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SNP information rs28834970

RS28834970

Normal allele: TT

The common PTK2B variant is associated with late-onset Alzheimer's disease.

Polymorphism rs28834970 is related to topics like this:

Alzheimer's disease is hereditary

Alzheimer's disease is a degenerative brain disease that causes dementia, resulting in a gradual...


Research and publications:

  24443964   Review: Genetics of Alzheimer's disease;

  24495969   Surveillance of the International Alzheimer's Disease Genomics Project loci identified TRIP4 as a novel susceptibility gene.

  24743338   Connecting the dots: the potential of data integration to identify regulatory SNPs in late-onset Alzheimer's disease GWAS results.

  25108264   Genomics in neurological disorders.

  25188341   Genome-wide association meta-analysis of the neuropathological features of Alzheimer's disease and related dementias.

  25426068   Bioenergetic dysfunction and inflammation in Alzheimer's disease: a possible link.

  25668194   Examination of candidate exonic variants for association to Alzheimer disease in the Amish.

  26680604   Polygenic analysis of late-onset Alzheimer's disease in mainland China.

  26919393   Alzheimer's disease risk polymorphisms regulate gene expression at the ZCWPW1 and CELF1 loci.

  26993346   Genetic risk factors for posterior cortical atrophy variant of Alzheimer's disease.

  27080426   A common PTK2B variant is associated with late-onset Alzheimer's disease: a replication study and meta-analysis.

  27274215   Genes associated with Alzheimer's disease: review and current status.

  27313629   Modeling Alzheimer's disease using induced pluripotent stem cells: current issues and future challenges.

  27340842   Evaluating a genetic risk score to improve Alzheimer's disease risk prediction.

  27453991   A new approach to multi-SNP GWAS and its application in Alzheimer's disease.

  27504496   Trans-pQTL study identifies immune crosstalk between Parkinson and Alzheimer loci.

  27662287   Pathway-specific polygenic risk scores as predictors of β-amyloid deposition and cognitive function in a sample at increased risk of Alzheimer's disease.

  28549481   The genetics of late-onset Alzheimer's disease implicates microglial pathways in disease risk.

  30128317   Genetic risk of Alzheimer's disease is reduced in primary age-related tauopathy: a potential model of resistance?

  30144538   Relationships between four loci identified by GWAS in Alzheimer's disease and the risk of Parkinson's disease, amyotrophic lateral sclerosis, and multiple system atrophy.

  31256143   Assessing the association of Alzheimer's disease risk variants that are highly expressed in microglia with measures of neuropathological outcome.

  33815092   Genetic variation in molecular pathways associated with Alzheimer's disease: a comprehensive review.

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