Normal allele: AA
The IRF4 rs872071 polymorphism causes susceptibility to chronic lymphocytic leukaemia, Hodgkin's lymphoma, skin cancer and haematological malignancies.
Polymorphism rs872071 is related to topics like this:
Research and publications:
18758461 A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia.
19620980 Genetic variants at 6p21.33 are associated with susceptibility to follicular lymphoma.
19804451 IRF4 polymorphism rs872071 and risk of Hodgkin lymphoma.
20332261 Genetic susceptibility variants for chronic lymphocytic leukemia.
20389242 Familial chronic lymphocytic leukemia.
20585100 Genome-wide association studies of cancer.
20585627 Web-based, participant-driven studies yield novel genetic associations for common traits.
20602913 IRF4 variants have age-specific effects on nevus count and predispose to melanoma.
20639881 Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32.
20731705 Genetic susceptibility for chronic lymphocytic leukemia among Chinese in Hong Kong.
20855867 Inherited genetic susceptibility to monoclonal B-cell lymphocytosis.
21131588 Genome-wide association study identifies a novel susceptibility locus at 6p21.3 among familial CLL.
21307401 What are genome-wide association studies telling us about B-cell tumor development?
22235315 Post-GWAS functional characterization of susceptibility variants for chronic lymphocytic leukemia.
26405224 Familial predisposition and genetic risk factors for lymphoma.
28083618 Cereblon and IRF4 Variants Affect Risk and Response to Treatment in Multiple Myeloma.