SNP information rs662799

Research and publications:

  16670016   Allelic drop-out may occur with a primer binding site polymorphism for the commonly used RFLP assay for the -1131T>C polymorphism of the Apolipoprotein AV gene.

  17357073   Genetic analysis of 103 candidate genes for coronary artery disease and associated phenotypes in a founder population reveals a new association between endothelin-1 and high-density lipoprotein cholesterol

  17903299   A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study

  18078817   Multiple genetic determinants of plasma lipid levels in Caribbean Hispanics.

  18196181   Correction of population stratification in large multi-ethnic association studies

  18441017   An apolipoprotein A-V gene SNP is associated with marked hypertriglyceridemia among Asian-American patients.

  18596051   Polygenic determinants of severe hypertriglyceridemia.

  18789138   The APOA5 Trp19 allele is associated with metabolic syndrome via its association with plasma triglycerides.

  19018513   The association of common genetic variants in the APOA5, LPL and GCK genes with longitudinal changes in metabolic and cardiovascular traits.

  19041386   Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.

  19056598   Association between glucokinase regulatory protein (GCKR) and apolipoprotein A5 (APOA5) gene polymorphisms and triacylglycerol concentrations in fasting, postprandial, and fenofibrate-treated states.

  19057464   Pharmacogenetic association of the APOA1/C3/A4/A5 gene cluster and lipid responses to fenofibrate: the genetics of lipid-lowering drugs and diet network study.

  19148283   Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study.

  19299407   Replication of genetic associations with plasma lipoprotein traits in a multiethnic sample

  19435741   Common lipid-altering gene variants are associated with therapeutic intervention thresholds of lipid levels in older people.

  19656773   A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia.

  19732897   Associations of polymorphisms in the apolipoprotein A1/C3/A4/A5 gene cluster with familial combined hyperlipidaemia in Hong Kong Chinese.

  19787382   Introduction to the DISRUPT postprandial database: subjects, studies and methodologies

  19802338   Genetic loci associated with plasma concentration of low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, apolipoprotein A1, and Apolipoprotein B among 6382 white women in genome-wide analysis with replicatio

  19910639   Genetic association and interaction analysis of USF1 and APOA5 on lipid levels and atherosclerosis.

  20031591   Association of blood lipids with common DNA sequence variants at 19 genetic loci in the multiethnic United States National Health and Nutrition Examination Survey III.

  20054229   Gene-gene interaction between APOA5 and USF1: two candidate genes for the metabolic syndrome.

  20154611   Adaptive genetic variation and heart disease risk.

  20395964   Different effects of apolipoprotein A5 SNPs and haplotypes on triglyceride concentration in three ethnic origins.

  20406163   Fenofibrate and metabolic syndrome.

  20429872   Additive effects of LPL, APOA5 and APOE variant combinations on triglyceride levels and hypertriglyceridemia: results of the ICARIA genetic sub-study

  20452521   Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies.

  20570915   Genetic determinants of major blood lipids in Pakistanis compared with Europeans.

  20571505   A single nucleotide polymorphism in APOA5 determines triglyceride levels in Hong Kong and Guangzhou Chinese.

  20674306   The APOA1/C3/A4/A5 cluster and markers of allostatic load in the Boston Puerto Rican Health Study.

  20831840   Three periods of one and a half decade of ischemic stroke susceptibility gene research: lessons we have learned.

  20832063   Exploring genetic determinants of plasma total cholesterol levels and their predictive value in a longitudinal study

  20876667   Genome-wide significant associations for variants with minor allele frequency of 5% or less--an overview: A HuGE review.

  21054477   Association of a genetic variant in the apolipoprotein A5 gene with the metabolic syndrome in Chinese.

  21130994   Strong association of the APOA5-1131T>C gene variant and early-onset acute myocardial infarction.

  21282362   Mendelian randomization studies do not support a role for raised circulating triglyceride levels influencing type 2 diabetes, glucose levels, or insulin resistance.

  21288825   Association of pharmacogenetic markers with premature discontinuation of first-line anti-HIV therapy: an observational cohort study.

  21324458   Association of gene variants with lipid levels in response to fenofibrate is influenced by metabolic syndrome status.

  21375366   Impact of apolipoprotein A5 (APOA5) polymorphisms on serum triglyceride levels in schizophrenic patients under long-term atypical antipsychotic treatment.

  21423763   Interactions of the apolipoprotein A5 gene polymorphisms and alcohol consumption on serum lipid levels.

  21438666   Association of PON1 and APOA5 gene polymorphisms in a cohort of Indian patients having coronary artery disease with and without type 2 diabetes.

  21463987   Cerebrovascular atherosclerosis in type III hyperlipidemia is modulated by variation in the apolipoprotein A5 gene.

  21467728   Profile of participants and genotype distributions of 108 polymorphisms in a cross-sectional study of associations of genotypes with lifestyle and clinical factors: a project in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study.

  21527746   Triglycerides and heart disease: still a hypothesis?

  21548985   Relationship of APOA5, PPARγ and HL gene variants with serial changes in childhood body mass index and coronary artery disease risk factors in young adulthood.

  21773006   Studies of gene variants related to inflammation, oxidative stress, dyslipidemia, and obesity: implications for a nutrigenetic approach.

  21854571   Apolipoprotein A1/C3/A5 haplotypes and serum lipid levels.

  21860654   Association of the Apolipoprotein A5 Gene -1131T>C Polymorphism with Serum Lipids in Korean Subjects: Impact of Sasang Constitution.

  21860704   Implications of discoveries from genome-wide association studies in current cardiovascular practice.

  22328972   A Database of Gene-Environment Interactions Pertaining to Blood Lipid Traits, Cardiovascular Disease and Type 2 Diabetes.

  22387725   Rapid genotyping of APOA5 -1131T>C polymorphism using high resolution melting analysis with unlabeled probes.

  22425169   Vitamin D dependent effects of APOA5 polymorphisms on HDL cholesterol.

  22517333   Associations of apolipoprotein A5 (APOA5), glucokinase (GCK) and glucokinase regulatory protein (GCKR) polymorphisms and lifestyle factors with the risk of dyslipidemia and dysglycemia in Japanese - a cross-sectional data from the J-MICC Study.

  22553514   Single nucleotide polymorphisms of metabolic syndrome-related genes in primary open angle glaucoma.

  22576629   Synergistic effects of genetic variants of APOA5 and BTN2A1 on dyslipidemia or metabolic syndrome.

  22833659   Gender and single nucleotide polymorphisms in MTHFR, BHMT, SPTLC1, CRBP2, CETP, and SCARB1 are significant predictors of plasma homocysteine normalized by RBC folate in healthy adults.

  22924697   Interactions between the apolipoprotein a1/c3/a5 haplotypes and alcohol consumption on serum lipid levels.

  23050023   Association of genetic variants influencing lipid levels with coronary artery disease in Japanese individuals.

  23065249   Apolipoprotein A5 polymorphisms in Turkish population: association with serum lipid profile and risk of ischemic stroke.

  23150898   Evaluation of seven common lipid associated loci in a large Indian sib pair study.

  23151256   APOA5 Q97X mutation identified through homozygosity mapping causes severe hypertriglyceridemia in a Chilean consanguineous family.

  23236364   Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations.

  23459084   Central obesity in males affected by a dyslipidemia-associated genetic polymorphism on APOA1/C3/A4/A5 gene cluster.

  23497168   Omega-3 fatty acids, polymorphisms and lipid related cardiovascular disease risk factors in the Inuit population.

  23656756   Single nucleotide polymorphisms in CETP, SLC46A1, SLC19A1, CD36, BCMO1, APOA5, and ABCA1 are significant predictors of plasma HDL in healthy adults.

  24178511   Gene-centric association signals for haemostasis and thrombosis traits identified with the HumanCVD BeadChip.

  24402875   Genetic association of lipid metabolism related SNPs with myocardial infarction in the Pakistani population.

  24684850   Association of APOA5 rs662799 and rs3135506 polymorphisms with arterial hypertension in Moroccan patients.

  24709297   Genetic variants of apolipoprotein A5 T-1131C and apolipoprotein E common polymorphisms and their relationship to features of metabolic syndrome in adult dyslipidemic patients.

  24815086   The influence of apolipoprotein A5 T-1131C and apolipoprotein E common genetic variants on the levels of hemostatic markers in dyslipidemic patients.

  24886709   Amerindian-specific regions under positive selection harbour new lipid variants in Latinos.

  24887437   Insulin resistance: regression and clustering.

  24903888   Triglyceride-raising APOA5 genetic variants are associated with obesity and non-HDL-C in Chinese children and adolescents.

  24918908   Genomic and metabolomic profile associated to microalbuminuria.

  24991929   Association of common genetic variants with lipid traits in the Indian population.

  25005712   Genetic loci associated with changes in lipid levels leading to constitution-based discrepancy in Koreans.

  25176936   Common genetic variants contribute to primary hypertriglyceridemia without differences between familial combined hyperlipidemia and isolated hypertriglyceridemia.

  25313938   Influences of APOA5 variants on plasma triglyceride levels in Uyghur population.

  25430627   A genetic risk tool for obesity predisposition assessment and personalized nutrition implementation based on macronutrient intake.

  25500319   Association between polymorphisms in genes involved in lipid metabolism and immunological status in chronically HIV-infected patients.

  25646961   Identification of an interaction between VWF rs7965413 and platelet count as a novel risk marker for metabolic syndrome: an extensive search of candidate polymorphisms in a case-control study.

  25685286   Adiponectin: Probe of the molecular paradigm associating diabetes and obesity.

  25770687   APOA5 variants predispose hyperlipidemic patients to atherogenic dyslipidemia and subclinical atherosclerosis.

  26309253   Positive Association between APOA5 rs662799 Polymorphism and Coronary Heart Disease: A Case-Control Study and Meta-Analysis.

  26365620   Genetic association of APOA5 and APOE with metabolic syndrome and their interaction with health-related behavior in Korean men.

  26365669   Interaction of dietary fat intake with APOA2, APOA5 and LEPR polymorphisms and its relationship with obesity and dyslipidemia in young subjects.

  26446360   Mendelian randomization studies of biomarkers and type 2 diabetes.

  26679785   Apolipoprotein A-V gene therapy for disease prevention / treatment: a critical analysis.

  26690388   Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese.

  26702748   The Relation between Metabolic Syndrome Risk Factors and Genetic Variations of Apolipoprotein V in Relation with Serum Triglyceride and HDL-C Level.

  26824674   Interactions of Environmental Factors and APOA1-APOC3-APOA4-APOA5 Gene Cluster Gene Polymorphisms with Metabolic Syndrome.

  26971241   Influence of Genetic Risk Factors on Coronary Heart Disease Occurrence in Afro-Caribbeans.

  26981194   Complexity of vitamin E metabolism.

  27067897   Association of immune recovery with hyperlipidaemia and apolipoprotein gene polymorphisms following highly active antiretroviral therapy in a cohort of Chinese HIV patients.

  27177774   Interactive effects of C-reactive protein levels on the association between APOE variants and triglyceride levels in a Taiwanese population.

  27222817   Association of G894T eNOS, 4G/5G PAI and T1131C APOA5 polymorphisms with susceptibility to myocardial infarction in Morocco.

  27245511   Effect of dietary energy and polymorphisms in BRAP and GHRL on obesity and metabolic traits.

  27257688   Distinct Patterns of Association of Variants at 11q23.3 Chromosomal Region with Coronary Artery Disease and Dyslipidemia in the Population of Andhra Pradesh, India.

  27342221   Selecting instruments for Mendelian randomization in the wake of genome-wide association studies.