SNP information rs2981582

Research and publications:

  17529967   Genome-wide association study identifies novel breast cancer susceptibility loci.

  17529973   A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer.

  17997823   Clinical correlates of low-risk variants in FGFR2, TNRC9, MAP3K1, LSP1 and 8q24 in a Dutch cohort of incident breast cancer cases.

  18224312   Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment

  18285324   Common variation in the fibroblast growth factor receptor 2 gene is not associated with endometriosis risk.

  18326623   Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33.

  18355772   Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers.

  18437204   Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics.

  18462018   Allele-specific up-regulation of FGFR2 increases susceptibility to breast cancer.

  18478591   Studies of genes in the FGF signaling pathway and oral clefts with or without dental anomalies.

  18483326   FGFR2 is a breast cancer susceptibility gene in Jewish and Arab Israeli populations.

  18535005   The search for genes contributing to endometriosis risk

  18612136   Discriminatory accuracy from single-nucleotide polymorphisms in models to predict breast cancer risk.

  18681954   Breast cancer susceptibility loci and mammographic density.

  18708391   Breast cancer risk polymorphisms and interaction with ionizing radiation among U.S. radiologic technologists.

  18772892   Can genes for mammographic density inform cancer aetiology?

  18785201   Novel breast cancer risk alleles and endometrial cancer risk.

  18845558   Genetic variants in fibroblast growth factor receptor 2 (FGFR2) contribute to susceptibility of breast cancer in Chinese women.

  18973230   Breast cancer susceptibility alleles and ovarian cancer risk in 2 study populations.

  19005751   Low penetrance breast cancer predisposition SNPs are site specific.

  19028704   Hormone-dependent effects of FGFR2 and MAP3K1 in breast cancer susceptibility in a population-based sample of post-menopausal African-American and European-American women.

  19088016   Genetic susceptibility loci for breast cancer by estrogen receptor status.

  19092773   Breast cancer susceptibility: current knowledge and implications for genetic counselling.

  19094228   The influence of genetic variation in 30 selected genes on the clinical characteristics of early onset breast cancer.

  19119171   AXIS inhibition protein 2, orofacial clefts and a family history of cancer.

  19219042   Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1.

  19223389   FGFR2 variants and breast cancer risk: fine-scale mapping using African American studies and analysis of chromatin conformation.

  19232126   Association between breast cancer susceptibility loci and mammographic density: the Multiethnic Cohort.

  19304784   Association between invasive ovarian cancer susceptibility and 11 best candidate SNPs from breast cancer genome-wide association study.

  19454617   Genetic variation in the chromosome 17q23 amplicon and breast cancer risk.

  19497954   Histone-acetylated control of fibroblast growth factor receptor 2 intron 2 polymorphisms and isoform splicing in breast cancer.

  19519208   Polygenic susceptibility to breast cancer: current state-of-the-art.

  19536173   Association of FGFR2 gene polymorphisms with the risk of breast cancer in population of West Siberia.

  19567422   Risk of estrogen receptor-positive and -negative breast cancer and single-nucleotide polymorphism 2q35-rs13387042.

  19607694   Low-risk susceptibility alleles in 40 human breast cancer cell lines.

  19639606   Correcting the “winner's curse” in odds ratios based on genome-wide association results for major complex human diseases.

  19738052   A risk variant in an miR-125b binding site in BMPR1B is associated with breast cancer pathogenesis.

  19789366   Evaluation of 11 breast cancer susceptibility loci in African-American women.

  19861516   Variation in the FGFR2 gene and the effects of postmenopausal hormone therapy on invasive breast cancer.

  19931039   Using lifetime risk estimates in personal genomic profiles: estimation of uncertainty.

  20054709   Birth weight, breast cancer susceptibility loci, and breast cancer risk.

  20056625   Variation in the FGFR2 gene and the effect of a low-fat dietary pattern on invasive breast cancer.

  20056641   Multiple genetic variants in telomere pathway genes and breast cancer risk.

  20085711   Leveraging genetic variability across populations for the identification of causal variants.

  20126254   Rare variants create synthetic genome-wide associations.

  20146796   Familial relative risks for breast cancer by pathological subtype: a population-based cohort study.

  20193855   rs2981582 is associated with FGFR2 expression in normal breast.

  20237344   Performance of common genetic variants in breast-cancer risk models.

  20299982   Evaluating cancer epidemiologic risk factors using multiple primary malignancies.

  20300826   Current evidence on the relationship between three polymorphisms in the FGFR2 gene and breast cancer risk: a meta-analysis.

  20348248   Genetic and epigenetic mechanisms down-regulate FGF receptor 2 to induce melanoma-associated antigen A in breast cancer.

  20364400   Quantitative assessment of the effect of FGFR2 gene polymorphism on the risk of breast cancer.

  20453838   Genome-wide association study identifies five new breast cancer susceptibility loci.

  20484103   Genetic and clinical predictors for breast cancer risk assessment and stratification among Chinese women.

  20505153   A compendium of genome-wide associations for cancer: critical synopsis and reappraisal.

  20530438   Unique SNP in CD44 intron 1 and its role in breast cancer development.

  20554749   FGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger women.

  20585100   Genome-wide association studies of cancer.

  20605201   Gene-environment interactions in 7610 women with breast cancer: prospective evidence from the Million Women Study.

  20664043   Incidence of breast cancer and its subtypes in relation to individual and multiple low-penetrance genetic susceptibility loci.

  20677155   [Association of FGFR2 gene polymorphism with estrogen receptor positive breast cancer detected by fluorescent quantitative PCR].

  20699374   Evaluation of breast cancer susceptibility loci in Chinese women.

  20718042   Pooled versus individual genotyping in a breast cancer genome-wide association study.

  20853316   FGFR2 intronic SNPs and breast cancer risk: associations with tumor characteristics and interactions with exogenous exposures and other known breast cancer risk factors.

  20956782   Assessment of clinical validity of a breast cancer risk model combining genetic and clinical information.

  20957429   Discriminatory accuracy and potential clinical utility of genomic profiling for breast cancer risk in BRCA-negative women.

  20959865   Genome-wide association of breast cancer: composite likelihood with imputed genotypes.

  21037853   Breast cancer in the personal genomics era.

  21049069   Identification of Novel Susceptibility Genes for Breast Cancer - Genome-Wide Association Studies or Evaluation of Candidate Genes?

  21060860   Common genetic variants and modification of penetrance of BRCA2-associated breast cancer.

  21102626   Caution in generalizing known genetic risk markers for breast cancer across all ethnic/racial populations.

  21118973   Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction.

  21132113   Direct-to-Consumer Genetic and Genomic Testing: Preparing Nurse Practitioners for Genomic Healthcare.

  21194473   Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study.

  21203894   Cancer susceptibility variants and the risk of adult glioma in a US case-control study.

  21382839   Relation of FGFR2 genetic polymorphisms to the association between oral contraceptive use and the risk of breast cancer in Chinese women.

  21415360   Common genetic variants associated with breast cancer in Korean women and differential susceptibility according to intrinsic subtype.

  21418638   FGFR2 protein expression in breast cancer: nuclear localisation and correlation with patient genotype.

  21445572   Genetic polymorphisms and breast cancer risk: evidence from meta-analyses, pooled analyses, and genome-wide association studies.

  21468051   Polygenic susceptibility to prostate and breast cancer: implications for personalised screening.

  21475998   Replication of five GWAS-identified loci and breast cancer risk among Hispanic and non-Hispanic white women living in the Southwestern United States.

  21497291   Evaluation of nanofluidics technology for high-throughput SNP genotyping in a clinical setting.

  21514219   Genetic variants associated with breast-cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence

  21596841   Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium.

  21639959   Annual conference on hereditary cancers 2009 szczecin, poland. 10-11 december 2009. Abstracts.

  21655367   In search of breast cancer culprits: suspecting the suspected and the unsuspected.

  21702935   Genetic variants in the MRPS30 region and postmenopausal breast cancer risk.

  21748294   Correlation of breast cancer susceptibility loci with patient characteristics, metastasis-free survival, and mRNA expression of the nearest genes.

  21767389   Allele-specific regulation of FGFR2 expression is cell type-dependent and may increase breast cancer risk through a paracrine stimulus involving FGF10.

  21791674   Interactions between genetic variants and breast cancer risk factors in the breast and prostate cancer cohort consortium.

  21795498   Confirmation of 5p12 as a susceptibility locus for progesterone-receptor-positive, lower grade breast cancer.

  21795501   Replication of GWAS breast cancer susceptibility loci in the Women's Health Initiative African American SHARe Study.

  21822685   Genetic variants of fibroblast growth factor receptor 2 (FGFR2) are associated with breast cancer risk in Chinese women of the Han nationality.

  21844186   Common breast cancer susceptibility loci are associated with triple-negative breast cancer.

  21852243   Fine-mapping of breast cancer susceptibility loci characterizes genetic risk in African Americans.

  21869864   An integrative genomics approach to biomarker discovery in breast cancer.

  21965274   Breast cancer susceptibility polymorphisms and endometrial cancer risk: a Collaborative Endometrial Cancer Study.

  22028405   Estimating causal effects of genetic risk variants for breast cancer using marker data from bilateral and familial cases.

  22045194   Combined effect of low-penetrant SNPs on breast cancer risk.

  22053997   Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2.