SNP information rs1800469

Research and publications:

  15113403   Current limitations of SNP data from the public domain for studies of complex disorders: a test for ten candidate genes for obesity and osteoporosis

  15157284   Patterns of linkage disequilibrium and haplotype distribution in disease candidate genes

  15175276   The transforming growth factor-beta1 (TGFB1) gene is associated with chronic obstructive pulmonary disease (COPD).

  15726497   Gene-environment interaction effects on the development of immune responses in the 1st year of life

  15994430   Concordance of genotypes in pre- and post-lung transplantation DNA samples.

  16385446   A testing framework for identifying susceptibility genes in the presence of epistasis

  16456143   Genetic association analysis of functional impairment in chronic obstructive pulmonary disease.

  16543493   Association of transforming growth factor-beta1 gene polymorphisms with myocardial infarction in patients with angiographically proven coronary heart disease.

  16704031   Lack of association between COPD and transforming growth factor-beta1 (TGFB1) genetic polymorphisms in Koreans.

  16780585   Decorin and TGF-beta1 polymorphisms and development of COPD in a general population.

  16872485   Three allele combinations associated with multiple sclerosis

  16896927   A molecular mechanism for the differential regulation of TGF-beta1 expression due to the common SNP -509C-T (c. -1347C > T).

  17054776   The genetics of chronic obstructive pulmonary disease

  17059371   Large-scale population-based study shows no association between common polymorphisms of the TGFB1 gene and BMD in women.

  17319955   Resequencing of genes for transforming growth factor beta1 (TGFB1) type 1 and 2 receptors (TGFBR1, TGFBR2), and association analysis of variants with diabetic nephropathy.

  17333284   Genetic polymorphisms in transforming growth factor beta-1 (TGFB1) and childhood asthma and atopy.

  17363767   Genetic determinants of emphysema distribution in the national emphysema treatment trial.

  17673695   Transforming growth factor- 1 C-509T polymorphism, oxidant stress, and early-onset childhood asthma.

  18284942   Large-scale analysis of association between polymorphisms in the transforming growth factor beta 1 gene (TGFB1) and osteoporosis: the GENOMOS study.

  18292811   Complex two-gene modulation of lung disease severity in children with cystic fibrosis.

  18366677   Genes implicated in multiple sclerosis pathogenesis from consilience of genotyping and expression profiles in relapse and remission.

  18424453   Interaction between a novel TGFB1 haplotype and CFTR genotype is associated with improved lung function in cystic fibrosis.

  18551993   SNP combinations in chromosome-wide genes are associated with bone mineral density in Taiwanese women

  18571008   Genetic susceptibility of epidermal growth factor +61A>G and transforming growth factor beta1 -509C>T gene polymorphisms with gallbladder cancer.

  18670143   The association of transforming growth factor beta 1 gene polymorphisms with the emphysema phenotype of COPD in Japanese.

  18676870   Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China

  18685869   TGF-beta1 gene polymorphisms and primary vesicoureteral reflux in childhood.

  18687755   Genetic variants in T helper cell type 1, 2 and 3 pathways and gastric cancer risk in a Polish population

  18805939   Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis

  18936436   Prevalence in the United States of selected candidate gene variants: Third National Health and Nutrition Examination Survey, 1991-1994

  19096005   Variants in TGFB1, dust mite exposure, and disease severity in children with asthma.

  19131662   A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients

  19173720   Low frequency of CD4+CD25+ Treg in SLE patients: a heritable trait associated with CTLA4 and TGFbeta gene variants.

  19258388   Genetic variation in the transforming growth factor-beta1 gene is associated with susceptibility to IgA nephropathy.

  19263529   Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach

  19330901   Association of 77 polymorphisms in 52 candidate genes with blood pressure progression and incident hypertension: the Women's Genome Health Study

  19356949   Cytokine SNPs: Comparison of allele frequencies by race and implications for future studies

  19380441   Single nucleotide polymorphism at rs1982073:T869C of the TGFbeta 1 gene is associated with the risk of radiation pneumonitis in patients with non-small-cell lung cancer treated with definitive radiotherapy.

  19559392   A candidate gene association study of 77 polymorphisms in migraine

  19566948   Polymorphisms of TGFB1 and VEGF genes and survival of patients with gastric cancer.

  19835575   The VEGF -634G>C promoter polymorphism is associated with risk of gastric cancer.

  19910030   Evaluation of candidate genes in a genome-wide association study of childhood asthma in Mexicans.

  19933216   The COPD genetic association compendium: a comprehensive online database of COPD genetic associations

  19951401   Chronic obstructive pulmonary disease: towards pharmacogenetics

  20096948   No association between SNPs regulating TGF-β1 secretion and late radiotherapy toxicity to the breast: results from the RAPPER study.

  20233420   Cluster analysis in severe emphysema subjects using phenotype and genotype data: an exploratory investigation.

  20357209   Molecular genetic studies of gene identification for osteoporosis: the 2009 update

  20360039   Components of the transforming growth factor-beta family and the pathogenesis of human Achilles tendon pathology--a genetic association study.

  20417488   Association of fetal inflammation and coagulation pathway gene polymorphisms with neurodevelopmental delay at age 2 years

  20418110   Polymorphisms in cytokine genes and serum cytokine levels among New Mexican women with and without breast cancer

  20479942   Genetic risk factors in lupus nephritis and IgA nephropathy--no support of an overlap.

  20525719   Association of COPD candidate genes with computed tomography emphysema and airway phenotypes in severe COPD.

  20565774   Population based allele frequencies of disease associated polymorphisms in the Personalized Medicine Research Project

  20617153   Detection of fetomaternal genotype associations in early-onset disorders: evaluation of different methods and their application to childhood leukemia.

  21054877   Inflammation gene variants and susceptibility to albuminuria in the U.S. population: analysis in the Third National Health and Nutrition Examination Survey (NHANES III), 1991-1994

  21068203   Genetic variation in the TGF-β signaling pathway and colon and rectal cancer risk.

  21088106   Associations between genetic variation in RUNX1, RUNX2, RUNX3, MAPK1 and eIF4E and riskof colon and rectal cancer: additional support for a TGF-β-signaling pathway.

  21320324   The role of IREB2 and transforming growth factor beta-1 genetic variants in COPD: a replication case-control study.

  21332318   Identification of SNPs associated with susceptibility for development of adverse reactions to radiotherapy.

  21333900   The role of genetics in IBS

  21365634   Genetic variation in the transforming growth factor-β signaling pathway and survival after diagnosis with colon and rectal cancer.

  21387313   Genetic variation in bone morphogenetic protein and colon and rectal cancer.

  21454829   Evaluation of functional genetic variants for breast cancer risk: results from the Shanghai breast cancer study.

  21514219   Genetic variants associated with breast-cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence

  21556788   Lack of association between the TGF-β(1) gene and development of COPD in Asians: a case-control study and meta-analysis.

  21679448   Association of transforming growth factor-β1 gene C-509T and T869C polymorphisms with atherosclerotic cerebral infarction in the Chinese: a case-control study.

  21708280   Candidate gene studies in gallbladder cancer: a systematic review and meta-analysis

  22024213   A novel gene-environment interaction involved in endometriosis

  22066665   Bone mineral density and genetic markers involved in three connected pathways (focal adhesion, actin cytoskeleton regulation and cell cycle): the CUMAGAS-BMD information system.

  22135187   Variants in ABCB1, TGFB1, and XRCC1 genes and susceptibility to viral hepatitis A infection in Mexican Americans.

  22162633   Activation of type I interferon pathway in systemic lupus erythematosus: association with distinct clinical phenotypes.

  22282866   The effects of functional polymorphisms in the TGFβ1 gene on nasopharyngeal carcinoma susceptibility.

  22385796   TGFβ1 SNPs and radio-induced toxicity in prostate cancer patients.

  22513132   Interaction between smoking and functional polymorphism in the TGFB1 gene is associated with ischaemic heart disease and myocardial infarction in patients with rheumatoid arthritis: a cross-sectional study.

  22537351   Association of single nucleotide polymorphisms in the genes ATM, GSTP1, SOD2, TGFB1, XPD and XRCC1 with risk of severe erythema after breast conserving radiotherapy.

  22539603   Pathway analyses identify TGFBR2 as potential breast cancer susceptibility gene: results from a consortium study among Asians.

  22558067   Genes in the ureteric budding pathway: association study on vesico-ureteral reflux patients.

  22607024   TGFB1 genetic polymorphisms and coronary heart disease risk: a meta-analysis.

  22649676   Family Analysis of Linkage and Association of HLA-DRB1, CTLA4, TGFB1, IL4, CCR5, RANTES, MMP9 and TIMP1 Gene Polymorphisms with Multiple Sclerosis.

  22662243   Meta-analysis of the association between transforming growth factor-beta polymorphisms and complications of coronary heart disease.

  22724518   Transforming growth factor β1-509C/T and +869T/C polymorphisms on the risk of upper digestive tract cancer: a meta-analysis based on 10,917 participants.

  22769019   Association of inflammatory gene polymorphisms with ischemic stroke in a Chinese Han population.

  22911757   Association study of candidate gene polymorphisms with amnestic mild cognitive impairment in a Chinese population.

  22931704   The haplotype of the TGFβ1 gene associated with cerebral infarction in Chinese.

  22956967   Genetic associations in acquired immune-mediated bone marrow failure syndromes: insights in aplastic anemia and chronic idiopathic neutropenia.

  22969921   TNF-α -863 polymorphisms and the risk of hepatocellular carcinoma.

  23059779   A study of ethnic differences in TGFβ1 gene polymorphisms and effects on the risk of radiation pneumonitis in non-small-cell lung cancer.

  23094028   Genetic association analysis of complex diseases incorporating intermediate phenotype information.

  23213275   Association of vascular endothelial growth factor, transforming growth factor beta, and interferon gamma gene polymorphisms with proliferative diabetic retinopathy in patients with type 2 diabetes.

  23267696   Association of genetic polymorphisms with chronic obstructive pulmonary disease in the Chinese Han population: a case-control study.

  23284751   SNPs in the TGF-β signaling pathway are associated with increased risk of brain metastasis in patients with non-small-cell lung cancer.

  23352795   Association of TGF-β1 -509 C/T, 29 C/T and 788 C/T gene polymorphisms with chronic periodontitis: a case-control study.

  23416372   Genetic variation in TGFB1 gene and risk of idiopathic recurrent pregnancy loss.

  23554640   Association of transforming growth factor-β1 gene variants with the risk of pneumoconiosis in coal industry workers.

  23697595   SNPs in genes implicated in radiation response are associated with radiotoxicity and evoke roles as predictive and prognostic biomarkers.

  23719583   Genome-wide association study identifies a region on chromosome 11q14.3 associated with late rectal bleeding following radiation therapy for prostate cancer.

  23820649   Where genotype is not predictive of phenotype: towards an understanding of the molecular basis of reduced penetrance in human inherited disease

  23946168   Translational genomics of acquired laryngotracheal stenosis.

  23946381   Genetic variants associated with colorectal cancer risk: comprehensive research synopsis, meta-analysis, and epidemiological evidence.

  23996684   Cytokine and cytokine receptor genes of the adaptive immune response are differentially associated with breast cancer risk in American women of African and European ancestry.