Normal allele: GG
A breakdown responsible for the production of the enzyme transketolase, which is involved in the regulation of multiple cancer-related events such as cancer cell proliferation, metastasis, invasion, and resistance to chemoradiation therapy. Indications are high doses of thiamine (vitamin B1), which may normalise the enzyme.
Polymorphism rs4687718 is related to topics like this:
Research and publications:
21076409 Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction.