SNP information rs356219

Research and publications:

  15637659   Linkage disequilibrium patterns and tagSNP transferability among European populations.

  17683088   Tau and alpha-synuclein in susceptibility and dementia in Parkinson's disease.

  18162487   Genetic variability in the SNCA gene influences alpha-synuclein levels in the blood and brain.

  18485051   Multiple alpha-synuclein gene polymorphisms are associated with Parkinson's disease in a Norwegian population.

  18606870   Cerebellar alpha-synuclein levels are reduced in Parkinson's disease and do not correlate with disease-associated SNCA polymorphisms in the Swedish material.

  18985386   Genomewide association study for susceptibility genes contributing to familial Parkinson disease.

  19063963   Genetic predisposition to Parkinson's disease.

  19771175   Genetic variants of the alpha-synuclein gene SNCA are associated with multiple system atrophy.

  19834617   Genetic regulation of alpha-synuclein mRNA expression in various human brain tissues.

  21060011   SNCA variant associated with Parkinson disease and plasma alpha-synuclein level.

  21159074   SNCA, MAPT, and GSK3B in Parkinson disease: a gene-gene interaction study.

  21391235   Independent and joint effects of the MAPT and SNCA genes in Parkinson disease.

  21425343   Replication of MAPT and SNCA, but not PARK16-18, as Parkinson's disease susceptibility genes.

  21812969   Genome-wide association study identifies candidate genes for Parkinson's disease in an Ashkenazi Jewish population.

  22086882   No association between Parkinson disease alleles and the risk of melanoma.

  22349157   SNP rs356219 of the α-synuclein gene (SNCA) is associated with Parkinson's disease in the Chinese Han population.

  22425546   SNCA polymorphisms, smoking, and sporadic Parkinson's disease in Japanese people.

  22438815   A comprehensive review of studies and systematic meta-analysis of the genetics of Parkinson's disease: the PDGene database.

  22530163   Postmortem Interval Influences α-Synuclein Expression in Parkinson Disease Brain.

  22669510   Age at onset in LRRK2-associated PD is modified by SNCA variants.

  22839974   The UCHL1 S18Y variant is a risk factor for Parkinson's disease in Japan.

  22911860   Genome-wide assessment of Parkinson's disease in young people from Finland.

  23674386   SNCA: a major genetic modifier of age of onset of Parkinson's disease.

  23737253   SNCA variant rs356219 increases the risk of sporadic Parkinson's disease in ethnic Chinese.

  23962496   The protective effect of LRRK2 p.R1398H on Parkinson's disease risk is independent of MAPT and SNCA variants.

  25111979   α-Synuclein rs356219 polymorphisms in patients with Gaucher disease and Parkinson disease.

  25178429   APOE, MAPT, and SNCA genes and cognitive performance in Parkinson disease.

  25656566   Alpha-synuclein polymorphisms (SNCA) and susceptibility to Parkinson's disease: a meta-analysis.

  26208350   SNCA genetic variants are associated with susceptibility to Parkinson's disease but not to amyotrophic lateral sclerosis or multiple system atrophy in a Chinese population.

  26297298   Differential expression of α-synuclein splice variants in the brain of alcohol misusers: Influence of genotype.

  26942037   Genetic profile, environmental exposures and their interactions in Parkinson's disease.

  27299523   To study the influence of genetic variants on clinical profiles of Parkinson's disease assessed by the Unified Parkinson's Disease Rating Scale and Hoehn-Yahr stage.

  27335051   Total salivary α-synuclein, oligomeric α-synuclein, and SNCA variants in patients with Parkinson's disease.

  27538639   The SNCA rs356182 variant increases the risk of sporadic Parkinson's disease in ethnic Chinese.

  27699750   Frequency of single nucleotide polymorphisms and alpha-synuclein haplotypes associated with sporadic Parkinson's disease in a Mexican population.

  27979356   Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis.

  28399184   Genetic factors influencing frontostriatal dysfunction and the development of dementia in Parkinson's disease.

  28676755   SNCA gene variants are associated with Parkinson's disease risk and cognitive symptoms in a Brazilian sample.

  28927418   A systematic review and integrative approach to decipher the overall molecular link between levodopa response and Parkinson's disease.

  29473656   β-synuclein (SNCA), but not dynamin 3 (DNM3), influences age of onset of Parkinson's disease with leucine-rich repeat kinase 2 (LRRK2) in Spain.

  29505953   Multimodal neuroimaging and behavioral assessment of α-synuclein polymorphism rs356219 in older adults.

  29652634   Emerging applications of genome-editing technology to examine functionality of GWAS-associated variants for complex traits.

  30048891   Deterioration of executive dysfunction in elderly with REM sleep behavior disorder (RBD).

  30120834   Ethanol (EtOH)-Related Behaviors in α-Synuclein Mutant Mice and Association of SNCA SNPs with Anxiety in EtOH-Dependent Patients.

  30316070   SNCA variants and alpha-synuclein levels in CD45 blood cells in Parkinson's disease.

  30410434   Comprehensive analysis of the relationship between SNCA polymorphisms and the risk of Parkinson's disease.

  30927235   Family-based association study on functional α-synuclein polymorphisms in attention-deficit/hyperactivity disorder.

  31041581   SNCA, but not DNM3 and GAK, modifies the age of onset of LRRK2-related Parkinson's disease in a Chinese population.

  31102707   Alpha-synuclein gene polymorphism influences the risk of dementia in Han Chinese with Parkinson's disease.

  31234232   Single nucleotide polymorphisms of the SNCA and mTOR pathways interact to modulate the age of onset of Parkinson's disease.

  31244647   Variants in the SNCA locus are associated with progression of Parkinson's disease.

  31325611   Association of LEPR polymorphisms with predisposition and inflammatory response in anti-tuberculosis drug-induced liver injury: A pilot prospective investigation in Western Chinese Han population.

  31965629   Motor complications in Parkinson's disease: 13-year follow-up of the CamPaIGN cohort.

  32432761   Association study of SNCA gene polymorphisms with schizophrenia in a Chinese North Han population.

  32484913   Interaction of SNCA gene polymorphisms and T2DM with Parkinson's disease.

  33362685   Metal Exposure and SNCA rs356219 Polymorphism Associated With Parkinson Disease and Parkinsonism.

  33643180   Association of Parkinson's disease SNCA risk polymorphisms with disease progression in newly diagnosed patients.

  33865938   β-syn and SNP rs356219 as a potential biomarker in the blood of Parkinson's disease in Mexican mestizos.

  33995045   Analysis of genetic and non-genetic predictors of levodopa-induced dyskinesia in Parkinson's disease.

  34210990   A systematic review of the associations between common SNCA variants and clinical heterogeneity in Parkinson's disease.

  35106798   GBA and APOE influence cognitive decline in Parkinson's disease: a 10-year population-based study.

  35328997   Association of dietary factors and agrochemical exposure with Parkinson's disease in the province of Brescia, Italy.