Normal allele: GG
A common variant of the SIAH2 locus is associated with estrogen-positive breast cancer.
Polymorphism rs865686 is related to topics like this:
Research and publications:
21263130 Novel breast cancer susceptibility locus at 9q31.2: results of a genome-wide association study.
21844186 Common breast cancer susceptibility loci are associated with triple-negative breast cancer.
21852243 Fine-mapping of breast cancer susceptibility loci characterizes genetic risk in African Americans.
22972951 Prediction of breast cancer risk by genetic risk factors, overall and by hormone receptor status.
23136140 Genetic susceptibility loci for subtypes of breast cancer in an African American population.
24025454 Hereditary breast cancer: ever more pieces to the polygenic puzzle.
24359602 Common breast cancer risk variants in the post-COGS era: a comprehensive review.
24743323 Genetic predisposition to in situ and invasive lobular carcinoma of the breast.
24771903 Breast Cancer Risk - From Genetics to Molecular Understanding of Pathogenesis.
25027274 Testing calibration of risk models at extremes of disease risk.
25611573 Association of breast cancer risk loci with breast cancer survival.
25652398 Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2.
26070784 Genetic risk variants associated with in situ breast cancer.
26884359 Genetic predisposition to ductal carcinoma in situ of the breast.