SNP information rs396991

Research and publications:

  12975461   Two immunoglobulin G fragment C receptor polymorphisms independently predict response to rituximab in patients with follicular lymphoma.

  16609067   FCGR3A gene polymorphisms may correlate with response to frontline R-CHOP therapy for diffuse large B-cell lymphoma.

  17704420   FCGR2A and FCGR3A polymorphisms associated with clinical outcome of epidermal growth factor receptor expressing metastatic colorectal cancer patients treated with single-agent cetuximab.

  18347005   Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer.

  18759263   Features associated with, and the impact of, hemolytic anemia in patients with systemic lupus erythematosus: LX, results from a multiethnic cohort.

  19018870   The FCGR3A-158V/F polymorphism may correlate with immunoglobulin levels in patients with non-Hodgkin's lymphoma after treatment with rituximab as an adjuvant to autologous stem cell transplantation.

  19140833   Linkage and association study of FcgammaR polymorphisms in celiac disease.

  19421223   Fcgamma receptors: structure, function and role as genetic risk factors in SLE.

  19640933   FCGR2B gene polymorphism rather than FCGR2A, FCGR3A and FCGR3B is associated with anti-GBM disease in Chinese.

  20018222   Association of polymorphism in FcGR3A gene and progression of low-grade precursor lesions of cervical carcinoma.

  20149216   Fcgamma receptor polymorphisms and their association with periodontal disease: a meta-analysis.

  20392289   Genetic associations in type I interferon related pathways with autoimmunity.

  20400988   A single-nucleotide polymorphism of the Fcγ receptor type IIIA gene in the recipient predicts transplant outcomes after HLA fully matched unrelated BMT for myeloid malignancies.

  20439102   Analysis of MIF, FCGR2A and FCGR3A gene polymorphisms with susceptibility to pulmonary tuberculosis in Moroccan population.

  20508037   Copy number, linkage disequilibrium and disease association in the FCGR locus.

  21060334   Genetic susceptibility to systemic lupus erythematosus in the genomic era.

  21109570   FcγR2A and 3A polymorphisms predict clinical outcome of trastuzumab in both neoadjuvant and metastatic settings in patients with HER2-positive breast cancer.

  21208440   Polymorphisms of Fcγ receptors CD16A and CD32 and circulating immune complexes in Meniere's disease: a case-control study.

  21658613   Host genetics in follicular lymphoma.

  21723269   Genetic profiling of GSTP1, DPYD, FCGR2A, FCGR3A and CCND1 genes in an Argentinian population.

  21980439   A systems genetics approach provides a bridge from discovered genetic variants to biological pathways in rheumatoid arthritis.

  22087647   Replicated associations of TNFAIP3, TNIP1 and ETS1 with systemic lupus erythematosus in a southwestern Chinese population.

  22117530   Pharmacogenetic profiling and cetuximab outcome in patients with advanced colorectal cancer.

  22417159   DNA sequence variation and regulation of genes involved in pathogenesis of pulmonary tuberculosis.

  22486600   Multifactorial pharmacogenetic analysis in colorectal cancer patients receiving 5-fluorouracil-based therapy together with cetuximab-irinotecan.

  22654485   Role of cytokines in systemic lupus erythematosus: recent progress from GWAS and sequencing.

  22879986   Association of Fcγ receptor IIB polymorphism with cryptococcal meningitis in HIV-uninfected Chinese patients.

  22922574   Fcγ receptor polymorphisms do not predict response to intravenous immunoglobulin in myasthenia gravis.

  22992668   Pharmacogenomics knowledge for personalized medicine.

  23075294   Association of the FCGR3A-158F/V gene polymorphism with the response to rituximab treatment in Spanish systemic autoimmune disease patients.

  23251581   Meta-analysis of 125 rheumatoid arthritis-related single nucleotide polymorphisms studied in the past two decades.

  23296156   Role of immunoglobulin G fragment C receptor polymorphism-mediated antibody-dependant cellular cytotoxicity in colorectal cancer treated with cetuximab therapy.

  23649770   Associations between FCGR2A rs1801274, FCGR3A rs396991, FCGR3B NA1/NA2 polymorphisms and periodontitis: a meta-analysis.

  24033266   A systematic approach to assessing the clinical significance of genetic variants.

  24061201   A novel specific pyrosequencing method for genotyping FCGR3A rs396991 without coamplification of homologous gene FCGR3B.

  24136464   Targeted candidate gene resequencing identifies novel variants associated with severe Bechsche uveitis.

  25116105   Human FcR polymorphism and disease.

  25294155   A comprehensive evaluation of the role of genetic variation in follicular lymphoma survival.

  26314337   FCGR2A, FCGR3A, FCGR3B polymorphisms and susceptibility to rheumatoid arthritis: a meta-analysis.

  26367501   Accurate interrogation of FCGR3A rs396991 in European and Asian populations using a widely available TaqMan genotyping method.

  26510856   Fc Gamma Receptor 3A and 2A Polymorphisms Do Not Predict Response to Rituximab in Follicular Lymphoma.

  26785902   Distribution of FcγR gene polymorphisms among two sympatric populations in Mali: differing allele frequencies, associations with malariometric indices and implications for genetic susceptibility to malaria.

  26861312   Association between Genetic Polymorphisms and Response to Anti-TNFs in Patients with Inflammatory Bowel Disease.

  26909137   Evaluation of antibody-dependent cell-mediated cytotoxicity activity and cetuximab response in KRAS wild-type metastatic colorectal cancer patients.

  27092776   A Combination of CD28 (rs1980422) and IRF5 (rs10488631) Polymorphisms Is Associated with Seropositivity in Rheumatoid Arthritis: A Case Control Study.

  27179112   Fc-γ Receptor Polymorphisms, Cetuximab Therapy, and Survival in the NCIC CTG CO.17 Trial of Colorectal Cancer.

  27282998   FCGR3A/2A polymorphisms and diffuse large B-cell lymphoma outcome treated with immunochemotherapy: a meta-analysis on 1134 patients from two prospective cohorts.

  27287460   Perinatal HIV-1 transmission: Fc gamma receptor variability associates with maternal infectiousness and infant susceptibility.

  27338556   SNPs rs4656317 and rs12071048 located within an enhancer in FCGR3A are in strong linkage disequilibrium with rs396991 and influence NK cell-mediated ADCC by transcriptional regulation.

  27417569   Systematic review: genetic biomarkers associated with anti-TNF treatment response in inflammatory bowel diseases.

  27538381   Comprehensive Assessment of the Association between FCGRs polymorphisms and the risk of systemic lupus erythematosus: Evidence from a Meta-Analysis.

  27609290   No association between FCGR2A and FCGR3A polymorphisms in Guillain-Barré Syndrome in a Brazilian population.

  27693588   Genetics of human lupus nephritis.

  27897268   Germline polymorphisms as biomarkers of tumor response in colorectal cancer patients treated with anti-EGFR monoclonal antibodies: a systematic review and meta-analysis.

  27909648   Fcγ Receptors in Solid Organ Transplantation.

  28913867   Effects of FCGRIIIa-158V/F polymorphism on antibody-dependent cellular cytotoxicity activity of adalimumab.

  29155175   FCGR2A single nucleotide polymorphism confers susceptibility to childhood-onset idiopathic nephrotic syndrome.

  29305595   Frequency analysis of the g.7081T>G/A and g.10872T>G polymorphisms in the FCGR3A gene (CD16A) using nested PCR and their functional specific effects.

  29333082   A FCGR3A Polymorphism Predicts Anti-drug Antibodies in Chronic Inflammatory Bowel Disease Patients Treated With Anti-TNF.

  29478298   Functional Fc gamma receptor gene polymorphisms and donor-specific antibody-triggered microcirculation inflammation.

  29555961   Analysis of the relationship between Fc receptor family gene polymorphisms and Behçet's eye disease in Han Chinese.

  30318772   Fc-gamma receptor polymorphisms, cetuximab therapy, and overall survival in the CCTG CO.20 trial of metastatic colorectal cancer.

  30457672   FCGR2A/FCGR3A Gene Polymorphisms and Clinical Variables as Predictors of Response to Tocilizumab and Rituximab in Patients With Rheumatoid Arthritis.

  30636352   Functional and clinical consequences of changes to natural killer cell phenotypes driven by chronic cytomegalovirus infections.

  30659276   Correction: The influence of FCGR2A and FCGR3A polymorphisms on the survival of patients with recurrent or metastatic squamous cell head and neck cancer treated with cetuximab.

  30887566   Association of Fc gamma-receptor genes polymorphisms with chronic periodontitis and Peri-Implantitis.

  31249568   FCGR3A and FCGR2A genotypes have different effects on allograft rejection and patient survival after lung transplantation.

  31342641   Single-nucleotide polymorphisms associated with pemphigus vulgaris: Potent markers for better treatment and personalized medicine.

  31842762   FcγRIIIa receptor polymorphism influences NK cell mediated ADCC activity against HIV.

  32235430   A Comparative Analysis of CD32A and CD16A Polymorphisms in Relation to Autoimmune Responses in Pemphigus Diseases and Subepithelial Autoimmune Blistering Disorders.

  32323406   Effects of intravenous immunoglobulin therapy and Fc gamma receptor polymorphisms on BK virus nephropathy in kidney transplant recipients.

  32484314   Fc-gamma IIIa-V158F receptor polymorphism contributes to the severity of Guillain-Barré syndrome.

  32936528   Important Pharmacogenetic Information for Drugs Prescribed During the SARS-CoV-2 Infection (COVID-19).

  33043529   Evidence for altered host genetic factors in KSHV infection and KSHV-related disease development.

  34145770   Pharmacogenetic variants of infliximab response in young patients with inflammatory bowel disease.

  34207385   Influence of the FCGR2A rs1801274 and FCGR3A rs396991 Polymorphisms on Response to Abatacept in Patients with Rheumatoid Arthritis.

  35149195   The FCGR2A rs1801274 polymorphism was associated with the risk of death among COVID-19 patients.

  35203703   FCGR2A-HH gene variants encoding Fc C-reactive protein receptor gamma are associated with increased monocyte CD32 expression and recurrent cardiovascular events after primary acute coronary syndrome.

  35629038   Searching for New Genetic Biomarkers of Axial Spondyloarthritis.

  35632480   Correlation of Fc Receptor Polymorphisms with Pneumococcal Antibodies in Vaccinated Kidney Transplant Recipients.

  35936668   PD-L1 Amino Acid Position 88 Represents a Hotspot for PD-L1 Stability With Relevance for PD-L1 Inhibition.