SNP information rs1387153

Research and publications:

  19060907   Variants in MTNR1B influence fasting glucose levels

  19060909   A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk.

  19324940   G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans

  19592620   Examination of type 2 diabetes loci implicates CDKAL1 as a birth weight gene.

  19651812   Common genetic variation near melatonin receptor MTNR1B contributes to raised plasma glucose and increased risk of type 2 diabetes among Indian Asians and European Caucasians

  19933996   Examination of all type 2 diabetes GWAS loci reveals HHEX-IDE as a locus influencing pediatric BMI.

  19937311   Common variants at the GCK, GCKR, G6PC2-ABCB11 and MTNR1B loci are associated with fasting glucose in two Asian populations

  20581827   Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.

  20628598   Common polymorphisms in MTNR1B, G6PC2 and GCK are associated with increased fasting plasma glucose and impaired beta-cell function in Chinese subjects

  20712903   Obesity and diabetes genes are associated with being born small for gestational age: results from the Auckland Birthweight Collaborative study

  20858683   Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.

  21091714   The genetics of type 2 diabetes: what have we learned from GWAS?

  21103332   Combined effects of 19 common variations on type 2 diabetes in Chinese: results from two community-based studies

  21386085   A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium.

  21445555   Association study of type 2 diabetes genetic susceptibility variants and risk of pancreatic cancer: an analysis of PanScan-I data.

  21558052   A low frequency variant within the GWAS locus of MTNR1B affects fasting glucose concentrations: genetic risk is modulated by obesity

  21975967   Genetic determinants of variability in glycated hemoglobin (HbA(1c)) in humans: review of recent progress and prospects for use in diabetes care

  22046406   Association of new loci identified in European genome-wide association studies with susceptibility to type 2 diabetes in the Japanese

  22113416   Single nucleotide polymorphisms in JAZF1 and BCL11A gene are nominally associated with type 2 diabetes in African-American families from the GENNID study

  22233651   A genome-wide association study of gestational diabetes mellitus in Korean women

  22237986   Genetic susceptibility to type 2 diabetes and breast cancer risk in women of European and African ancestry.

  22245784   Melatonin membrane receptors in peripheral tissues: distribution and functions

  22350825   Genetic predisposition to type 2 diabetes is associated with impaired insulin secretion but does not modify insulin resistance or secretion in response to an intervention to lower dietary saturated fat.

  22540250   Race-ethnic differences in the association of genetic loci with HbA1c levels and mortality in U.S. adults: the third National Health and Nutrition Examination Survey (NHANES III).

  22558147   Lack of association of type 2 diabetes susceptibility genotypes and body weight on the development of islet autoimmunity and type 1 diabetes.

  22768333   Association of genetic variants of melatonin receptor 1B with gestational plasma glucose level and risk of glucose intolerance in pregnant Chinese women

  23185337   Joint effect of genetic and lifestyle risk factors on type 2 diabetes risk among Chinese men and women.

  23339409   Reduced genetic influence on childhood obesity in small for gestational age children.

  23560644   Polymorphisms of genes involved in the free radical process in patients with sudden sensorineural hearing loss and Meniere's disease.

  23690305   Genetic variants and the risk of gestational diabetes mellitus: a systematic review

  23761423   Association of risk variants for type 2 diabetes and hyperglycemia with gestational diabetes

  23971978   Unveiling the role of melatonin MT2 receptors in sleep, anxiety and other neuropsychiatric diseases: a novel target in psychopharmacology

  24274136   Biobanking across the phenome - at the center of chronic disease research.

  24843659   Insights into the genetic basis of type 2 diabetes.

  24864266   Genetics of type 2 diabetes: insights into the pathogenesis and its clinical application.

  24946790   Inhibitory G proteins and their receptors: emerging therapeutic targets for obesity and diabetes.

  24959828   Genetic association study with metabolic syndrome and metabolic-related traits in a cross-sectional sample and a 10-year longitudinal sample of chinese elderly population.

  25146448   Relationship between melatonin receptor 1B and insulin receptor substrate 1 polymorphisms with gestational diabetes mellitus: a systematic review and meta-analysis.

  25516658   Case-control study of diabetes-related genetic variants and pancreatic cancer risk in Japan.

  25587982   Cumulative effect and predictive value of genetic variants associated with type 2 diabetes in Han Chinese: a case-control study.

  25658847   Do variants associated with susceptibility to pancreatic cancer and type 2 diabetes reciprocally affect risk?

  25774817   Genetics of type 2 diabetes-pitfalls and possibilities.

  25922310   MTNR1B gene polymorphisms and susceptibility to Type 2 Diabetes: A pilot study in South Indians.

  26084345   Gene-Environment Interactions of Circadian-Related Genes for Cardiometabolic Traits.

  26290879   Association Analysis of Genetic Variants with Type 2 Diabetes in a Mongolian Population in China.

  26648684   Update on genetics and diabetic retinopathy.

  26927084   Nutrigenetics and Nutrimiromics of the Circadian System: The Time for Human Health.

  26964836   Recent progress in genetic and epigenetic research on type 2 diabetes.

  27895820   Sleep, circadian dysrhythmia, obesity and diabetes.

  28821857   CDKAL1 rs7756992 is associated with diabetic retinopathy in a Chinese population with type 2 diabetes.

  28961261   Associations of melatonin receptor gene polymorphisms with Graves' disease.

  29340108   Effect of gene-lifestyle interaction on gestational diabetes risk.

  29871606   Impact of KCNQ1, CDKN2A/2B, CDKAL1, HHEX, MTNR1B, SLC30A8, TCF7L2, and UBE2E2 on risk of developing type 2 diabetes in Thai population.

  29947923   Genetic variants of gestational diabetes mellitus: a study of 112 SNPs among 8722 women in two independent populations.

  30991439   Effects of MTNR1B Genetic Variants on Individual Susceptibility to Gestational Diabetes Mellitus: A Meta-Analysis.

  31580701   MTNR1B genetic polymorphisms as risk factors for gestational diabetes mellitus: a case-control study in a single tertiary care center.

  31787898   MTNR1B Gene Polymorphisms Are Associated With the Therapeutic Responses to Repaglinide in Chinese Patients With Type 2 Diabetes Mellitus.

  32114639   Genetic determinants of gestational diabetes mellitus: a case-control study in two independent populations.

  32434355   The association between melatonin receptor 1B gene polymorphisms and type 2 diabetes mellitus (T2DM) in Chinese populations: a meta-analysis.

  32656703   MTNR1B gene on susceptibility to gestational diabetes mellitus: a two-stage hospital-based study in Southern China.

  33193614   The Role of Genetically Determined Glycemic Traits in Breast Cancer: A Mendelian Randomization Study.

  34117605   Type 2 diabetes is associated with the MTNR1B gene, a genetic bridge between circadian rhythm and glucose metabolism, in a Turkish population.

  34629798   MTNR1B polymorphisms with CDKN2A and MGMT methylation status are associated with poor prognosis of colorectal cancer in Taiwan.