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SNP information rs7202877

RS7202877

Normal allele: TT

Increased risk of islet autoimmunity and type 1 diabetes.

Polymorphism rs7202877 is related to topics like this:

Type 1 diabetes is it genetic

Our latest inclusion in the health report is the Type 1 Diabetes Genetic Risk Score, aimed at...

INSR Gene Insulin Receptor

The gene known as INSR directs the production of insulin receptors - proteins present in various...


Research and publications:

  19430480   Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

  20587799   Genetics of type 1 diabetes: what next?

  20805105   Synthetic associations in the context of genome-wide association scan signals

  20885991   Advances and challenges in biomarker development for type 1 diabetes prediction and prevention using omic technologies.

  21270831   Association between type 1 diabetes and GWAS SNPs in the southeast US Caucasian population.

  21498636   Genome-wide "pleiotropy scan" identifies HNF1A region as a novel pancreatic cancer susceptibility locus.

  21873553   Genetic analysis of adult-onset autoimmune diabetes.

  21980299   A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci.

  22278338   Confirmation of novel type 1 diabetes risk loci in families.

  23457408   Type 2 diabetes risk alleles near BCAR1 and in ANK1 associate with decreased β-cell function whereas risk alleles near ANKRD55 and GRB14 associate with decreased insulin sensitivity in the Danish Inter99 cohort.

  23674605   The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway.

  24749055   Untangling the interplay of genetic and metabolic influences on beta-cell function: Examples of potential therapeutic implications involving TCF7L2 and FFAR1.

  24843659   Insights into the genetic basis of type 2 diabetes.

  24845081   Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study

  24864266   Genetics of type 2 diabetes: insights into the pathogenesis and its clinical application.

  25774817   Genetics of type 2 diabetes-pitfalls and possibilities.

  26904692   Genetic Risk Score Modelling for Disease Progression in New-Onset Type 1 Diabetes Patients: Increased Genetic Load of Islet-Expressed and Cytokine-Regulated Candidate Genes Predicts Poorer Glycemic Control.

  27103840   Pharmacogenetics in type 2 diabetes: influence on response to oral hypoglycemic agents.

  27139004   A Common Susceptibility Gene for Type 2 Diabetes Is Associated with Drug Response to a DPP-4 Inhibitor: Pharmacogenomic Cohort in Okinawa Japan.

  27166975   Pharmacogenetic aspects of the treatment of Type 2 diabetes with the incretin effect enhancers.

  28821857   CDKAL1 rs7756992 is associated with diabetic retinopathy in a Chinese population with type 2 diabetes.

  29070082   Sex influences eQTL effects in SLE and genetic polymorphisms associated with Sjögren's syndrome.

  30188962   Association between RBMS1 gene rs7593730 and BCAR1 gene rs7202877 and Type 2 diabetes mellitus in the Chinese Han population.

  34803393   Pharmacogenomics and Personalized Medicine in Type 2 Diabetes Mellitus: Potential Implications for Clinical Practice.

  35330424   Clinical and Genetic Predictors of Glycemic Control and Weight Loss Response to Liraglutide in Patients with Type 2 Diabetes.

  35456451   Gene-Environment Interaction on Type 2 Diabetes Risk among Chinese Adults Born in Early 1960s.

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Vitamin C DNA

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