SNP information rs11747270

Research and publications:

  18587394   Genome-wide association identifies more than 30 different susceptibility loci for Crohn's disease.

  19557189   Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions

  19812545   Origins and functional impact of copy number variation in the human genome.

  20106866   Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease.

  20805105   Synthetic associations in the context of genome-wide association scan signals

  21049557   NKX2-3 and IRGM variants are associated with disease susceptibility to IBD in Eastern European patients.

  21487504   Immunopathogenesis of inflammatory bowel disease.

  21548950   Evaluation of 22 genetic variants with risk for Crohn's disease in an Ashkenazi Jewish population: a case-control study.

  21752155   Genetic susceptibility to inflammation and colonic transit in lower functional gastrointestinal disorders: preliminary analysis.

  21830272   Different and overlapping genetic loci in Crohn's disease and ulcerative colitis: correlation with pathogenesis.

  22065112   JAK2 rs10758669 variant in Crohn's disease: alteration of the intestinal barrier as one of the mechanisms of action.

  22174698   A comprehensive analysis of shared loci between systemic lupus erythematosus (SLE) and sixteen autoimmune diseases reveals limited genetic overlap.

  22275320   Pattern recognition receptor and autophagy gene variants are associated with antimicrobial antibody production in Crohn's disease.

  23365659   IRGM variants and susceptibility to inflammatory bowel disease in the German population.

  23844243   GStream: improving SNP and CNV coverage on genome-wide association studies.

  24956270   Large-scale East-Asian eQTL mapping reveals novel candidate genes for LD mapping and the genomic landscape of transcriptional effects of sequence variants.

  25191865   Association of IRGM gene mutations with inflammatory bowel disease in the Indian population.

  27336838   Blood and gut eQTLs from an anti-TNF-resistant Crohn's disease cohort inform genetic association loci for IBD.

  27417217   Variants in the autophagy-related gene IRGM confer susceptibility to non-alcoholic fatty liver disease by modulating lipophagy.

  28983640   A haplotypic variant at the IRGM locus and rs11747270 are related to the susceptibility for chronic periodontitis.

  31654602   Genetic polymorphisms of the ATG16L1 and IRGM genes in Malaysian patients with Crohn's disease.

  33147747   Pathogenic Single Nucleotide Polymorphisms on Autophagy-Related Genes.

  35699756   Immunity-related GTPase IRGM at the intersection of autophagy, inflammation, and tumorigenesis.