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SNP information rs3219090

RS3219090

Normal allele: TT

A common intronic variant of PARP1 increases the risk of melanoma.

Polymorphism rs3219090 is related to topics like this:

Melanoma genes

The incidence of malignant melanoma (MM) is rising sharply, making it one of the most aggressive...

Research and publications:

  19925161   Influence of PARP-1 polymorphisms in patients after traumatic brain injury.

  21976407   Genetic variability in DNA repair and cell cycle control pathway genes and risk of smoking-related lung cancer.

  21983785   Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3.

  23393188   Genome-wide analysis of LXRα activation reveals new transcriptional networks in human atherosclerotic foam cells.

  24906573   Association of interferon regulatory factor 4 gene polymorphisms rs12203592 and rs872071 with skin cancer and haematological malignancies susceptibility: a meta-analysis of 19 case-control studies.

  25077817   Fine mapping of genetic susceptibility loci for melanoma reveals a mixture of single variant and multiple variant regions.

  26998216   Sex-specific genetic effects associated with pigmentation, sensitivity to sunlight, and melanoma in a population of Spanish origin.

  27099827   Polymorphisms in DNA repair and oxidative stress genes associated with pre-treatment cognitive function in breast cancer survivors: an exploratory study.

  27221533   Further evidence for population specific differences in the effect of DNA markers and gender on eye colour prediction in forensics.

  28759004   A common intronic variant of PARP1 confers melanoma risk and mediates melanocyte growth via regulation of MITF.

  29641532   Germline mutations in candidate predisposition genes in individuals with cutaneous melanoma and at least two independent additional primary cancers.

Genetic testing for cancer

Medical tests are employed to detect specific changes or mutations in an individual's genes and...

Colorectal cancer genes

One of the prevalent cancer syndromes that can be inherited is colon cancer. Chromosome 2 contains...

Gastrointestinal tract cancer

The occurrence of gastrointestinal (GI) tract cancers caused by genetic mutations is widespread...

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