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SNP information rs3865444

RS3865444

Normal allele: CC

Association of the CD33 rs3865444 polymorphism with Alzheimer's disease pathology and CD33 expression in human cerebral cortex.

Polymorphism rs3865444 is related to topics like this:

Dementia is genetic

Dementia is characterized as a syndrome, rather than a singular disease. Individuals with early...

Alzheimer's disease is hereditary

Alzheimer's disease is a degenerative brain disease that causes dementia, resulting in a gradual...


Research and publications:

  21460840   Common variants ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.

  21460841   Common variants MS4A4/MS4A6E, CD2AP, CD33, and EPHA1 are associated with late-onset Alzheimer's disease.

  21798052   Replication of the associations of EPHA1 and CD33 with late-onset Alzheimer's disease: a multicenter case-control study.

  22047634   Alzheimer's Disease Neuroimaging Initiative: A review of articles published since its inception.

  22159054   A comprehensive genetic association study of Alzheimer disease in African Americans.

  22380508   Cognitive reserve, cortical plasticity, and resistance to Alzheimer's disease.

  22382309   Prevalence of CD33 and MS4A6A variant in a Chinese Han population with Alzheimer's disease.

  22595970   Identification of cis-regulatory variation influencing protein abundance levels in human plasma.

  22833209   Genome-wide association study identifies multiple novel loci associated with disease progression in subjects with mild cognitive impairment.

  23232270   Association of GWAS-associated loci with late-onset Alzheimer's disease in a Northern Han Chinese population.

  23573206   Genetic loci associated with Alzheimer's disease and cerebrospinal fluid biomarkers in a Finnish case-control cohort.

  23708142   Alzheimer's disease CD33 locus: altered monocyte function and amyloid biology.

  24176626   Evaluation of late-onset Alzheimer disease genetic susceptibility risks in a Canadian population.

  24381305   CD33: Increased inclusion of exon 2 implicates the Ig V-set domain in Alzheimer's disease susceptibility.

  24788522   Genome-wide genetic variation at the CELF1 locus (CUGBP, elav-like family member 1 gene) is associated with Alzheimer's disease and obesity.

  24987407   eMERGEing progress in genomics-the first seven years.

  25108264   Genomics in neurological disorders.

  25186233   The CD33 rs3865444 polymorphism promotes susceptibility to Alzheimer's disease in Chinese, European, and North American populations.

  25188341   Genome-wide association meta-analysis of the neuropathological features of Alzheimer's disease and related dementias.

  25426068   Bioenergetic dysfunction and inflammation in Alzheimer's disease: a possible link.

  25448602   Association of CD33 rs3865444 polymorphism with Alzheimer's disease pathology and CD33 expression in the human cerebral cortex.

  25649863   Identifying genetic interactions associated with late-onset Alzheimer's disease.

  25668194   Examination of candidate exonic variants for association to Alzheimer disease in the Amish.

  25670335   Association of GWAS loci of Alzheimer's disease with MRI markers of brain aging.

  25762156   Genetics of CD33 in Alzheimer's disease and acute myeloid leukemia.

  26438529   Genetics draws attention to microglial inflammation in Alzheimer's disease.

  26449541   Interaction between CLU and MS4A4E variants modulates Alzheimer's disease risk.

  26455864   Association of CD33 and MS4A cluster variants with Alzheimer's disease in East Asian populations.

  26621708   Human-specific derived alleles of CD33 and other genes protect against postreproductive cognitive decline.

  26680604   Polygenic analysis of late-onset Alzheimer's disease in mainland China.

  26795201   Associations Between Genetic Variants in 19p13 and 19q13 Regions and Susceptibility to Alzheimer Disease: A Meta-Analysis.

  26919393   Alzheimer's disease risk polymorphisms regulate gene expression at the ZCWPW1 and CELF1 loci.

  26933222   Alzheimer's disease CD33 variant rs3865444 does not promote cognitive function.

  26993346   Genetic risk factors for posterior cortical atrophy variant of Alzheimer's disease.

  27274215   Genes associated with Alzheimer's disease: review and current status.

  27313629   Modeling Alzheimer's disease using induced pluripotent stem cells: current issues and future challenges.

  27407070   Obtaining Human Ischemic Stroke Gene Expression Biomarkers from Animal Models: A Cross-species Validation Study.

  27453991   A new approach to multi-SNP GWAS and its application in Alzheimer's disease.

  27504496   Trans-pQTL study identifies immune crosstalk between Parkinson and Alzheimer loci.

  27610127   Analysis of heterogeneous multimodal biomarkers of Alzheimer's disease using a Bayesian network.

  27781389   Genetic variants associated with Alzheimer's disease risk contribute to cognitive changes in midlife: Atherosclerosis Risk in Communities Study.

  28084078   Association of major GWAS genes with late-onset Alzheimer's disease in a Colombian population.

  28477215   Validation of GWAS variants from microglial genes involved in Alzheimer's disease.

  28549481   The genetics of late-onset Alzheimer's disease implicates microglial pathways in disease risk.

  29872490   Genome-wide significant risk factors on chromosome 19 and the APOE locus.

  29951491   Meta-analysis of the association between CD33 and Alzheimer's disease.

  30619483   Genetic Variants Associated With Neurodegenerative Diseases Regulate Gene Expression in Immune Cell CD14+ Monocytes.

  30883353   Effects of CD33 Variants on Neuroimaging Biomarkers in Non-Demented Elders.

  31054508   Cognitive performance associated with CD33 genotype was bidirectionally modulated by intrinsic functional connectivity across the Alzheimer's disease spectrum.

  31473137   Genome-wide association analysis of dementia and its clinical endophenotypes identifies novel loci associated with Alzheimer's disease and three causal networks: the GR@ACE project.

  31799158   Association of MS4A6A, CD33 and TREM2 gene polymorphisms with late-onset Alzheimer's disease.

  32088842   Does CD33 rs3865444 polymorphism confer susceptibility to Alzheimer's disease?

  32333488   The association of the CD33 rs3865444:CËA polymorphism with a reduced risk of late-onset Alzheimer's disease in Slovaks is limited to subjects carrying the APOE β4 allele.

  33198164   Multiple Sclerosis: Shall We Target CD33?

  33254494   Common determinants of severe Covid-19 infection are explicable by SARS-CoV-2 secreted glycoprotein interaction with the CD33-related Siglecs, Siglec-3 and Siglec-5/14.

  33582190   CD33 rs3865444 as a risk factor for Parkinson's disease.

  33815092   Genetic variation in molecular pathways associated with Alzheimer's disease: a comprehensive review.

  34371203   Unraveling the vast literature to uncover the genetic basis of Alzheimer's disease: a systematic review and meta-analysis.

  34569532   CD33 mRNA has increased levels of expression in peripheral blood leukocytes of patients with late-onset Alzheimer's disease.

  34975449   Structural covariance network as an endophenotype in Alzheimer's disease susceptibility single nucleotide polymorphisms and correlations with cognitive outcomes.

  34977040   Gene-Based Testing of Interactions Using XGBoost in Genome-Wide Association Studies.

  35124268   Mendelian Randomization Analysis Reveals No Causal Relationship Between Nonalcoholic Fatty Liver Disease and Severe COVID-19.

  35436980   Allele-specific analysis reveals exon- and cell-type-specific regulatory effects of genetic variants associated with Alzheimer's disease.

  35888182   Alzheimer's disease risk variant rs3865444 in the CD33 gene: possible role in susceptibility to multiple sclerosis.

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