Normal allele: AA
FGF21 is a sugar-inducible hormone associated with the consumption and preference for sweets in humans. For carriers of the risk allele A, a diet high in protein and limiting carbohydrates has an effective response.
Polymorphism rs838133 is related to topics like this:
Research and publications:
23372041 Novel locus including FGF21 is associated with dietary macronutrient intake.
28467924 FGF21 Is a Sugar-Induced Hormone Associated with Sweet Intake and Preference in Humans.
33763108 Whole Genome Interpretation for a Family of Five.
34095191 Dietary Patterns and Their Associations With the FTO and FGF21 Gene Variants Among Emirati Adults.
35092912 The influence of host genetics on liver microbiome composition in patients with NAFLD.