SNP information rs8103142

Research and publications:

  19749757   Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C

  20184973   Interleukin-28b: a key piece of the hepatitis C virus recovery puzzle

  20887330   High sensitivity assay using serum sample for IL28B genotyping to predict treatment response in chronic hepatitis C patients.

  20931559   IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in patients with chronic hepatitis C

  20950615   IL28B and the control of hepatitis C virus infection

  21070502   Interleukin-28B polymorphisms are associated with hepatitis C virus clearance and viral load in a HIV-1-infected cohort

  21303914   Interferon lambdas: the next cytokine storm

  21346780   IL28B genetic variations are associated with high sustained virological response (SVR) of interferon-α plus ribavirin therapy in Taiwanese chronic HCV infection

  21360716   Estimating the net contribution of interleukin-28B variation to spontaneous hepatitis C virus clearance

  21389156   The rs8099917 polymorphism, when determined by a suitable genotyping method, is a better predictor for response to pegylated alpha interferon/ribavirin therapy in Japanese patients than other single nucleotide polymorphisms associated with inter

  21479134   IL28B SNP rs12979860 is a critical predictor for on-treatment and sustained virologic response in patients with hepatitis C virus genotype-1 infection

  21694902   New strategies for the treatment of hepatitis C virus infection and implications of resistance to new direct-acting antiviral agents

  21820962   Interferon-lambda and therapy for chronic hepatitis C virus infection

  21884576   Identification of improved IL28B SNPs and haplotypes for prediction of drug response in treatment of hepatitis C using massively parallel sequencing in a cross-sectional European cohort

  22046316   Genetic variation of the IL-28B promoter affecting gene expression

  22162829   Evolutionary genetic dissection of human interferons.

  22214245   Genomics and proteomics in liver fibrosis and cirrhosis

  22234924   Combined effects of different interleukin-28B gene variants on the outcome of dual combination therapy in chronic hepatitis C virus type 1 infection

  22253847   Sequence analysis of the IL28A/IL28B inverted gene duplication that contains polymorphisms associated with treatment response in hepatitis C patients

  22275900   Pharmacogenomics: what is next?

  22295096   Genetic variations in IL28B and allergic disease in children.

  22328925   Deciphering the interleukin 28B variants that better predict response to pegylated interferon-α and ribavirin therapy in HCV/HIV-1 coinfected patients

  22649509   IL28B genetic variation is associated with spontaneous clearance of hepatitis C virus, treatment response, serum IL-28B levels in Chinese population.

  22719902   Analysis of IL28B variants in an Egyptian population defines the 20 kilobases minimal region involved in spontaneous clearance of hepatitis C virus.

  23109451   IL28B polymorphisms predict the response to chronic hepatitis C virus infection treatment in a Mexican population.

  23135762   Hepatitis C virus kinetics by administration of pegylated interferon-α in human and chimeric mice carrying human hepatocytes with variants of the IL28B gene.

  23268841   Pharmacogenomics of hepatitis C infections: personalizing therapy.

  23866096   The predictive value of IL28B rs12979860, rs11881222 and rs8099917 polymorphisms and IP-10 in the therapeutic response of Egyptian genotype 4 patients.

  24039372   Extended therapy duration for therapy-refractory hepatitis C patients with genotype 2.

  24696021   Interleukin-28B polymorphisms and response of chronic hepatitis C patients from Indonesia to pegylated interferon/ribavirin treatment.

  25032184   No association between the IL28B SNP and response to peginterferon plus ribavirin combination treatment in Korean chronic hepatitis C patients.

  25803108   Favourable IFNL3 genotypes are associated with spontaneous clearance and are differentially distributed in Aboriginals in Canadian HIV-hepatitis C co-infected individuals.

  25837166   IL28B is associated with outcomes of chronic HBV infection.

  26403160   Vaniprevir plus peginterferon alfa-2b and ribavirin in treatment-naive Japanese patients with hepatitis C virus genotype 1 infection: a randomized phase III study.

  26546777   IL28B gene polymorphisms and Th1/Th2 cytokine levels might be associated with HTLV-associated arthropathy.

  26984148   Responder Interferon λ Genotypes Are Associated With Higher Risk of Liver Fibrosis in HIV-Hepatitis C Virus Coinfection.

  27047766   Evaluation of Interferon Resistance in Newly Established Genotype 1b Hepatitis C Virus Cell Culture System.

  27733412   Hepatitis B virus infection in Chinese patients with hepatitis C virus infection: prevalence, clinical characteristics, viral interactions and host genotypes: a nationwide cross-sectional study.

  30402710   Interleukin 28A.rs12980602 and interleukin 28B.rs8103142 genotypes could be protective against HCV infection among Egyptians.

  34452889   Association of IL28 B and IL10 Polymorphism with HCV Infection and Direct Antiviral Treatment.