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SNP information rs3803662

RS3803662

Normal allele: GG

The risk allele SNP rs3803662 and mRNA levels of the nearby TOX3 and LOC643714 genes predict unfavourable outcome for breast cancer patients.

Polymorphism rs3803662 is related to topics like this:

BRCA gene

BRCA stands for "BReast CAncer gene" and refers to two distinct genes, BRCA1 and BRCA2, which have...


Research and publications:

  17529967   Genome-wide association study identifies novel breast cancer susceptibility loci.

  17529974   Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer.

  17997823   Clinical correlates of low-risk variants in FGFR2, TNRC9, MAP3K1, LSP1 and 8q24 in a Dutch cohort of incident breast cancer cases.

  18326623   Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33.

  18355772   Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers.

  18437204   Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics.

  18612136   Discriminatory accuracy from single-nucleotide polymorphisms in models to predict breast cancer risk.

  18681954   Breast cancer susceptibility loci and mammographic density.

  18708391   Breast cancer risk polymorphisms and interaction with ionizing radiation among U.S. radiologic technologists.

  18772892   Can genes for mammographic density inform cancer aetiology?

  18785201   Novel breast cancer risk alleles and endometrial cancer risk.

  18973230   Breast cancer susceptibility alleles and ovarian cancer risk in 2 study populations.

  19005751   Low penetrance breast cancer predisposition SNPs are site specific.

  19088016   Genetic susceptibility loci for breast cancer by estrogen receptor status.

  19092773   Breast cancer susceptibility: current knowledge and implications for genetic counselling.

  19094228   The influence of genetic variation in 30 selected genes on the clinical characteristics of early onset breast cancer.

  19219042   Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1.

  19232126   Association between breast cancer susceptibility loci and mammographic density: the Multiethnic Cohort.

  19304784   Association between invasive ovarian cancer susceptibility and 11 best candidate SNPs from breast cancer genome-wide association study.

  19330030   A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1).

  19454617   Genetic variation in the chromosome 17q23 amplicon and breast cancer risk.

  19519208   Polygenic susceptibility to breast cancer: current state-of-the-art.

  19567422   Risk of estrogen receptor-positive and -negative breast cancer and single-nucleotide polymorphism 2q35-rs13387042.

  19607694   Low-risk susceptibility alleles in 40 human breast cancer cell lines.

  19789366   Evaluation of 11 breast cancer susceptibility loci in African-American women.

  19931039   Using lifetime risk estimates in personal genomic profiles: estimation of uncertainty.

  20054709   Birth weight, breast cancer susceptibility loci, and breast cancer risk.

  20056641   Multiple genetic variants in telomere pathway genes and breast cancer risk.

  20085711   Leveraging genetic variability across populations for the identification of causal variants.

  20146796   Familial relative risks for breast cancer by pathological subtype: a population-based cohort study.

  20213080   Genetic variants in trinucleotide repeat-containing 9 (TNRC9) are associated with risk of estrogen receptor positive breast cancer in a Chinese population.

  20237344   Performance of common genetic variants in breast-cancer risk models.

  20332101   Fine scale mapping of the breast cancer 16q12 locus.

  20406955   Polymorphisms in the TOX3/LOC643714 locus and risk of breast cancer in African-American women.

  20453838   Genome-wide association study identifies five new breast cancer susceptibility loci.

  20484103   Genetic and clinical predictors for breast cancer risk assessment and stratification among Chinese women.

  20505153   A compendium of genome-wide associations for cancer: critical synopsis and reappraisal.

  20530438   Unique SNP in CD44 intron 1 and its role in breast cancer development.

  20554749   FGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger women.

  20585100   Genome-wide association studies of cancer.

  20585626   Identification of a functional genetic variant at 16q12.1 for breast cancer risk: results from the Asia Breast Cancer Consortium.

  20605201   Gene-environment interactions in 7610 women with breast cancer: prospective evidence from the Million Women Study.

  20664043   Incidence of breast cancer and its subtypes in relation to individual and multiple low-penetrance genetic susceptibility loci.

  20699374   Evaluation of breast cancer susceptibility loci in Chinese women.

  20703937   Association between polymorphisms of trinucleotide repeat containing 9 gene and breast cancer risk: evidence from 62,005 subjects.

  20718042   Pooled versus individual genotyping in a breast cancer genome-wide association study.

  20956782   Assessment of clinical validity of a breast cancer risk model combining genetic and clinical information.

  20957429   Discriminatory accuracy and potential clinical utility of genomic profiling for breast cancer risk in BRCA-negative women.

  21037853   Breast cancer in the personal genomics era.

  21049069   Identification of Novel Susceptibility Genes for Breast Cancer - Genome-Wide Association Studies or Evaluation of Candidate Genes?

  21060860   Common genetic variants and modification of penetrance of BRCA2-associated breast cancer.

  21102626   Caution in generalizing known genetic risk markers for breast cancer across all ethnic/racial populations.

  21118973   Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction.

  21132113   Direct-to-Consumer Genetic and Genomic Testing: Preparing Nurse Practitioners for Genomic Healthcare.

  21194473   Assessing interactions between the associations of common genetic susceptibility variants, reproductive history and body mass index with breast cancer risk in the breast cancer association consortium: a combined case-control study.

  21197568   Risk of genome-wide association study newly identified genetic variants for breast cancer in Chinese women of Heilongjiang Province.

  21219822   [Recent progress in genetic variants associated with cancer and their implications in diagnostics development].

  21415360   Common genetic variants associated with breast cancer in Korean women and differential susceptibility according to intrinsic subtype.

  21424380   Potential novel candidate polymorphisms identified in genome-wide association study for breast cancer susceptibility.

  21445572   Genetic polymorphisms and breast cancer risk: evidence from meta-analyses, pooled analyses, and genome-wide association studies.

  21475997   Association between rs3803662 polymorphism of trinucleotide repeat containing 9 gene and breast cancer risk.

  21475998   Replication of five GWAS-identified loci and breast cancer risk among Hispanic and non-Hispanic white women living in the Southwestern United States.

  21497291   Evaluation of nanofluidics technology for high-throughput SNP genotyping in a clinical setting.

  21514219   Genetic variants associated with breast-cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence

  21596841   Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium.

  21639959   Annual conference on hereditary cancers 2009 szczecin, poland. 10-11 december 2009. Abstracts.

  21655367   In search of breast cancer culprits: suspecting the suspected and the unsuspected.

  21748294   Correlation of breast cancer susceptibility loci with patient characteristics, metastasis-free survival, and mRNA expression of the nearest genes.

  21779176   Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1.

  21791674   Interactions between genetic variants and breast cancer risk factors in the breast and prostate cancer cohort consortium.

  21795501   Replication of GWAS breast cancer susceptibility loci in the Women's Health Initiative African American SHARe Study.

  21829388   Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA.

  21844186   Common breast cancer susceptibility loci are associated with triple-negative breast cancer.

  21852243   Fine-mapping of breast cancer susceptibility loci characterizes genetic risk in African Americans.

  21869864   An integrative genomics approach to biomarker discovery in breast cancer.

  21949660   Genetic variants at chromosomes 2q35, 5p12, 6q25.1, 10q26.13, and 16q12.1 influence the risk of breast cancer in men.

  21965274   Breast cancer susceptibility polymorphisms and endometrial cancer risk: a Collaborative Endometrial Cancer Study.

  22028405   Estimating causal effects of genetic risk variants for breast cancer using marker data from bilateral and familial cases.

  22045194   Combined effect of low-penetrant SNPs on breast cancer risk.

  22053997   Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2.

  22087758   Single nucleotide polymorphisms associated with risk of contralateral breast cancer in the Women's Environment, Cancer and Radiation Epidemiology (WECARE) study.

  22160591   A genetic risk predictor for breast cancer using a combination of low-penetrance polymorphisms in a Japanese population.

  22269215   Breast cancer risk assessment with five independent genetic variants and two risk factors in Chinese women.

  22314178   Breast cancer risk prediction and individualised screening based on common genetic variation and breast density measurement.

  22332084   Research advances at the Institute for Nutritional Sciences at Shanghai, China.

  22357627   Evaluation of 19 susceptibility loci of breast cancer in women of African ancestry.

  22433456   Reproductive aging-associated common genetic variants and the risk of breast cancer.

  22452962   A genome-wide association study identifies a breast cancer risk variant in ERBB4 at 2q34: results from the Seoul Breast Cancer Study.

  22454379   Common breast cancer susceptibility variants in LSP1 and RAD51L1 are associated with mammographic density measures that predict breast cancer risk.

  22532573   The role of genetic breast cancer susceptibility variants as prognostic factors.

  22726230   Interactive effect of genetic susceptibility with height, body mass index, and hormone replacement therapy on the risk of breast cancer.

  22747683   Genetic variants associated with breast size also influence breast cancer risk.

  22778704   The association between single-nucleotide polymorphisms of ORAI1 gene and breast cancer in a Taiwanese population.

  22867275   Genetic predisposition, parity, age at first childbirth and risk for breast cancer.

  22910930   Genome-Wide Association Studies (GWAS) breast cancer susceptibility loci in Arabs: susceptibility and prognostic implications in Tunisians.

  22972951   Prediction of breast cancer risk by genetic risk factors, overall and by hormone receptor status.

  23136140   Genetic susceptibility loci for subtypes of breast cancer in an African American population.

  23221726   Gene-environment interactions for breast cancer risk among Chinese women: a report from the Shanghai Breast Cancer Genetics Study.

  23270421   The risk allele of SNP rs3803662 and the mRNA level of its closest genes TOX3 and LOC643714 predict adverse outcome for breast cancer patients.

  23318652   Hereditary breast cancer in the Han Chinese population.

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