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SNP information rs41293521

RS41293521

Normal allele: TT

Polymorphism rs41293521 is related to topics like this:

BRCA gene

BRCA stands for "BReast CAncer gene" and refers to two distinct genes, BRCA1 and BRCA2, which have...


Research and publications:

  9150172   BRCA2 mutations in hereditary breast and ovarian cancer in France.

  10486320   The contribution of germline BRCA1 and BRCA2 mutations to familial ovarian cancer: no evidence for other ovarian cancer-susceptibility genes.

  12474142   Two percent of men with early-onset prostate cancer harbor germline mutations in the BRCA2 gene.

  15026808   BRCA1 and BRCA2 germline mutation spectrum and frequencies in Belgian breast/ovarian cancer families.

  17924331   A systematic genetic assessment of 1,433 sequence variants of unknown clinical significance in the BRCA1 and BRCA2 breast cancer-predisposition genes.

  19043619   Classifying Variants of Undetermined Significance in BRCA2 with protein likelihood ratios.

  20104584   Characterization of BRCA1 and BRCA2 deleterious mutations and variants of unknown clinical significance in unilateral and bilateral breast cancer: the WECARE study.

  21520273   Assessment of rare BRCA1 and BRCA2 variants of unknown significance using hierarchical modeling.

  21702907   A high-throughput protocol for mutation scanning of the BRCA1 and BRCA2 genes.

  21965345   Clinical impact of unclassified variants of the BRCA1 and BRCA2 genes.

  21990134   A review of a multifactorial probability-based model for classification of BRCA1 and BRCA2 variants of uncertain significance (VUS).

  23108138   A classification model for BRCA2 DNA binding domain missense variants based on homology-directed repair activity.

  24033266   A systematic approach to assessing the clinical significance of genetic variants.

  24323938   Functional assays for analysis of variants of uncertain significance in BRCA2.

  24728327   Germline variation in cancer-susceptibility genes in a healthy, ancestrally diverse cohort: implications for individual genome sequencing.

  25741868   Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology.

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Keto genetics

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Low calorie diet genetic

Dieters can determine which diet would result in more weight loss by undergoing a genetic test,...

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