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SNP information rs2200733

RS2200733

Normal allele: CC

The rs2200733 variant on chromosome 4q25 is associated with risk of atrial fibrillation and ischaemic stroke.

Polymorphism rs2200733 is related to topics like this:

Stroke genes

Ischemic stroke has a multifactorial etiology, with genetic causes playing a significant role,...


Research and publications:

  18224312   Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment

  18931155   Association of rs2200733 at 4q25 with atrial flutter/fibrillation diseases in an Italian population.

  18991354   Risk variants for atrial fibrillation on chromosome 4q25 associate with ischemic stroke.

  19141561   Large scale replication and meta-analysis of variants on chromosome 4q25 associated with atrial fibrillation.

  19359634   Update on the genetics of stroke and cerebrovascular disease 2008.

  19597492   Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry.

  19707791   Assessment of association of rs2200733 on chromosome 4q25 with atrial fibrillation and ischemic stroke in a Chinese Han population.

  20031626   Variation in the 4q25 chromosomal locus predicts atrial fibrillation after coronary artery bypass graft surgery.

  20170812   Chromosome 4q25 variants and atrial fibrillation recurrence after catheter ablation.

  20173747   Common variants in KCNN3 are associated with lone atrial fibrillation.

  20175863   The genetics of ischaemic stroke.

  20335276   PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations.

  20362271   Robust replication of genotype-phenotype associations across multiple diseases in an electronic medical record.

  20606429   Association of RS2200733 but not RS10033464 on 4q25 with atrial fibrillation based on the recessive model in a Taiwanese population.

  20733104   Independent susceptibility markers for atrial fibrillation on chromosome 4q25.

  20831840   Three periods of one and a half decade of ischemic stroke susceptibility gene research: lessons we have learned.

  20850564   R231C mutation in KCNQ1 causes long QT syndrome type 1 and familial atrial fibrillation.

  21058051   New information on the genetics of stroke.

  21076174   Association between familial atrial fibrillation and risk of new-onset atrial fibrillation.

  21121054   Visual integration of results from a large DNA biobank (BioVU) using synthesis-view.

  21245058   Genome-wide association studies of atrial fibrillation: past, present, and future.

  21270277   The same chromosome 9p21.3 locus is associated with type 2 diabetes and coronary artery disease in a Chinese Han population.

  21414601   Usefulness of single nucleotide polymorphism in chromosome 4q25 to predict in-hospital and long-term development of atrial fibrillation and survival in patients undergoing coronary artery bypass grafting.

  21481830   Uncovering an intermediate phenotype associated with rs2200733 at 4q25 in lone atrial fibrillation.

  21629240   Genetic susceptibility to ischemic stroke.

  21760908   Association between variants on chromosome 4q25, 16q22 and 1q21 and atrial fibrillation in the Polish population.

  21793630   Association of rs2200733 at 4q25 with early onset of lone atrial fibrillation in young patients.

  21846873   Large-Scale Candidate Gene Analysis in Whites and African Americans Reveals IL6R Polymorphisms in Atrial Fibrillation: National Heart, Lung, and Blood Institute Candidate Gene Association Resource (CARe) Project of the National Institute

  22326711   There is power in numbers--even/especially in genomic medicine.

  22336519   Genetic loci on chromosomes 4q25, 7p31, and 12p12 are associated with onset of lone atrial fibrillation before the age of 40 years.

  22384221   Characterization of genome-wide association-identified variants for atrial fibrillation in African Americans.

  22403240   Associations between incident ischemic stroke events and stroke and cardiovascular disease-related genome-wide association studies single nucleotide polymorphisms in the Population Architecture Using Genomics and Epidemiology study.

  22818067   Chromosome 4q25 variants are genetic modifiers of rare ion channel mutations associated with familial atrial fibrillation.

  22844511   Common genetic variants associated with sudden cardiac death: the FinSCDgen study.

  22988944   Network-based SNP meta-analysis identifies joint and disjoint genetic features across common human diseases.

  23130627   Variant rs2200733 on chromosome 4q25 confers increased risk of atrial fibrillation: evidence from a meta-analysis.

  23132824   Genetic polymorphisms confer risk of atrial fibrillation in patients with heart failure: a population-based study.

  23178686   Common atrial fibrillation risk alleles at 4q25 predict recurrence after catheter-based atrial fibrillation ablation.

  23428961   Common genetic polymorphism at 4q25 locus predicts atrial fibrillation recurrence after successful cardioversion.

  24065534   Rs2200733 and rs10033464 on chromosome 4q25 confer risk of cardioembolic stroke: an updated meta-analysis.

  24161141   A common variant on chromosome 4q25 is associated with prolonged PR interval in subjects with and without atrial fibrillation.

  24190014   BRG1 variant rs1122608 on chromosome 19p13.2 confers protection against stroke and regulates expression of pre-mRNA-splicing factor SFRS3.

  24270849   Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data.

  25262128   Association between rs2200733 and rs7193343 genetic variants and atrial fibrillation in a Spanish population, and meta-analysis of previous studies.

  25494715   Incidence of dementia in relation to genetic variants at PITX2, ZFHX3, and ApoE ε4 in atrial fibrillation patients.

  25684755   Common genetic variants and response to atrial fibrillation ablation.

  25711478   Association of GWAS-Supported Variants rs2200733 and rs6843082 on Chromosome 4q25 with Ischemic Stroke in the Southern Chinese Han Population.

  25717410   Creation and Validation of an EMR-based Algorithm for Identifying Major Adverse Cardiac Events while on Statins.

  26112950   Rs7193343 polymorphism in zinc finger homeobox 3 (ZFHX3) gene and atrial fibrillation: an updated meta-analysis of 10 case-control comparisons.

  26162320   Chromosome 4q25 Variants rs2200733, rs10033464, and rs1906591 Contribute to Ischemic Stroke Risk.

  26200358   Atrial fibrillation and NPPA gene p.S64R mutation: are cardiologists helpless spectators of healthy mutation carriers?

  26267381   Molecular Basis of Gene-Gene Interaction: Cyclic Cross-Regulation of Gene Expression and Post-GWAS Gene-Gene Interaction Involved in Atrial Fibrillation.

  26272656   Korean Atrial Fibrillation (AF) Network: Genetic Variants for AF Do Not Predict Ablation Success.

  26660272   Gene-guided therapy for catheter-ablation of atrial fibrillation: are we there yet?

  26925117   The 4q25, 1q21, and 16q22 polymorphisms and recurrence of atrial fibrillation after pulmonary vein isolation.

  26935894   Low-frequency and common genetic variation in ischemic stroke: The METASTROKE collaboration.

  27158361   Polymorphism rs2200733 at chromosome 4q25 is associated with atrial fibrillation recurrence after radiofrequency catheter ablation in the Chinese Han population.

  27346453   Association of Genetic Variants at the 4q25 Locus with Atrial Fibrillation in Indian Population.

  27446775   Association Between a Polymorphism (rs2071214) in Baculoviral IAP Repeat Containing 5 Gene (BIRC5) and Ischemic Stroke in Korean Population.

  27713600   Association of Single Nucleotide Polymorphisms with Atrial Fibrillation and the Outcome after Catheter Ablation.

  27765191   PITX2 Modulates Atrial Membrane Potential and the Antiarrhythmic Effects of Sodium-Channel Blockers.

  27824142   Gene-gene Interaction Analyses for Atrial Fibrillation.

  27843048   Common variants predict recurrence after nonfamilial atrial fibrillation ablation in Chinese Han population.

  28258728   Relation of Obstructive Sleep Apnea and a Common Variant at Chromosome 4q25 to Atrial Fibrillation.

  28281580   Association of SCN10A Polymorphisms with the Recurrence of Atrial Fibrillation after Catheter Ablation in a Chinese Han Population.

  29240960   Variant rs2200733 and rs10033464 on chromosome 4q25 are associated with increased risk of atrial fibrillation after catheter ablation: Evidence from a meta-analysis.

  29624624   Genetic modulation of atrial fibrillation risk in a Hispanic/Latino cohort.

  29800783   Analysis of clinical and candidate genetic risk factors for postoperative atrial tachycardia after congenital heart surgery in infants.

  29988284   A Chromosome 4q25 Variant is Associated with Atrial Fibrillation Recurrence After Catheter Ablation: A Systematic Review and Meta-Analysis.

  30177054   Atrial fibrillation associated genetic variation near PITX2 gene increases the risk of preeclampsia.

  30219899   The 4q25 variant rs13143308T links risk of atrial fibrillation to defective calcium homoeostasis.

  30448967   Genotype-phenotype associations in atrial fibrillation: meta-analysis.

  30808078   A Genetic Risk Score for Atrial Fibrillation Predicts the Response to Catheter Ablation.

  31152482   Genetic variants on chromosomes 7p31 and 12p12 are associated with abnormal atrial electrical activation in patients with early-onset lone atrial fibrillation.

  31169720   Association between gene variants and the recurrence of atrial fibrillation: An updated meta-analysis.

  32330377   Single nucleotide polymorphisms of SCN5A and SCN10A genes increase the risk of ventricular arrhythmias during myocardial infarction.

  33213811   Genetic Susceptibility to Atrial Fibrillation Is Associated With Atrial Electrical Remodeling and Adverse Post-Ablation Outcome.

  33350184   The Effects of Single Nucleotide Polymorphisms in Korean Patients with Early-onset Atrial Fibrillation after Catheter Ablation.

  33720624   [Features of genetic manifestations in patients with abdominal obesity during atrial fibrillation in combination with arterial hypertension].

  34308874   Interrelation between the rs2200733 polymorphism of the ATFB5 gene and atrial fibrillation in Uzbek patients.

  34540114   The association between polymorphisms in PITX2 and congenital esophageal atresia susceptibility.

  34833481   A Higher Polygenic Risk Score Is Associated with a Higher Recurrence Rate of Atrial Fibrillation in Direct Current Cardioversion-Treated Patients.

  34946902   The Genetic Landscape of Patent Foramen Ovale: A Systematic Review.

  36061199   Variants rs2200733 and rs6843082 Show Different Associations in Asian and Non-Asian Populations With Ischemic Stroke.

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