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SNP information rs733618

Normal allele: TT

CTLA4 gene polymorphism is associated with an increased risk of developing myasthenia gravis.

Polymorphism rs733618 is related to topics like this:

Myasthenia gravis genetic

Myasthenia gravis is a condition that weakens the skeletal muscles, which are responsible for...


Research and publications:

  15452244   Cytotoxic T-lymphocyte antigen 4 gene and recovery from hepatitis B virus infection.

  18059468   A family study of the association of cytotoxic T-lymphocyte antigen-4 with susceptibility to Graves' disease in a Han Chinese population in Taiwan.

  18528295   Influence of cytotoxic T lymphocyte-associated antigen 4 (CTLA4) common polymorphisms on outcome in treatment of melanoma patients with CTLA-4 blockade.

  19264973   Assessing the reproducibility of asthma candidate gene associations, using genome-wide data.

  19300490   An African ancestry-specific allele of CTLA4 confers protection against rheumatoid arthritis in African Americans.

  19500380   LD2SNPing: linkage disequilibrium plotter and RFLP enzyme mining for tag SNPs.

  19609446   CTLA4 autoimmunity-associated genotype contributes to severe pulmonary tuberculosis in an African population.

  19622768   CTLA4 variants, UV-induced tolerance, and risk of non-melanoma skin cancer.

  19956097   Remapping the type I diabetes association of the CTLA4 locus.

  19956101   Overview of the Rapid Response data

  20018068   A comparison of case-only designs for detecting gene x gene interaction in rheumatoid arthritis using genome-wide case-control data in Genetic Analysis Workshop 16.

  20557968   Association analysis of cytotoxic T-lymphocyte antigen 4 gene polymorphisms with primary biliary cirrhosis in Japanese patients.

  20716621   Genetic polymorphisms in adaptive immunity genes and childhood acute lymphoblastic leukemia.

  21513760   Association of CTLA4 gene polymorphisms with lymphatic filariasis in an East Malaysian population.

  22288822   A pilot study on cytotoxic T lymphocyte-4 gene polymorphisms in urinary schistosomiasis.

  22418270   Polymorphisms in cytotoxic T lymphocyte associated antigen-4 influence the rate of acute rejection after renal transplantation in 167 Chinese recipients.

  23261408   -1722T/C polymorphism (rs733618) of CTLA-4 significantly associated with systemic lupus erythematosus (SLE): a comprehensive meta-analysis.

  23300559   Polymorphisms in CTLA4 influence incidence of drug-induced liver injury after renal transplantation in Chinese recipients.

  23628397   Lack of association between CTLA-4 and PDCD1 polymorphisms and acute rejection in German liver transplant recipients.

  23663310   Investigating highly replicated asthma genes as candidate genes for allergic rhinitis.

  24710335   Lack of association between cytotoxic T-lymphocyte antigen 4 (CTLA-4) -1722T/C (rs733618) polymorphism and cancer risk: from a case-control study to a meta-analysis.

  25003519   CTLA4 variants and haplotype contribute genetic susceptibility to myasthenia gravis in northern Chinese population.

  25900029   SNP-SNP interactions of immunity related genes involved in the CD28/B7 pathway with susceptibility to invasive ductal carcinoma of the breast.

  26373706   Study of association of CTLA4 gene variants to non-anterior uveitis.

  26709093   Investigation of Cytotoxic T-lymphocyte antigen 4 Polymorphisms in Gastric Cardia Adenocarcinoma.

  27081086   Effect of CTLA-4 gene polymorphisms on long-term kidney allograft function in Han Chinese recipients.

  27181838   PD-L1 polymorphism can predict clinical outcomes of non-small cell lung cancer patients treated with first-line paclitaxel-cisplatin chemotherapy.

  27255376   Immunogenetic markers associated with a naturally acquired humoral immune response against an N-terminal antigen of Plasmodium vivax merozoite surface protein 1 (PvMSP-1).

  27501803   Gene Polymorphisms for Both Auto-antigen and Immune-Modulating Proteins Are Associated with the Susceptibility of Autoimmune Myasthenia Gravis.

  27800130   The Association Between Viral Infections and Co-stimulatory Gene Polymorphisms in Kidney Transplant Outcomes.

  28097051   CTLA-4 polymorphisms associate with breast cancer susceptibility in Asians: a meta-analysis.

  28274366   Pemphigus vulgaris and pemphigus foliaceus determined by CD86 and CTLA4 polymorphisms.

  29100337   Investigation of Cytotoxic T-lymphocyte antigen-4 polymorphisms in non-small cell lung cancer: a case-control study.

  29264740   CTLA-4 polymorphisms are associated with treatment outcomes of patients with multiple myeloma receiving bortezomib-based regimens.

  29794444   Association of Five Snps in Cytotoxic T-Lymphocyte Antigen 4 and Cancer Susceptibility: Evidence from 67 Studies.

  30009380   Association of CTLA-4 polymorphisms with increased risks of myasthenia gravis.

  30024513   Genetic association of CTLA4 gene with polycystic ovary syndrome in the Chinese Han population.

  30634576   CTLA-4 Genetic Variants Predict Survival in Patients with Sepsis.

  30888206   Lack of Association Between CTLA-4 Genetic Polymorphisms and Noncardiac Gastric Cancer in a Chinese Population.

  30921471   Identification of susceptibility SNPs in CTLA-4 and PTPN22 for scleritis in Han Chinese.

  31473094   Association between CTLA-4 gene polymorphism and myasthenia gravis in a Chinese cohort.

  31475028   Host Genetic Determinants of Hepatitis B Virus Infection.

  31620907   PDCD1 and PDCD1LG1 polymorphisms affect the susceptibility to multiple myeloma.

  31684013   Study of the correlation between Graves' ophthalmopathy and CTLA4 gene polymorphism.

  31765828   Genetic variations in the CXCR5 gene decrease the risk of clinical relapse after discontinuation of nucleos(t)ide analogue therapy in patients with chronic hepatitis B.

  32178688   CTLA-4 polymorphisms and predisposition to digestive system malignancies: a meta-analysis of 31 published studies.

  32545568   CTLA-4 Expression Plays a Role in PSC and PBC Progression.

  33519815   Immune Checkpoint Molecules-Inherited Variations as Markers for Cancer Risk.

  33659002   The Genetics of Human Schistosomiasis Infection Intensity and Liver Disease: A Review.

  33717091   Polymorphisms and Circulating Plasma Protein Levels of Immune Checkpoints (CTLA-4 and PD-1) Are Associated With Posner-Schlossman Syndrome in Southern Chinese.

  33802937   The Role of CTLA4 and Its Polymorphisms in Solid Organ and Haematopoietic Stem Cell Transplantation.

  34008865   Genetic Polymorphisms of Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4) and clinical outcomes post-allogeneic hematopoietic stem cell transplantation: A systematic review and meta-analysis.

  34671352   The Association Between Single-Nucleotide Polymorphisms of Co-Stimulatory Genes Within Non-HLA Region and the Prognosis of Leukemia Patients With Hematopoietic Stem Cell Transplantation.

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