Normal allele: TT
The common PTK2B variant is associated with late-onset Alzheimer's disease.
Polymorphism rs28834970 is related to topics like this:
Research and publications:
24443964 Review: Genetics of Alzheimer's disease;
25108264 Genomics in neurological disorders.
25426068 Bioenergetic dysfunction and inflammation in Alzheimer's disease: a possible link.
25668194 Examination of candidate exonic variants for association to Alzheimer disease in the Amish.
26680604 Polygenic analysis of late-onset Alzheimer's disease in mainland China.
26919393 Alzheimer's disease risk polymorphisms regulate gene expression at the ZCWPW1 and CELF1 loci.
26993346 Genetic risk factors for posterior cortical atrophy variant of Alzheimer's disease.
27274215 Genes associated with Alzheimer's disease: review and current status.
27340842 Evaluating a genetic risk score to improve Alzheimer's disease risk prediction.
27453991 A new approach to multi-SNP GWAS and its application in Alzheimer's disease.
27504496 Trans-pQTL study identifies immune crosstalk between Parkinson and Alzheimer loci.
28549481 The genetics of late-onset Alzheimer's disease implicates microglial pathways in disease risk.
33815092 Genetic variation in molecular pathways associated with Alzheimer's disease: a comprehensive review.