SNP information rs6190

Research and publications:

  10193875   Mutational analysis of the proopiomelanocortin gene in Caucasians with early onset obesity.

  10459864   Natural variants of the beta isoform of the human glucocorticoid receptor do not alter sensitivity to glucocorticoids.

  10914684   Multi-allelic origin of congenital disorder of glycosylation (CDG)-Ic.

  11941477   Mutations in PATCHED-1, the receptor for SONIC HEDGEHOG, are associated with holoprosencephaly.

  20472303   Associations between common arginine vasopressin 1b receptor and glucocorticoid receptor gene variants and HPA axis responses to psychosocial stress in a child psychiatric population.

  20549395   Genetics of post-traumatic stress disorder: review and recommendations for genome-wide association studies

  20680430   No associations between single nucleotide polymorphisms in corticoid receptor genes and heart rate and cortisol responses to a standardized social stress test in adolescents: the TRAILS study.

  20712049   Glucocorticoid receptor gene haplotype structure and steroid therapy outcome in IBD patients.

  21094958   Chronic non-paroxysmal neuropathic pain - Novel phenotype of mutation in the sodium channel SCN9A gene.

  21225419   Gene-environment interactions: early life stress and risk for depressive and anxiety disorders.

  21448414   Molecular mechanism of glucocorticoid resistance in inflammatory bowel disease

  21633323   Variations in the glucocorticoid receptor gene (NR3C1) may be associated with corticosteroid dependence and resistance in children with Crohn's disease.

  21803757   Genetic polymorphisms of the glucocorticoid receptor may affect the phenotype of women with anovulatory polycystic ovary syndrome.

  21967077   A genetic predisposition score for muscular endophenotypes predicts the increase in aerobic power after training: the CAREGENE study.

  22427805   Glucocorticoid receptor 1B and 1C mRNA transcript alterations in schizophrenia and bipolar disorder, and their possible regulation by GR gene variants.

  22445700   The impact of drug metabolizing enzyme polymorphisms on outcomes after antenatal corticosteroid use.

  22781842   Variation in the glucocorticoid receptor gene at rs41423247 moderates the effect of prenatal maternal psychological symptoms on child cortisol reactivity and behavior.

  22812453   Glucocorticoid receptor mRNA and protein isoform alterations in the orbitofrontal cortex in schizophrenia and bipolar disorder.

  23820649   Where genotype is not predictive of phenotype: towards an understanding of the molecular basis of reduced penetrance in human inherited disease

  24497894   A Conceptual Model of Psychoneurological Symptom Cluster Variation in Women with Breast Cancer: Bringing Nursing Research to Personalized Medicine.

  25724472   Polymorphisms in the glucocorticoid receptor gene and in the glucocorticoid-induced transcript 1 gene are associated with disease activity and response to glucocorticoid bridging therapy in rheumatoid arthritis.

  25741362   Use of pharmacogenomics in pediatric renal transplant recipients.

  26260058   Two novel genetic variants in the mineralocorticoid receptor gene associated with spontaneous preterm birth.

  26518448   Case-control study of glucocorticoid receptor and corticotrophin-releasing hormone receptor gene variants and risk of perinatal depression.

  26823689   The cardiovascular and hypothalamus-pituitary-adrenal axis response to stress is controlled by glucocorticoid receptor sequence variants and promoter methylation.

  26873309   Glucocorticoid receptor polymorphisms modulate cardiometabolic risk factors in patients with long-term remission of Cushing's syndrome.

  27081784   A novel approach to understanding the role of polymorphic forms of the NR3C1 and TGF-β1 genes in the modulation of the expression of IL-5 and IL-15 mRNA in asthmatic inflammation.

  27509264   Glucocorticoid Receptor Gene Variants and Neonatal Outcome in Very-Low-Birth-Weight Preterm Infants.

  27528460   HPA axis in major depression: cortisol, clinical symptomatology and genetic variation predict cognition.

  27741480   Glucocorticoid receptor variants in childhood attention-deficit/hyperactivity disorder and comorbid psychiatric disorders.

  28641498   Glucocorticoid Receptor Genetic Variants and Response to Fluoxetine in Major Depressive Disorder.

  28686058   Genetic Associations and Interactions Between the NR3C1 (GR) and NR3C2 (MR) Genes and Aggressive Behavior in a Central South Chinese Han Population.

  29526633   Association between allelic variants of the human glucocorticoid receptor gene and autoimmune diseases: A systematic review and meta-analysis.

  29802709   Association Between NR3C1 Gene Polymorphisms and Toxicity Induced by Glucocorticoids Therapy in Saudi Children with Acute Lymphoblastic Leukemia.

  30210047   Pharmacogenomic markers of glucocorticoid response in the initial phase of remission induction therapy in childhood acute lymphoblastic leukemia.

  30647901   Genetic associations of the response to inhaled corticosteroids in asthma: a systematic review.

  31022961   FKBP5 rs4713916: A Potential Genetic Predictor of Interindividual Different Response to Inhaled Corticosteroids in Patients with Chronic Obstructive Pulmonary Disease in a Real-Life Setting.

  32032633   Dual biomarkers long non-coding RNA GAS5 and its target, NR3C1, contribute to acute myeloid leukemia.

  33019527   The Pathways between Cortisol-Related Regulation Genes and PTSD Psychotherapy.

  33371640   [Influence of CYP3A4, CYP3A5, and NR3C1 genes polymorphism on the effectiveness of glucocorticoid therapy in patients with endocrine ophthalmopathy].

  33562675   The Glucocorticoid Receptor Gene (NR3C1) 9β SNP Is Associated with Posttraumatic Stress Disorder.

  34298075   Glucocorticoid receptor Gene (NR3C1) Polymorphisms and Haplotypes in patients with congenital adrenal hyperplasia.

  34466443   Genetic Variant of Glucocorticoid Receptor Gene at rs41423247 and Its Association with Major Depressive Disorder: A Case-Control Study.

  34721069   The Glucocorticoid Receptor Polymorphism Landscape in Patients With Diamond Blackfan Anemia Reveals an Association Between Two Clinically Relevant Single Nucleotide Polymorphisms and Time to Diagnosis.