SNP information rs7961581

Research and publications:

  18372903   Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

  18567820   Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-a

  18591388   Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk

  18694974   Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study

  18714373   Novel meta-analysis-derived type 2 diabetes risk loci do not determine prediabetic phenotypes.

  18782870   Clinical review: the genetics of type 2 diabetes: a realistic appraisal in 2008

  18852197   Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants

  19020323   Genotype score in addition to common risk factors for prediction of type 2 diabetes

  19056611   Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data

  19096518   A novel association of HK1 with glycated hemoglobin in a nondiabetic population: a genome-wide assessment of 14,618 Women's Genome Health Study participants.

  19207020   Meta-analysis in genome-wide association studies

  19323962   Genome-wide association studies in type 2 diabetes

  19324937   Previously associated type 2 diabetes variants may interact with physical activity to modify the risk of impaired glucose regulation and type 2 diabetes: a study of 16,003 Swedish adults

  19341491   Genome-based prediction of common diseases: methodological considerations for future research

  19401414   Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population

  19455301   Replication study for the association of new meta-analysis-derived risk loci with susceptibility to type 2 diabetes in 6,244 Japanese individuals.

  19460916   Genetic architecture of type 2 diabetes: recent progress and clinical implications

  19502414   Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5,327 nondiabetic Finnish men

  19526209   Is the thrifty genotype hypothesis supported by evidence based on confirmed type 2 diabetes- and obesity-susceptibility variants?

  19602701   Underlying genetic models of inheritance in established type 2 diabetes associations

  19639606   Correcting the “winner's curse” in odds ratios based on genome-wide association results for major complex human diseases.

  19734549   Ranking of genome-wide association scan signals by different measures

  19741467   Association of common type 2 diabetes risk gene variants and posttransplantation diabetes mellitus in renal allograft recipients in Korea.

  19789630   Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients--EUGENE2 study.

  19794065   Polygenic risk variants for type 2 diabetes susceptibility modify age at diagnosis in monogenic HNF1A diabetes

  19833888   Gene variants in the novel type 2 diabetes loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B affect different aspects of pancreatic beta-cell function

  19833889   Genetic heterogeneity in latent autoimmune diabetes is linked to various degrees of autoimmune activity: results from the Nord-Trøndelag Health Study

  19862325   PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 and SLC30A8 are associated with type 2 diabetes in a Chinese population

  19902174   Diet-induced gene expression of isolated pancreatic islets from a polygenic mouse model of the metabolic syndrome.

  19956539   How many genetic variants remain to be discovered?

  20017978   Influence of control selection in genome-wide association studies: the example of diabetes in the Framingham Heart Study

  20018066   Epistatic interactions of CDKN2B-TCF7L2 for risk of type 2 diabetes and of CDKN2B-JAZF1 for triglyceride/high-density lipoprotein ratio longitudinal change: evidence from the Framingham Heart Study

  20043853   Prioritizing genes for follow-up from genome wide association studies using information on gene expression in tissues relevant for type 2 diabetes mellitus

  20075150   Utility of genetic and non-genetic risk factors in prediction of type 2 diabetes: Whitehall II prospective cohort study

  20144327   A genomics study of type 2 diabetes mellitus in U.S. Air Force personnel

  20161779   Investigation of type 2 diabetes risk alleles support CDKN2A/B, CDKAL1, and TCF7L2 as susceptibility genes in a Han Chinese cohort

  20712903   Obesity and diabetes genes are associated with being born small for gestational age: results from the Auckland Birthweight Collaborative study

  20805105   Synthetic associations in the context of genome-wide association scan signals

  20816152   Obesity and diabetes genetic variants associated with gestational weight gain.

  20862305   Identification of new genetic risk variants for type 2 diabetes.

  20865176   Consistent association of type 2 diabetes risk variants found in europeans in diverse racial and ethnic groups.

  20870969   Genetic predisposition to long-term nondiabetic deteriorations in glucose homeostasis: Ten-year follow-up of the GLACIER study

  20886378   Physiologic characterization of type 2 diabetes-related loci

  20980412   Impact of positive family history and genetic risk variants on the incidence of diabetes: the Finnish Diabetes Prevention Study

  21036813   A variable selection method for genome-wide association studies.

  21084393   Type 2 diabetes (T2D) associated polymorphisms regulate expression of adjacent transcripts in transformed lymphocytes, adipose, and muscle from Caucasian and African-American subjects.

  21091714   The genetics of type 2 diabetes: what have we learned from GWAS?

  21124985   Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locus.

  21217814   Presymptomatic risk assessment for chronic non-communicable diseases.

  21278902   Genetic risk profiling for prediction of type 2 diabetes

  21357383   No association of risk variants for diabetes and obesity with breast cancer: the Multiethnic Cohort and PAGE studies.

  21378175   Updated genetic score based on 34 confirmed type 2 diabetes Loci is associated with diabetes incidence and regression to normoglycemia in the diabetes prevention program

  21407270   Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration.

  21421807   Effects of 34 risk loci for type 2 diabetes or hyperglycemia on lipoprotein subclasses and their composition in 6,580 nondiabetic Finnish men

  21424820   Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration.

  21602532   Type 2 diabetes risk variants and colorectal cancer risk: the Multiethnic Cohort and PAGE studies.

  21750171   No association of type 2 diabetes risk variants and prostate cancer risk: the multiethnic cohort and PAGE.

  22052079   Association analysis of 31 common polymorphisms with type 2 diabetes and its related traits in Indian sib pairs.

  22113416   Single nucleotide polymorphisms in JAZF1 and BCL11A gene are nominally associated with type 2 diabetes in African-American families from the GENNID study

  22125221   Transethnic meta-analysis of genomewide association studies.

  22350825   Genetic predisposition to type 2 diabetes is associated with impaired insulin secretion but does not modify insulin resistance or secretion in response to an intervention to lower dietary saturated fat.

  22364391   The combined effect of the T2DM susceptibility genes is an important risk factor for T2DM in non-obese Japanese: a population based case-control study.

  22377712   Association between type 2 diabetes genetic susceptibility loci and visceral and subcutaneous fat area as determined by computed tomography

  22923468   Contribution of common genetic variation to the risk of type 2 diabetes in the Mexican Mestizo population.

  22937206   Single nucleotide polymorphisms of the adult intestinal stem cell marker Lgr5 in primary and metastatic colorectal cancer.

  22971100   Quick, "imputation-free" meta-analysis with proxy-SNPs.

  23013243   Maternal and offspring fasting glucose and type 2 diabetes-associated genetic variants and cognitive function at age 8: a Mendelian randomization study in the Avon Longitudinal Study of Parents and Children

  23073174   From genotype to human β cell phenotype and beyond

  23185337   Joint effect of genetic and lifestyle risk factors on type 2 diabetes risk among Chinese men and women.

  23185617   Genetic variant SLC2A2 [corrected] Is associated with risk of cardiovascular disease – assessing the individual and cumulative effect of 46 type 2 diabetes related genetic variants

  23193118   Association of type 2 diabetes susceptibility variants with advanced prostate cancer risk in the Breast and Prostate Cancer Cohort Consortium

  23349771   Association study of 25 type 2 diabetes related Loci with measures of obesity in Indian sib pairs.

  23456907   Maternal genotype and gestational diabetes

  23462794   Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets

  24719615   Genetic susceptibility to type 2 diabetes and obesity: follow-up of findings from genome-wide association studies.

  24736664   Validation of type 2 diabetes risk variants identified by genome-wide association studies in Han Chinese population: a replication study and meta-analysis.

  24843659   Insights into the genetic basis of type 2 diabetes.

  24864266   Genetics of type 2 diabetes: insights into the pathogenesis and its clinical application.

  24926958   Evaluation of common type 2 diabetes risk variants in a South Asian population of Sri Lankan descent.

  24929251   Gene-carbohydrate and gene-fiber interactions and type 2 diabetes in diverse populations from the National Health and Nutrition Examination Surveys (NHANES) as part of the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) study.

  24982668   Estimating the predictive ability of genetic risk models in simulated data based on published results from genome-wide association studies.

  25145545   Does genetic heterogeneity account for the divergent risk of type 2 diabetes in South Asian and white European populations?

  25587982   Cumulative effect and predictive value of genetic variants associated with type 2 diabetes in Han Chinese: a case-control study.

  25774817   Genetics of type 2 diabetes-pitfalls and possibilities.

  26240488   Utilizing Genetic Predisposition Score in Predicting Risk of Type 2 Diabetes Mellitus Incidence: A Community-based Cohort Study on Middle-aged Koreans.

  26500707   Association of JAZF1 and TSPAN8/LGR5 variants in relation to type 2 diabetes mellitus in a Saudi population.

  26930408   Association between Maternal Fish Consumption and Gestational Weight Gain: Influence of Molecular Genetic Predisposition to Obesity.

  26964836   Recent progress in genetic and epigenetic research on type 2 diabetes.

  26983698   Joint effects of diabetic-related genomic loci on the therapeutic efficacy of oral anti-diabetic drugs in Chinese type 2 diabetes patients.

  27053236   Evaluation of type 2 diabetes genetic risk variants in Chinese adults: findings from 93,000 individuals from the China Kadoorie Biobank.

  27383215   Type 2 Diabetes Risk Allele Loci in the Qatari Population.

  28274157   HNF1B, TSPAN8 and NOTCH2 gene polymorphisms in women with gestational diabetes.

  28738793   Association between 28 single nucleotide polymorphisms and type 2 diabetes mellitus in the Kazakh population: a case-control study.

  28821857   CDKAL1 rs7756992 is associated with diabetic retinopathy in a Chinese population with type 2 diabetes.

  32260174   A Replication Study Identified Seven SNPs Associated with Quantitative Traits of Type 2 Diabetes among Chinese Population in A Cross-Sectional Study.