SNP information rs2981578

Research and publications:

  17529967   Genome-wide association study identifies novel breast cancer susceptibility loci.

  18285324   Common variation in the fibroblast growth factor receptor 2 gene is not associated with endometriosis risk.

  18462018   Allele-specific up-regulation of FGFR2 increases susceptibility to breast cancer.

  19223389   FGFR2 variants and breast cancer risk: fine-scale mapping using African American studies and analysis of chromatin conformation.

  19434427   Analytical methods for inferring functional effects of single base pair substitutions in human cancers.

  19497954   Histone-acetylated control of fibroblast growth factor receptor 2 intron 2 polymorphisms and isoform splicing in breast cancer.

  19519208   Polygenic susceptibility to breast cancer: current state-of-the-art.

  19536173   Association of FGFR2 gene polymorphisms with the risk of breast cancer in population of West Siberia.

  19789366   Evaluation of 11 breast cancer susceptibility loci in African-American women.

  19861516   Variation in the FGFR2 gene and the effects of postmenopausal hormone therapy on invasive breast cancer.

  20193855   rs2981582 is associated with FGFR2 expression in normal breast.

  20348248   Genetic and epigenetic mechanisms down-regulate FGF receptor 2 to induce melanoma-associated antigen A in breast cancer.

  20453838   Genome-wide association study identifies five new breast cancer susceptibility loci.

  20554749   FGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger women.

  20650817   Functional intronic polymorphisms: Buried treasure awaiting discovery within our genes.

  21102626   Caution in generalizing known genetic risk markers for breast cancer across all ethnic/racial populations.

  21418638   FGFR2 protein expression in breast cancer: nuclear localisation and correlation with patient genotype.

  21541012   Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium.

  21767389   Allele-specific regulation of FGFR2 expression is cell type-dependent and may increase breast cancer risk through a paracrine stimulus involving FGF10.

  21822685   Genetic variants of fibroblast growth factor receptor 2 (FGFR2) are associated with breast cancer risk in Chinese women of the Han nationality.

  21852243   Fine-mapping of breast cancer susceptibility loci characterizes genetic risk in African Americans.

  22287734   Evaluation of breast cancer susceptibility loci on 2q35, 3p24, 17q23 and FGFR2 genes in Taiwanese women with breast cancer.

  22357627   Evaluation of 19 susceptibility loci of breast cancer in women of African ancestry.

  23107584   Identifying breast cancer risk loci by global differential allele-specific expression (DASE) analysis in mammary epithelial transcriptome.

  23124475   Three novel functional polymorphisms in the promoter of FGFR2 gene and breast cancer risk: a HuGE review and meta-analysis.

  24143190   Genome-wide association study of breast cancer in the Japanese population.

  24218030   Replication of breast cancer susceptibility loci in whites and African Americans using a Bayesian approach.

  25333473   A study on genetic variants of Fibroblast growth factor receptor 2 (FGFR2) and the risk of breast cancer from North India.

  25677745   Rationale for targeting fibroblast growth factor receptor signaling in breast cancer.

  26113264   Functional annotation of HOT regions in the human genome: implications for human disease and cancer.

  26157456   Using parental phenotypes in case-parent studies.

  26728143   Variants of FGFR2 and their associations with breast cancer risk: a HUGE systematic review and meta-analysis.

  26866629   Using family members to augment genetic case-control studies of a life-threatening disease.

  27223085   Variants in human papillomavirus receptor and associated genes are associated with type-specific HPV infection and lesion progression of the cervix.

  27236187   FGFR2 risk SNPs confer breast cancer risk by augmenting oestrogen responsiveness.

  27708667   Admixture Mapping of African-American Women in the AMBER Consortium Identifies New Loci for Breast Cancer and Estrogen-Receptor Subtypes.

  27814745   Deep targeted sequencing of 12 breast cancer susceptibility regions in 4611 women across four different ethnicities.

  27825120   Trans-ethnic follow-up of breast cancer GWAS hits using the preferential linkage disequilibrium approach.

  28235418   BaalChIP: Bayesian analysis of allele-specific transcription factor binding in cancer genomes.

  29104507   Fibroblast Growth Factor Receptor 2 Signaling in Breast Cancer.

  29382703   Common Genetic Variation and Breast Cancer Risk-Past, Present, and Future.

  29652634   Emerging applications of genome-editing technology to examine functionality of GWAS-associated variants for complex traits.

  30285756   Subtype-specific associations between breast cancer risk polymorphisms and the survival of early-stage breast cancer.

  30359238   Effects of FGFR gene polymorphisms on response and toxicity of cyclophosphamide-epirubicin-docetaxel-based chemotherapy in breast cancer patients.

  31142340   FGFs/FGFRs-dependent signalling in regulation of steroid hormone receptors - implications for therapy of luminal breast cancer.

  31509720   Genetic Polymorphisms in FGFR2 Underlie Skeletal Malocclusion.

  32269954   Copy number alternations of the 17q23-rs6504950 locus are associated with advanced breast cancers in Taiwanese women.

  32287273   DOT: Gene-set analysis by combining decorrelated association statistics.

  32620845   A sequential methodology for the rapid identification and characterization of breast cancer-associated functional SNPs.

  32894086   MassARRAY-based single nucleotide polymorphism analysis in breast cancer of north Indian population.

  33081025   The FGF/FGFR System in Breast Cancer: Oncogenic Features and Therapeutic Perspectives.

  34359697   A Personal Breast Cancer Risk Stratification Model Using Common Variants and Environmental Risk Factors in Japanese Females.

  35395775   Development and validation of polygenic risk scores for prediction of breast cancer and breast cancer subtypes in Chinese women.