence the tacrolimus dose requirement in Chinese kidney transplant recipients.

  29264740   CTLA-4 polymorphisms are associated with treatment outcomes of patients with multiple myeloma receiving bortezomib-based regimens.

  29335768   CTLA-4 polymorphisms: influence on transplant-related mortality and survival in children undergoing allogeneic hematopoietic stem cell transplantation.

  29794444   Association of Five Snps in Cytotoxic T-Lymphocyte Antigen 4 and Cancer Susceptibility: Evidence from 67 Studies.

  29968132   Cytotoxic T- Lymphocyte Antigen-4 (CTLA4) Gene Expression and Urinary CTLA4 Levels in Idiopathic Nephrotic Syndrome.

  30009380   Association of CTLA-4 polymorphisms with increased risks of myasthenia gravis.

  30334961   Correlation between CTLA4 genetic polymorphisms, its serum protein level and the susceptibility to recurrent spontaneous abortion: A case-control study.

  31766247   Association of CTLA4 Gene Polymorphism with Transfusion Reaction after Infusion of Leukoreduced Blood Component.

  32178688   CTLA-4 polymorphisms and predisposition to digestive system malignancies: a meta-analysis of 31 published studies.

  32745291   Th2 cell regulatory and effector molecules single nucleotide polymorphisms and periodontitis.

  33519815   Immune Checkpoint Molecules-Inherited Variations as Markers for Cancer Risk.

  33717091   Polymorphisms and Circulating Plasma Protein Levels of Immune Checkpoints (CTLA-4 and PD-1) Are Associated With Posner-Schlossman Syndrome in Southern Chinese.

  34008865   Genetic Polymorphisms of Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4) and clinical outcomes post-allogeneic hematopoietic stem cell transplantation: A systematic review and meta-analysis.

  34671352   The Association Between Single-Nucleotide Polymorphisms of Co-Stimulatory Genes Within Non-HLA Region and the Prognosis of Leukemia Patients With Hematopoietic Stem Cell Transplantation.

  35228813   Prediction of Tacrolimus Dose/Weight-Adjusted Trough Concentration in Pediatric Refractory Nephrotic Syndrome: A Machine Learning Approach.

  35998845   Role of Polymorphisms on the Recurrent Pregnancy Loss: A Systematic Review, Meta-analysis and Bioinformatic Analysis.

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