SNP information rs6675281

Research and publications:

  15386212   Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder.

  19255581   Association of DISC1 and TSNAX genes and affective disorders in the depression case-control (DeCC) and bipolar affective case-control (BACCS) studies.

  19300510   The DISC1 pathway modulates expression of neurodevelopmental, synaptogenic and sensory perception genes.

  19414483   The DISC locus and schizophrenia: evidence from an association study in a central European sample and from a meta-analysis across different European populations.

  19805229   DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms.

  20360304   The DISC1 Ser704Cys substitution affects centrosomal localization of its binding partner PCM1 in glia in human brain.

  20505556   Association of DISC1 gene with schizophrenia in families from two distinct French and Algerian populations.

  20531374   Association of Disrupted in Schizophrenia 1 (DISC1) missense variants with ultra-resistant schizophrenia.

  20951727   Neuroplasticity signaling pathways linked to the pathophysiology of schizophrenia.

  21438146   Dysfunctional gene splicing as a potential contributor to neuropsychiatric disorders.

  21483435   Meta-analysis indicates that common variants at the DISC1 locus are not associated with schizophrenia.

  21642004   DISC1 is associated with cortical thickness and neural efficiency.

  21853134   Sequencing of DISC1 pathway genes reveals increased burden of rare missense variants in schizophrenia patients from a northern Swedish population.

  21878470   Effect of DISC1 on the P300 waveform in psychosis.

  22099458   Common DISC1 polymorphisms disrupt Wnt/GSK3β signaling and brain development.

  22615702   Imaging-genetics in autism spectrum disorder: advances, translational impact, and future directions.

  22723785   DISC1 and Striatal Volume: A Potential Risk Phenotype For mental Illness.

  23140672   DISC1 (disrupted-in-schizophrenia 1) is associated with cortical grey matter volumes in the human brain: a voxel-based morphometry (VBM) study.

  23283688   Common variants in psychiatric risk genes predict brain structure at birth.

  23389941   DISC1 in adult ADHD patients: an association study in two European samples.

  23602339   Human brain imaging studies of DISC1 in schizophrenia, bipolar disorder and depression: a systematic review.

  23732877   708 Common and 2010 rare DISC1 locus variants identified in 1542 subjects: analysis for association with psychiatric disorder and cognitive traits.

  25012417   No evidence of DISC1-associated morphological changes in the hippocampus, anterior cingulate cortex, or striatum in major depressive disorder cases and healthy controls.

  25043320   DISC1-TSNAX and DAOA genes in major depression and citalopram efficacy.

  25529856   Genetic variability testing of neurodevelopmental genes in schizophrenic patients.

  26209938   Variations in Disrupted-in-Schizophrenia 1 gene modulate long-term longitudinal differences in cortical thickness in patients with a first-episode of psychosis.

  26443054   Effect of DISC1 polymorphisms on the long-term course of neurocognitive deficits in non-affective psychosis.

  27023224   Association of DISC1 polymorphisms with late-onset Alzheimer's disease in Northern Han Chinese.

  27369464   Additive sex-specific influence of common non-synonymous DISC1 variants on amygdala, basal ganglia, and white cortical surface area in healthy young adults.

  30324622   DISC1 gene polymorphisms and the risk of schizophrenia in an Iranian population: A preliminary study.

  31264367   Disrupted-in-schizophrenia 1 functional polymorphisms and D(2) /D(3) receptor availability: A [(11) C]-(+)-PHNO imaging study.

  35140610   Genetic Factors Associated With Tardive Dyskinesia: From Pre-clinical Models to Clinical Studies.