SNP information rs2884737

Research and publications:

  16611750   Polymorphisms in the VKORC1 gene are strongly associated with warfarin dosage requirements in patients receiving anticoagulation.

  18030307   Combination of phenotype assessments and CYP2C9-VKORC1 polymorphisms in the determination of warfarin dose requirements in heavily medicated patients.

  18305455   Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin.

  18855533   VKORC1 polymorphisms, haplotypes and haplotype groups on warfarin dose among African-Americans and European-Americans.

  19074728   Relative contribution of CYP2C9 and VKORC1 genotypes and early INR response to the prediction of warfarin sensitivity during initiation of therapy.

  19228618   Estimation of the warfarin dose with clinical and pharmacogenetic data.

  19436136   Association of sequence variations in vitamin K epoxide reductase and gamma-glutamyl carboxylase genes with biochemical measures of vitamin K status.

  20072124   Genetic and clinical predictors of warfarin dose requirements in African Americans.

  20203262   Warfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across 3 racial groups.

  20585445   A novel, single algorithm approach to predict acenocoumarol dose based on CYP2C9 and VKORC1 allele variants.

  20716240   New genetic variant that might improve warfarin dose prediction in African Americans.

  21179214   VKORC1 pharmacogenetics and pharmacoproteomics in patients on warfarin anticoagulant therapy: transthyretin precursor as a potential biomarker.

  21179439   VKORC1 common variation and bone mineral density in the Third National Health and Nutrition Examination Survey.

  21359226   The genomic ancestry of individuals from different geographical regions of Brazil is more uniform than expected.

  21628633   Circulating uncarboxylated matrix gla protein is associated with vitamin K nutritional status, but not coronary artery calcium, in older adults.

  22676711   Pharmacogenomics of warfarin in populations of African descent.

  22952875   Influence of CYP2C9 and VKORC1 on patient response to warfarin: a systematic review and meta-analysis.

  22992668   Pharmacogenomics knowledge for personalized medicine.

  23133420   Pharmacogenomic Diversity among Brazilians: Influence of Ancestry, Self-Reported Color, and Geographical Origin.

  24019055   Effect of CYP2C9, VKORC1, CYP4F2 and GGCX genetic variants on warfarin maintenance dose and explicating a new pharmacogenetic algorithm in South Indian population.

  26444257   Genetic diversity of variants involved in drug response and metabolism in Sri Lankan populations: implications for clinical implementation of pharmacogenomics.

  26940072   Association of Genetic Polymorphisms in the VKORC1 and CYP2C9 Genes with Warfarin Dosage in a Group of Kuwaiti Individuals.

  28079798   Clinical and genetic factors associated with warfarin maintenance dose in northern Chinese patients with mechanical heart valve replacement.

  28592190   Genetic variants associated with warfarin dosage in Kuwaiti population.

  30817750   Reproducibility of pharmacogenetics findings for paclitaxel in a heterogeneous population of patients with lung cancer.

  31869433   Genetic Factors Influencing Warfarin Dose in Black-African Patients: A Systematic Review and Meta-Analysis.

  32326111   Role of Genetic Variations in the Hepatic Handling of Drugs.

  33050895   Population structure and pharmacogenomic risk stratification in the United States.

  34621706   Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform.

  35337356   Cross-ethnic analysis of common gene variants in hemostasis show lopsided representation of global populations in genetic databases.