SNP information rs8042374

Research and publications:

  18414406   Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence

  18519524   Variants in nicotinic receptors and risk for nicotine dependence

  18978787   Common 5p15.33 and 6p21.33 variants influence lung cancer risk.

  19628476   Association of serum cotinine level with a cluster of three nicotinic acetylcholine receptor genes (CHRNA3/CHRNA5/CHRNB4) on chromosome 15

  19654303   Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study.

  19706762   The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans

  19955392   Role of 5p15.33 (TERT-CLPTM1L), 6p21.33 and 15q25.1 (CHRNA5-CHRNA3) variation and lung cancer risk in never-smokers.

  20585100   Genome-wide association studies of cancer.

  21559498   Chromosome 15q25 (CHRNA3-CHRNA5) variation impacts indirectly on lung cancer risk

  21949713   Genetics of sputum gene expression in chronic obstructive pulmonary disease.

  23056235   Functional polymorphisms of CHRNA3 predict risks of chronic obstructive pulmonary disease and lung cancer in Chinese.

  23689675   Genetic risk for nicotine dependence in the cholinergic system and activation of the brain reward system in healthy adolescents.

  23870182   Bridging the clinical gaps: genetic, epigenetic and transcriptomic biomarkers for the early detection of lung cancer in the post-National Lung Screening Trial era.

  24686516   CHRNA3 polymorphism modifies lung adenocarcinoma risk in the Chinese Han population.

  25233467   Role of nicotine dependence on the relationship between variants in the nicotinic receptor genes and risk of lung adenocarcinoma.

  25302169   Acetylcholine receptor pathway in lung cancer: New twists to an old story.

  25415319   Association of GWAS-identified lung cancer susceptibility loci with survival length in patients with small-cell lung cancer treated with platinum-based chemotherapy.

  26831765   Association between two CHRNA3 variants and susceptibility of lung cancer: a meta-analysis.

  26942719   Chromosome 15q25 (CHRNA3-CHRNB4) Variation Indirectly Impacts Lung Cancer Risk in Chinese Males.

  27028512   Genetic Evaluation of Schizophrenia Using the Illumina HumanExome Chip.

  27230571   Different dietary patterns and reduction of lung cancer risk: A large case-control study in the U.S.

  28827732   Genetic predisposition to lung cancer: comprehensive literature integration, meta-analysis, and multiple evidence assessment of candidate-gene association studies.

  29942042   A decade in psychiatric GWAS research.