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SNP information rs16754

RS16754

Normal allele: TT

Single nucleotide polymorphism rs16754 of the WT1 gene is associated with acute myeloleukaemia in children.

Polymorphism rs16754 is related to topics like this:

Leukemia is it genetic

Acute myeloid leukemia (AML) is a diverse cancer that primarily impacts individuals aged 60 and...


Research and publications:

  15687485   Wilms tumor gene variants are associated with focal segmental glomerulosclerosis in African Americans.

  17267408   Allelic imbalance in gene expression as a guide to cis-acting regulatory single nucleotide polymorphisms in cancer cells.

  19914700   Single-nucleotide polymorphism in WT1 gene in a hyperplastic intralobar nephrogenic rest with botryoid protrusion.

  20038731   Single nucleotide polymorphism in the mutational hotspot of WT1 predicts a favorable outcome in patients with cytogenetically normal acute myeloid leukemia.

  20368538   Impact of IDH1 R132 mutations and an IDH1 single nucleotide polymorphism in cytogenetically normal acute myeloid leukemia: SNP rs11554137 is an adverse prognostic factor.

  20644087   No prognostic impact of the WT1 gene single nucleotide polymorphism rs16754 in pediatric acute myeloid leukemia.

  21189390   Synonymous single nucleotide polymorphism WT1 rs16754 correlates with higher mRNA expression and predicts significantly improved outcome in favorable risk pediatric acute myeloid leukemia: a report from the pediatric oncology group

  21372155   Integrative prognostic risk score in acute myeloid leukemia with normal karyotype.

  21659357   Clinical outcome and gene- and microRNA-expression profiling according to the Wilms tumor 1 (WT1) single nucleotide polymorphism rs16754 in adult de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study.

  21760594   Wilms tumor 1 rs16754 single nucleotide polymorphism does not predict clinical outcome in adult acute myeloid leukemia.

  21798259   WT1 mutations and polymorphisms in Southeast Asian acute myeloid leukemia.

  22015946   Single nucleotide polymorphism of the Wilms tumor 1 gene rs16754 in Korean patients with cytogenetically normal acute myeloid leukemia.

  22506617   WT1 mutations and single nucleotide polymorphism rs16754 analysis of patients with pediatric acute myeloid leukemia in a Chinese population.

  22568493   ID1 expression associates with other molecular markers and is not an independent prognostic factor in cytogenetically normal acute myeloid leukaemia.

  22895555   Analysis of mutational status, SNP rs16754, and expression levels of Wilms tumor 1 (WT1) gene in acute promyelocytic leukemia.

  23070125   Analysis of SNP rs16754 of WT1 gene in a series of de novo acute myeloid leukemia patients.

  23117548   Analysis of WT1, WTX and CTNNB1 mutations in 43 patients with sporadic Wilms tumor.

  23550990   Analysis of WT1 mutations, expression levels and single nucleotide polymorphism rs16754 in de novo non-M3 acute myeloid leukemia.

  23956224   The prognostic effect of high diagnostic WT1 gene expression in pediatric AML depends on the status of the rs16754 WT1 SNP: a report from the Children's Oncology Group.

  25553291   Alteration of the SETBP1 gene and splicing pathway genes SF3B1, U2AF1, and SRSF2 in childhood acute myeloid leukemia.

  25741868   Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology.

  25841655   Wilms Tumor 1 rs16754 predicts favorable clinical outcomes for acute myeloid leukemia patients in South Chinese population.

  25932444   Risk-Reducing Genetic Variant of Wilms Tumor 1 Gene rs16754 in Korean Patients With BCR-ABL1-Negative Myeloproliferative Neoplasm.

  26224397   Wilms tumor gene single nucleotide polymorphism rs16754 predicts a favorable outcome in children with acute lymphoblastic leukemia.

  26358501   Novel WT1 Missense Mutations in Han Chinese Women with Premature Ovarian Failure.

  26499507   The Wilms Tumor-1 (WT1) rs2234593 variant is a prognostic factor in normal karyotype acute myeloid leukemia.

  26644203   A systematic review and meta-analysis of the impact of WT1 polymorphism rs16754 in the effectiveness of standard chemotherapy in patients with acute myeloid leukemia.

  26725263   Prevalence and prognostic impact of Wilms tumor 1 (WT1) gene, including SNP rs16754, in cytogenetically normal acute myeloid leukemia (CN-AML): Iranian experience.

  26992216   The Wilms Tumor-1 (WT1) rs16754 polymorphism is a prognostic factor in acute myeloid leukemia (AML): a meta-analysis.

  29407184   Prognostic value of Wilms tumor-1 (WT1) rs16754 polymorphism in acute myeloid leukemia.

  29958641   Description of the mutation spectrum and polymorphism of the Wilms tumor 1 (WT1) gene in patients with hypospadias in an Indonesian population.

  30082223   Wilms Tumor 1 Expression at Diagnosis Correlates With Genetic Abnormalities and Polymorphism But Is Not Independently Prognostic in Acute Myelogenous Leukemia: A┬áHokkaido Leukemia Net Study.

  30468432   Wilms Tumor-1 (WT1) rs16754 Polymorphism and Clinical Outcome in Acute Myeloid Leukemia.

  30520285   Wilms Tumor-1 (WT1) rs16754 Polymorphism.

  32629644   Association between the Wilms tumor-1 rs16754 polymorphism and acute myeloid leukemia: A MOOSE-compliant meta-analysis.

  33224562   Hotspots mutational analysis of Wilms tumor 1 gene in acute myeloid leukaemia; prevalence and clinical correlation in North Indian population.

  35407481   WT1 Gene Mutations, rs16754 Variant, and WT1 Overexpression as Prognostic Factors in Acute Myeloid Leukemia Patients.

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