SNP information rs10889677

Research and publications:

  17606463   Functional variants of interleukin-23 receptor gene confer risk for rheumatoid arthritis but not for systemic sclerosis.

  17678723   Investigation of the IL23R gene in a Spanish rheumatoid arthritis cohort.

  17786191   rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: a combined analysis of IL23R, CARD15 and OCTN1/2 variants.

  17901940   Association analysis of IL-12B and IL-23R polymorphisms in myocardial infarction.

  17952073   Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.

  18073300   Interleukin (IL)-23 receptor is a major susceptibility gene for Graves' ophthalmopathy: the IL-23/T-helper 17 axis extends to thyroid autoimmunity.

  18200510   CARD15 and IL23R influence Crohn's disease susceptibility but not disease phenotype in a Brazilian population.

  18521914   Contribution of IBD5, IL23R, ATG16L1 and NOD2 to the risk of Crohn's disease in a population-based case-control study: evidence of gene interactions.

  18715515   Lack of evidence linking primary sclerosing cholangitis and primary biliary cirrhosis with Crohn's disease risk alleles in Polish patients.

  19021011   Association studies of the IL-23R gene in autoimmune thyroid disease in the Japanese population.

  19103559   [Susceptibility genetic variants in Hungarian morbus Crohn and ulcerative colitis patients].

  19122664   Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study.

  19175939   IL23R in the Swedish, Finnish, Hungarian and Italian populations: association with IBD and psoriasis, and linkage to celiac disease.

  19317742   Interleukin-23 receptor gene polymorphisms is associated with dilated cardiomyopathy in Chinese Han population.

  19522770   Variants of the IL23R gene are associated with ankylosing spondylitis but not with Sjögren syndrome in Hungarian population samples.

  19757086   Interleukin-23 receptor gene variants in Hungarian systemic lupus erythematosus patients.

  19895338   The association between interleukin-23 receptor gene polymorphisms and systemic lupus erythematosus.

  19918037   Association of interleukin 23 receptor polymorphisms with anti-topoisomerase-I positivity and pulmonary hypertension in systemic sclerosis.

  20082850   Association of interleukin-23 receptor gene polymorphisms with risk of ovarian cancer.

  20454450   Evidence that STAT4 is a common autoimmune gene: rs7574865 is associated with Crohn's disease of the colon and early onset of the disease.

  20505004   On safari to Random Jungle: a fast implementation of Random Forests for high-dimensional data.

  20863779   IL23R +2199A/C polymorphism is associated with decreased risk of certain subtypes of gastric cancer in Chinese: a case-control study.

  20978829   Polymorphisms of the IL23R gene are associated with psoriasis but not with immunoglobulin A nephropathy in a Hungarian population.

  21121902   Detecting epistatic SNPs associated with complex diseases via a Bayesian classification tree search method.

  21253534   The IL23R and IL12B SNPs and haplotypes are strongly associated with the risk of Crohn's disease in the New Zealand population.

  21253733   Interleukin-23 receptor genetic polymorphisms and ankylosing spondylitis susceptibility: a meta-analysis.

  21427131   Improved Crohn's disease risk prediction using a multilocus approach.

  21559399   CEACAM6 gene variants in inflammatory bowel disease.

  21717520   Interleukin-23 receptor polymorphism as a risk factor for oral cancer susceptibility.

  21830272   Different and overlapping genetic loci in Crohn's disease and ulcerative colitis: correlation with pathogenesis.

  21852963   Pervasive sharing of genetic effects in autoimmune disease.

  22045842   Association of IL-12B genetic polymorphism with the susceptibility and disease severity of ankylosing spondylitis.

  22242114   The role of osteopontin haplotypes (OPN/SPP1) in susceptibility to Crohn's disease.

  22242199   Genetic factors of autoimmune thyroid diseases in Japanese.

  22262659   Cutting edge: a variant of the IL-23R gene associated with inflammatory bowel disease induces loss of microRNA regulation and enhanced protein production.

  22346247   The role of ATG16L, NOD2 and IL23R in the pathogenesis of Crohn's disease.

  22457781   Variants in the PTPN2 gene are associated with susceptibility to both Crohn's disease and ulcerative colitis, supporting a common genetic basis for the disease.

  22479607   Analysis of IL12B gene variants in inflammatory bowel disease.

  22654556   Graves' ophthalmopathy: a review of immunogenetics.

  22984500   Association of single nucleotide polymorphisms of IL23R and IL17 with ulcerative colitis risk in a Chinese Han population.

  23042301   Functional genetic variations in the IL-23 receptor gene are associated with risk of breast, lung and nasopharyngeal cancer in Chinese populations.

  23054009   A diversity of IL23R gene haplotype variants was noted in rheumatoid arthritis compared to Crohn's disease and ankylosing spondylitis.

  23093364   Differences in haplotype variants of the interleukin-23 receptor gene in ulcerative colitis compared with Crohn's disease and psoriasis.

  23112570   Suggestive association between PLA2G12A single nucleotide polymorphism rs2285714 and response to anti-vascular endothelial growth factor therapy in patients with exudative age-related macular degeneration.

  23239971   A single nucleotide polymorphism of the miRNA binding site in the 3'-UTR region of the IL23R gene is associated with breast cancer.

  23300802   Polymorphisms modulating PTGER4 expression in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites.

  23365659   IRGM variants and susceptibility to inflammatory bowel disease in the German population.

  23564312   Polymorphisms of the IL-23R gene are associated with primary immune thrombocytopenia but not with the clinical outcome of pulsed high-dose dexamethasone therapy.

  23579029   Protective effect of interleukin-23A (IL23A) haplotype variants on type 1A diabetes mellitus in a Brazilian population.

  23754344   Lack of association between IL-23R gene polymorphisms and systemic lupus erythematosus in a Chinese population.

  23807368   Correlation between interleukin‑23 receptor gene polymorphisms and risk of hepatitis B virus infection in patients.

  24076440   Interleukin-23 receptor genetic variants contribute to susceptibility of multiple cancers.

  24223725   Intestinal DMBT1 expression is modulated by IL23R variants associated with Crohn's disease and a DMBT1 variant that affects the binding of the transcription factors CREB1 and ATF-2.

  24332578   Marked differences of haplotype tagging SNP distribution, linkage, and haplotype profile of IL23 receptor gene in Roma and Hungarian population samples.

  24465869   Genetic variants in microRNA target sites of 37 selected cancer-related genes and the risk of cervical cancer.

  24547735   Association of IL-23 and its receptor gene single-nucleotide polymorphisms with multiple sclerosis in Chinese southern population.

  24586528   Functional polymorphisms in interleukin-23 receptor and susceptibility to esophageal squamous cell carcinoma in Chinese population.

  24670917   Genetic variants in interleukin genes are associated with breast cancer risk and survival in a genetically admixed population: the Breast Cancer Health Disparities Study.

  24703098   Interleukin-23 receptor polymorphism is associated with Alzheimer's disease in Han Chinese.

  24861772   Association of interleukin-23 receptor gene polymorphisms with risk of bladder cancer in Chinese.

  24918007   Clinical and genetic factors predicting response to therapy in patients with Crohn's disease.

  25114582   MicroRNA binding site polymorphisms as biomarkers in cancer management and research.

  25133031   Genetic update on inflammatory factors in ulcerative colitis: Review of the current literature.

  25680555   Interleukin-17FT7488 allele is associated with a decreased risk of colorectal cancer and tumor progression.

  26000774   Aquaporin-4 gene variant independently associated with oedema after intracerebral haemorrhage.

  26399911   Associations between interleukin and interleukin receptor gene polymorphisms and risk of gout.

  26472011   Investigation of association of the IL-12B and IL-23R genetic variations with psoriatic risk in a South Indian Tamil cohort.

  26626589   The variations of IL-23R are associated with susceptibility and severe clinical forms of pulmonary tuberculosis in Chinese Uygurs.

  26678098   Association of interleukin-23 receptor gene polymorphisms with susceptibility to Crohn's disease: a meta-analysis.

  26861312   Association between Genetic Polymorphisms and Response to Anti-TNFs in Patients with Inflammatory Bowel Disease.

  26943356   Differences in gene interactions in patients with Graves' disease stratified by age of onset.

  27014188   Analysis of genetic susceptibility to Graves' disease in a cohort of patients of Italian origin.

  27054030   Dual roles of cytokines in Alzheimer's disease: update on interleukins, TNF-α, TGF-β, and IFN-β.

  27156530   Genetic variation in IBD: progress, clues to pathogenesis and possible clinical utility.

  27902482   IL-23R mutation is associated with ulcerative colitis: A systemic review and meta-analysis.

  28210080   IL23R single nucleotide polymorphisms could be either beneficial or harmful in ulcerative colitis.

  28220389   Polymorphisms in key bone modulator cytokines genes influence bisphosphonates therapy in postmenopausal women.

  28224332   Association of single nucleotide polymorphisms of IL23R and IL17 with necrotizing enterocolitis in premature infants.

  28341819   Interleukin-23 Receptor Gene Variants in Acute Lymphoblastic Leukemia and Their Relation to Prognostic Factors.

  28524801   Association of UGT2B7, UGT1A9, ABCG2, and IL23R polymorphisms with rejection risk in kidney transplant patients.

  28547498   Interleukin (IL)-23 Receptor, IL-17A and IL-17F Gene Polymorphisms in Brazilian Patients with Rheumatoid Arthritis.

  28603427   Pharmacogenetics in inflammatory bowel disease: understanding treatment response and personalizing therapeutic strategies.

  29050281   IL-23R and IL-17A polymorphisms correlate with susceptibility of ankylosing spondylitis in a Southwest Chinese population.

  29118466   Associations of Functional MicroRNA Binding Site Polymorphisms in IL23/Th17 Inflammatory Pathway Genes with Gastric Cancer Risk.

  29148561   The role of IL-23 receptor signaling in inflammation-mediated erosive autoimmune arthritis and bone remodeling.

  29198991   Interleukin-23 receptor polymorphism (rs10889677 A/C) in ankylosing spondylitis: Meta-analysis in Caucasian and Asian populations.

  29370888   Lack of association between rheumatoid arthritis and genetic variants rs10889677, rs11209026 and rs2201841 of IL-23R gene.

  29691688   Associations between interleukin-23R polymorphisms and ankylosing spondylitis susceptibility: an updated meta-analysis.

  29944013   Complex role of IL-23R polymorphisms on ankylosing spondylitis: a meta-analysis.

  29985710   Association of IL17 and IL23R gene polymorphisms with rheumatic heart disease in South Indian population.

  30123371   Multiple Membrane Transporters and Some Immune Regulatory Genes are Major Genetic Factors to Gout.

  30324113   Lack of Association between Interleukin 23R (IL-23R) rs10889677 Polymorphism and Inflammatory Bowel Disease Susceptibility In an Iranian Population.

  30646942   Association between IL23R and ERAP1 polymorphisms and sacroiliac or spinal MRI inflammation in spondyloarthritis: DESIR cohort data.

  30833806   Lethal-7-related polymorphisms are associated with susceptibility to and prognosis of gastric cancer.

  31052430   Genetic Studies of Inflammatory Bowel Disease-Focusing on Asian Patients.

  31123953   Interleukin-23 receptor (IL-23R) gene polymorphisms and haplotypes associated with the risk of preeclampsia: evidence from cross-sectional and in silico studies.

  31546198   Single nucleotide polymorphism rs10889677 in miRNAs Let-7e and Let-7f binding site of IL23R gene is a strong colorectal cancer determinant: Report and meta-analysis.

  31701644   Association analysis of interleukin-23 receptor SNPs and SAPHO syndrome in Chinese people.

  31728561   Genetic association between IL23R rs11209026 and rs10889677 polymorphisms and the risk of Crohn's disease and ulcerative colitis: evidence from 41 studies.

  32051081   [Association of interleukin-23 receptor and interleukin-17 single nucleotide polymorphisms with necrotizing enterocolitis in Chinese Han preterm infants].