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SNP information rs2981579

RS2981579

Normal allele: GG

FGFR2 gene variation and the effect of low-fat diet on invasive breast cancer.

Polymorphism rs2981579 is related to topics like this:

BRCA gene

BRCA stands for "BReast CAncer gene" and refers to two distinct genes, BRCA1 and BRCA2, which have...


Research and publications:

  17529973   A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer.

  18285324   Common variation in the fibroblast growth factor receptor 2 gene is not associated with endometriosis risk.

  18326623   Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33.

  18483326   FGFR2 is a breast cancer susceptibility gene in Jewish and Arab Israeli populations.

  19330030   A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1).

  19497954   Histone-acetylated control of fibroblast growth factor receptor 2 intron 2 polymorphisms and isoform splicing in breast cancer.

  19500394   Genetic variants of the FGFR2 and FGFR4 genes and skin cancer risk in the Nurses' Health Study.

  19789366   Evaluation of 11 breast cancer susceptibility loci in African-American women.

  19861516   Variation in the FGFR2 gene and the effects of postmenopausal hormone therapy on invasive breast cancer.

  20056625   Variation in the FGFR2 gene and the effect of a low-fat dietary pattern on invasive breast cancer.

  20453838   Genome-wide association study identifies five new breast cancer susceptibility loci.

  20554749   FGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger women.

  20853316   FGFR2 intronic SNPs and breast cancer risk: associations with tumor characteristics and interactions with exogenous exposures and other known breast cancer risk factors.

  21445572   Genetic polymorphisms and breast cancer risk: evidence from meta-analyses, pooled analyses, and genome-wide association studies.

  21610108   A multistage association study identifies a breast cancer genetic locus at NCOA7.

  21655367   In search of breast cancer culprits: suspecting the suspected and the unsuspected.

  21695280   Pathways of distinction analysis: a new technique for multi-SNP analysis of GWAS data.

  21702935   Genetic variants in the MRPS30 region and postmenopausal breast cancer risk.

  21795501   Replication of GWAS breast cancer susceptibility loci in the Women's Health Initiative African American SHARe Study.

  21853025   A bayesian method for evaluating and discovering disease loci associations.

  21869864   An integrative genomics approach to biomarker discovery in breast cancer.

  21949660   Genetic variants at chromosomes 2q35, 5p12, 6q25.1, 10q26.13, and 16q12.1 influence the risk of breast cancer in men.

  22160591   A genetic risk predictor for breast cancer using a combination of low-penetrance polymorphisms in a Japanese population.

  22303333   Replication of GWAS "Hits" by Race for Breast and Prostate Cancers in European Americans and African Americans.

  22452962   A genome-wide association study identifies a breast cancer risk variant in ERBB4 at 2q34: results from the Seoul Breast Cancer Study.

  22734045   Identifying genetic marker sets associated with phenotypes via an efficient adaptive score test.

  22747683   Genetic variants associated with breast size also influence breast cancer risk.

  22806168   A multistage genetic association study identifies breast cancer risk loci at 10q25 and 16q24.

  22965832   Association of common genetic variants with breast cancer risk and clinicopathological characteristics in a Chinese population.

  23124475   Three novel functional polymorphisms in the promoter of FGFR2 gene and breast cancer risk: a HuGE review and meta-analysis.

  23136140   Genetic susceptibility loci for subtypes of breast cancer in an African American population.

  23354978   Genetic variants associated with breast cancer risk for Ashkenazi Jewish women with strong family histories but no identifiable BRCA1/2 mutation.

  23519603   Variable selection and estimation in generalized linear models with the seamless L(0) penalty.

  23717390   Identification of a breast cancer susceptibility locus at 4q31.22 using a genome-wide association study paradigm.

  24025454   Hereditary breast cancer: ever more pieces to the polygenic puzzle.

  24218030   Replication of breast cancer susceptibility loci in whites and African Americans using a Bayesian approach.

  24266904   Breast cancer prediction using genome wide single nucleotide polymorphism data.

  24340245   Adiposity, inflammation, genetic variants and risk of post-menopausal breast cancer findings from a prospective-specimen-collection, retrospective-blinded-evaluation (PRoBE) design approach.

  24359602   Common breast cancer risk variants in the post-COGS era: a comprehensive review.

  24454457   Case-control study on the fibroblast growth factor receptor 2 gene polymorphisms associated with breast cancer in chinese han women.

  24743323   Genetic predisposition to in situ and invasive lobular carcinoma of the breast.

  24771903   Breast Cancer Risk - From Genetics to Molecular Understanding of Pathogenesis.

  24832084   Cross-cancer pleiotropic analysis of endometrial cancer: PAGE and E2C2 consortia.

  24941967   Breast cancer risk assessment using genetic variants and risk factors in a Singapore Chinese population.

  25285046   Graphical-model Based Multiple Testing under Dependence, with Applications to Genome-wide Association Studies.

  25677745   Rationale for targeting fibroblast growth factor receptor signaling in breast cancer.

  25788325   Evaluation of a two-stage framework for prediction using big genomic data.

  25956309   Genome-wide association study of susceptibility loci for breast cancer in Sardinian population.

  26157456   Using parental phenotypes in case-parent studies.

  26175953   FGFR2 gene polymorphisms are associated with breast cancer risk in the Han Chinese population.

  26421298   Heterogeneity of Breast Cancer Associations with Common Genetic Variants in FGFR2 according to the Intrinsic Subtypes in Southern Han Chinese Women.

  26510858   Patients with a High Polygenic Risk of Breast Cancer do not have An Increased Risk of Radiotherapy Toxicity.

  26728143   Variants of FGFR2 and their associations with breast cancer risk: a HUGE systematic review and meta-analysis.

  26866629   Using family members to augment genetic case-control studies of a life-threatening disease.

  26884359   Genetic predisposition to ductal carcinoma in situ of the breast.

  27392074   The Relationship between Common Genetic Markers of Breast Cancer Risk and Chemotherapy-Induced Toxicity: A Case-Control Study.

  27424552   Genomics era and complex disorders: Implications of GWAS with special reference to coronary artery disease, type 2 diabetes mellitus, and cancers.

  27449795   Shared and unique common genetic determinants between pediatric and adult celiac disease.

  27708667   Admixture Mapping of African-American Women in the AMBER Consortium Identifies New Loci for Breast Cancer and Estrogen-Receptor Subtypes.

  27814745   Deep targeted sequencing of 12 breast cancer susceptibility regions in 4611 women across four different ethnicities.

  27825120   Trans-ethnic follow-up of breast cancer GWAS hits using the preferential linkage disequilibrium approach.

  27848153   Previous GWAS hits in relation to young-onset breast cancer.

  28098224   Association of Genome-Wide Association Study (GWAS) Identified SNPs and Risk of Breast Cancer in an Indian Population.

  28235418   BaalChIP: Bayesian analysis of allele-specific transcription factor binding in cancer genomes.

  29104507   Fibroblast Growth Factor Receptor 2 Signaling in Breast Cancer.

  29390357   Association between rs11200014, rs2981579, and rs1219648 polymorphism and breast cancer susceptibility: A meta-analysis.

  29560110   Evaluation of three polygenic risk score models for the prediction of breast cancer risk in Singapore Chinese.

  29652634   Emerging applications of genome-editing technology to examine functionality of GWAS-associated variants for complex traits.

  30359238   Effects of FGFR gene polymorphisms on response and toxicity of cyclophosphamide-epirubicin-docetaxel-based chemotherapy in breast cancer patients.

  31113874   The association of genetic variants in FGFR2 with osteoporosis susceptibility in Chinese Han population.

  31125336   Evaluation of significant genome-wide association studies risk - SNPs in young breast cancer patients.

  31142340   FGFs/FGFRs-dependent signalling in regulation of steroid hormone receptors - implications for therapy of luminal breast cancer.

  31178825   Endocrine Resistance in Hormone Receptor Positive Breast Cancer-From Mechanism to Therapy.

  32287273   DOT: Gene-set analysis by combining decorrelated association statistics.

  32366738   Low-penetrance susceptibility variants and postmenopausal oestrogen receptor positive breast cancer.

  33081025   The FGF/FGFR System in Breast Cancer: Oncogenic Features and Therapeutic Perspectives.

  33112566   The Associations of Common Genetic Susceptibility Variants with Breast Cancer in Jordanian Arabs: A Case-Control Study.

  33632172   Discovery of breast cancer risk genes and establishment of a prediction model based on estrogen metabolism regulation.

  34359697   A Personal Breast Cancer Risk Stratification Model Using Common Variants and Environmental Risk Factors in Japanese Females.

  34514747   Activation of FGFR2 Signaling Suppresses BRCA1 and Drives Triple-Negative Mammary Tumorigenesis That is Sensitive to Immunotherapy.

  34759736   Fibroblast growth factor receptor 2 gene (FGFR2) rs2981582T/C polymorphism and susceptibility to breast cancer in Saudi women.

  35176995   Exploring the effects of genetic variation on gene regulation in cancer in the context of 3D genome structure.

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