SNP information rs33980500

Research and publications:

  20652909   A custom 148 gene-based resequencing chip and the SNP explorer software: new tools to study antibody deficiency.

  20953186   Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis.

  20953188   Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2.

  22445837   TRAF3IP2 gene is associated with cutaneous extraintestinal manifestations in inflammatory bowel disease.

  22513239   Identification of low-frequency TRAF3IP2 coding variants in psoriatic arthritis patients and functional characterization.

  22581863   CIKS/Act1-mediated signaling by IL-17 cytokines in context: implications for how a CIKS gene variant may predispose to psoriasis.

  22988944   Network-based SNP meta-analysis identifies joint and disjoint genetic features across common human diseases.

  23116200   New insight into the functions of the interleukin-17 receptor adaptor protein Act1 in psoriatic arthritis.

  23836313   TRAF3IP2 gene and systemic lupus erythematosus: association with disease susceptibility and pericarditis development.

  23886662   A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis.

  24005976   Common variants of ZNF750, RPTOR and TRAF3IP2 genes and psoriasis risk.

  24033266   A systematic approach to assessing the clinical significance of genetic variants.

  24069534   Genetics of psoriasis and pharmacogenetics of biological drugs.

  24120361   An ACT1 mutation selectively abolishes interleukin-17 responses in humans with chronic mucocutaneous candidiasis.

  24175098   The role of 39 psoriasis risk variants on age of psoriasis onset.

  25024377   The differential regulation of human ACT1 isoforms by Hsp90 in IL-17 signaling.

  25233071   Allele-specific network reveals combinatorial interaction that transcends small effects in psoriasis GWAS.

  25651891   Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis.

  26255310   Identifying a novel locus for psoriatic arthritis.

  26613086   Polymorphisms Associated with Age at Onset in Patients with Moderate-to-Severe Plaque Psoriasis.

  26798662   Genetic Factors in Systemic Lupus Erythematosus: Contribution to Disease Phenotype.

  27810495   Psoriasis risk SNPs and their association with HIV-1 control.

  28107378   Polymorphisms in STAT4, PTPN2, PSORS1C1 and TRAF3IP2 Genes Are Associated with the Response to TNF Inhibitors in Patients with Rheumatoid Arthritis.

  29302052   The Act1 D10N missense variant impairs CD40 signaling in human B-cells.

  29430728   Plasma CXCL1 levels and TRAF3IP2 variants in patients with myocardial infarction.

  30511928   Development and application of a PCR-HRM molecular diagnostic method of SNPs linked with TNF inhibitor efficacy.

  30528823   Neutrophil Extracellular Traps Induce Human Th17 Cells: Effect of Psoriasis-Associated TRAF3IP2 Genotype.

  31577850   Paradoxical psoriasis induced by TNF-α blockade shows immunological features typical of the early phase of psoriasis development.

  32778885   Using functional genomics to advance the understanding of psoriatic arthritis.

  35642993   A multilocus genetic study evidences the association of autoimmune-related genes with Psoriatic Arthritis in Italian patients.