SNP information rs157580

Research and publications:

  17658295   Association of ApoE genetic variants with obstructive sleep apnea in children.

  18439548   Loci associated with metabolic syndrome pathways, including LEPR, HNF1A, IL6R, and GCKR, are associated with plasma C-reactive protein: the Women's Genome Health Study.

  18823527   Genome-wide association study of late-onset Alzheimer's disease using pooled DNA.

  19060910   Genome-wide association analysis of metabolic traits in a birth cohort from a founder population

  19060911   Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.

  19668339   Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel Alzheimer's disease susceptibility genes.

  19734902   Genome-wide association study identifies CLU and PICALM variants associated with Alzheimer's disease.

  19919681   Differential binding and co-binding pattern of FOXA1 and FOXA3 and their relation to H3K4me3 in HepG2 cells revealed by ChIP-seq.

  19951432   Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease

  20061627   Genome-wide scanning of copy number alterations in late-onset Alzheimer's disease.

  20236449   Genetics of Alzheimer disease in the pre- and post-GWAS era.

  20502693   Genetics and beyond--the transcriptome of human monocytes and disease susceptibility.

  20838585   Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa heart study.

  20885792   Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities.

  21390209   Meta-analysis of a genome-wide association study identifies multiple variants at the BIN1 locus associated with late-onset Alzheimer's disease.

  21860704   Implications of discoveries from genome-wide association studies in current cardiovascular practice.

  21867541   Evaluation of the global association between cholesterol-related polymorphisms and Alzheimer's disease suggests a role for rs3846662 splicing and HMGCR in disease risk.

  21931794   Common variants in CRP and LEPR influence high sensitivity C-reactive protein levels in North Indians.

  22073310   Association of genetic loci with blood lipids in the Chinese population.

  22159054   A comprehensive genetic association study of Alzheimer disease in African Americans.

  22430674   A genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease.

  22550605   Promising genetic biomarkers of preclinical Alzheimer's disease: impact of APOE and TOMM40 on brain integrity.

  22911757   Association study of candidate gene polymorphisms with amnestic mild cognitive impairment in a Chinese population.

  23193196   Assessment and separation of polygenic variations captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis.

  23288655   Association of TOMM40 polymorphisms with late-onset Alzheimer's disease in a Northern Han population.

  23546992   TOMM40 polymorphisms in Italian patients with Alzheimer's disease and frontotemporal dementia.

  23573206   Genetic loci associated with Alzheimer's disease and cerebrospinal fluid biomarkers in a Finnish case-control cohort.

  24270849   Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data.

  24755620   Overrepresentation of glutamate signaling in Alzheimer's disease: enrichment of network pathways using meta-analysis of genome-wide association studies.

  26154020   A genome-wide screening and SNPs-to-genes approach to identify novel genetic risk factors associated with frontotemporal dementia.

  26252223   Genetic Variants Associated with Lipid Profiles in Chinese Patients with Type 2 Diabetes.

  26252872   Variations in the FRA10AC1 Fragile Site and 15q21 Are Associated with Cerebrospinal Fluid Aβ1-42 Level.

  26680604   Polygenic analysis of late-onset Alzheimer's disease in mainland China.

  26795201   Associations Between Genetic Variants in 19p13 and 19q13 Regions and Susceptibility to Alzheimer Disease: A Meta-Analysis.

  26849123   An Adaptive Ridge Procedure for L0 Regularization.

  28650998   Functional annotation of Alzheimer's disease-associated loci identified by GWAS.

  29670124   BCL3-PVRL2-TOMM40 SNPs, gene-gene and gene-environment interactions on dyslipidemia.

  30319691   Genome-wide association and mechanistic studies suggest that the immune response contributes to the development of Alzheimer's disease.

  30462377   Independent associations of TOMM40 and APOE variants with body mass index.

  32093702   Discovering weaker genetic associations guided by known associations.

  33815092   Genetic variation in molecular pathways associated with Alzheimer's disease: a comprehensive review.

  35124268   Mendelian Randomization Analysis Reveals No Causal Relationship Between Nonalcoholic Fatty Liver Disease and Severe COVID-19.