SNP information rs41295061

Research and publications:

  17676041   Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes.

  18556337   Impact of diabetes susceptibility loci on progression from pre-diabetes to diabetes in at-risk individuals of the diabetes prevention trial-type 1 (DPT-1)

  18776148   Joint genetic susceptibility to type 1 diabetes and autoimmune thyroiditis: from epidemiology to mechanisms

  19106270   Genetic association between the interleukin-2 receptor-alpha gene and mode of onset of type 1 diabetes in the Japanese population.

  19116909   Association of the IL2RA/CD25 gene with juvenile idiopathic arthritis.

  19119414   IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production

  19125193   IL2RA/CD25 gene polymorphisms: uneven association with multiple sclerosis (MS) and type 1 diabetes (T1D).

  19265545   Contrasting genetic association of IL2RA with SLE and ANCA-associated vasculitis.

  19794070   A cis-acting regulatory variant in the IL2RA locus.

  19956099   The type I diabetes association of the IL2RA locus.

  19956106   Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families.

  20033399   Single-nucleotide polymorphisms in the IL2RA gene are associated with age at diagnosis in late-onset Finnish type 1 diabetes subjects.

  20179739   Polymorphisms in the IL2, IL2RA and IL2RB genes in multiple sclerosis risk.

  20236493   The contribution of genetic variation and infection to the pathogenesis of ANCA-associated systemic vasculitis.

  20849903   Association of IL-2RA/CD25 with type 1 diabetes in the Belgian population.

  21179116   An autoimmune-associated variant in PTPN2 reveals an impairment of IL-2R signaling in CD4(+) T cells.

  21815908   The Il2raâ/âCd25 gene variant, which predisposes to Graves' disease, is associated with increased levels of soluble interleukin-2 receptor.

  21875375   Study of polymorphisms in 4q27, 10p15, and 22q13 regions in autoantibodies stratified type 1 diabetes patients.

  22654554   Immunogenetic mechanisms leading to thyroid autoimmunity: recent advances in identifying susceptibility genes and regions.

  26249556   Association of common polymorphisms in the IL2RA gene with type 1 diabetes: evidence of 32,646 individuals from 10 independent studies.

  27014188   Analysis of genetic susceptibility to Graves' disease in a cohort of patients of Italian origin.

  28922436   Genetic Risk Factors for Autoimmune Thyroid Disease might Affect the Susceptibility to and Modulate the Progression of Primary Biliary Cholangitis.