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SNP information rs2234916

RS2234916

Normal allele: AA

Potassium channel gene polymorphisms and increased risk of heart disease.

Polymorphism rs2234916 is related to topics like this:

KCNT1 potassium sodium-activated channel

A vast group of genes responsible for the production of potassium channels includes the KCNT1 gene....


Research and publications:

  15599   Pyrrolo(1,4)benzodiazepine antitumor antibiotics. In vitro interaction of anthramycin, sibiromycin and tomaymycin with DNA using specifically radiolabelled molecules.

  10984545   A common polymorphism associated with antibiotic-induced cardiac arrhythmia.

  11468227   Screening for mutations and polymorphisms in the genes KCNH2 and KCNE2 encoding the cardiac HERG/MiRP1 ion channel: implications for acquired and congenital long Q-T syndrome.

  12402336   DHPLC analysis of potassium ion channel genes in congenital long QT syndrome.

  14661677   Ethnic differences in cardiac potassium channel variants: implications for genetic susceptibility to sudden cardiac death and genetic testing for congenital long QT syndrome.

  14760488   Genetic variations of KCNQ1, KCNH2, SCN5A, KCNE1, and KCNE2 in drug-induced long QT syndrome patients.

  15599693   Single nucleotide polymorphism map of five long-QT genes.

  17161064   Association of torsades de pointes with novel and known single nucleotide polymorphisms in long QT syndrome genes.

  17210839   Prevalence of long-QT syndrome gene variants in sudden infant death syndrome.

  17534376   Confirmation of associations between ion channel gene SNPs and QTc interval duration in healthy subjects.

  19019189   Common candidate gene variants are associated with QT interval duration in the general population.

  19214780   In silico investigations on functional and haplotype tag SNPs associated with congenital long QT syndromes (LQTSs).

  20400777   Common variants in cardiac ion channel genes are associated with sudden cardiac death.

  21967835   The KCNE genes in hypertrophic cardiomyopathy: a candidate gene study.

  22581653   Paralogous annotation of disease-causing variants in long QT syndrome genes.

  23272793   KCNE genetics and pharmacogenomics in cardiac arrhythmias: much ado about nothing?

  23861362   Interpreting secondary cardiac disease variants in an exome cohort.

  27930701   Natural and Undetermined Sudden Death: Value of Post-Mortem Genetic Investigation.

  32268277   Reanalysis and reclassification of rare genetic variants associated with inherited arrhythmogenic syndromes.

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Calcium score report

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Empath genetics

According to the researchers, genetics play a role in our ability to comprehend and react...

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