Normal allele: TT
Increased risk of islet autoimmunity and type 1 diabetes.
Polymorphism rs425105 is related to topics like this:
Research and publications:
20587799 Genetics of type 1 diabetes: what next?
20805105 Synthetic associations in the context of genome-wide association scan signals
21270831 Association between type 1 diabetes and GWAS SNPs in the southeast US Caucasian population.
21980299 A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci.
22190364 Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.
22278338 Confirmation of novel type 1 diabetes risk loci in families.