Normal allele: GG
The risk allele SNP rs3803662 and mRNA levels of the nearby TOX3 and LOC643714 genes predict unfavourable outcome for breast cancer patients.
Polymorphism rs3803662 is related to topics like this:
Research and publications:
17529967 Genome-wide association study identifies novel breast cancer susceptibility loci.
18326623 Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33.
18681954 Breast cancer susceptibility loci and mammographic density.
18772892 Can genes for mammographic density inform cancer aetiology?
18785201 Novel breast cancer risk alleles and endometrial cancer risk.
18973230 Breast cancer susceptibility alleles and ovarian cancer risk in 2 study populations.
19005751 Low penetrance breast cancer predisposition SNPs are site specific.
19088016 Genetic susceptibility loci for breast cancer by estrogen receptor status.
19092773 Breast cancer susceptibility: current knowledge and implications for genetic counselling.
19219042 Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1.
19454617 Genetic variation in the chromosome 17q23 amplicon and breast cancer risk.
19519208 Polygenic susceptibility to breast cancer: current state-of-the-art.
19607694 Low-risk susceptibility alleles in 40 human breast cancer cell lines.
19789366 Evaluation of 11 breast cancer susceptibility loci in African-American women.
19931039 Using lifetime risk estimates in personal genomic profiles: estimation of uncertainty.
20054709 Birth weight, breast cancer susceptibility loci, and breast cancer risk.
20056641 Multiple genetic variants in telomere pathway genes and breast cancer risk.
20085711 Leveraging genetic variability across populations for the identification of causal variants.
20146796 Familial relative risks for breast cancer by pathological subtype: a population-based cohort study.
20237344 Performance of common genetic variants in breast-cancer risk models.
20332101 Fine scale mapping of the breast cancer 16q12 locus.
20406955 Polymorphisms in the TOX3/LOC643714 locus and risk of breast cancer in African-American women.
20453838 Genome-wide association study identifies five new breast cancer susceptibility loci.
20505153 A compendium of genome-wide associations for cancer: critical synopsis and reappraisal.
20530438 Unique SNP in CD44 intron 1 and its role in breast cancer development.
20585100 Genome-wide association studies of cancer.
20699374 Evaluation of breast cancer susceptibility loci in Chinese women.
20718042 Pooled versus individual genotyping in a breast cancer genome-wide association study.
21037853 Breast cancer in the personal genomics era.
21060860 Common genetic variants and modification of penetrance of BRCA2-associated breast cancer.
21497291 Evaluation of nanofluidics technology for high-throughput SNP genotyping in a clinical setting.
21639959 Annual conference on hereditary cancers 2009 szczecin, poland. 10-11 december 2009. Abstracts.
21655367 In search of breast cancer culprits: suspecting the suspected and the unsuspected.
21844186 Common breast cancer susceptibility loci are associated with triple-negative breast cancer.
21852243 Fine-mapping of breast cancer susceptibility loci characterizes genetic risk in African Americans.
21869864 An integrative genomics approach to biomarker discovery in breast cancer.
22045194 Combined effect of low-penetrant SNPs on breast cancer risk.
22332084 Research advances at the Institute for Nutritional Sciences at Shanghai, China.
22357627 Evaluation of 19 susceptibility loci of breast cancer in women of African ancestry.
22433456 Reproductive aging-associated common genetic variants and the risk of breast cancer.
22532573 The role of genetic breast cancer susceptibility variants as prognostic factors.
22747683 Genetic variants associated with breast size also influence breast cancer risk.
22867275 Genetic predisposition, parity, age at first childbirth and risk for breast cancer.
22972951 Prediction of breast cancer risk by genetic risk factors, overall and by hormone receptor status.
23136140 Genetic susceptibility loci for subtypes of breast cancer in an African American population.
23318652 Hereditary breast cancer in the Han Chinese population.