SNP information rs2279590

Research and publications:

  19182256   Exploring functional candidate genes for genetic association in german patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma.

  20570404   Association of CLU and PICALM variants with Alzheimer's disease.

  20594621   Genetic architecture of Alzheimer's disease: beyond APP, PSEN and APOE.

  20599866   Significance of CLU gene polymorphism in Chinese patients with Alzheimer's disease.

  20850846   Association of the clusterin gene polymorphisms with type 2 diabetes mellitus.

  21364909   Eurasian and Sub-Saharan African mitochondrial DNA haplogroup influences pseudoexfoliation glaucoma development in Saudi patients.

  22015308   Polymorphisms of CR1, CLU and PICALM determine susceptibility to Alzheimer's disease in a population of southern China.

  22159054   A comprehensive genetic association study of Alzheimer disease in African Americans.

  22216291   Association between IgM anti-herpes simplex virus and plasma amyloid-beta levels.

  22911757   Association study of candidate gene polymorphisms with amnestic mild cognitive impairment in a Chinese population.

  24947876   The CLU rs2279590 polymorphism promotes susceptibility to Alzheimer's disease in Caucasian and Asian populations.

  24958191   Clusterin variants are not associated with southern Chinese patients with Alzheimer's disease.

  25057782   Role of an extracellular chaperone, Clusterin in the pathogenesis of Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma.

  25633098   The CLU rs9331888 polymorphism promotes susceptibility to Alzheimer's disease in Caucasian but not East Asian populations.

  25849827   Evaluation of genetic polymorphisms in clusterin and tumor necrosis factor-alpha genes in South Indian individuals with pseudoexfoliation syndrome.

  26272660   Association of clusterin (CLU) variants and exfoliation syndrome: An analysis in two Caucasian studies and a meta-analysis.

  26680604   Polygenic analysis of late-onset Alzheimer's disease in mainland China.

  27076484   The Association Between Clusterin and APOE Polymorphisms and Late-Onset Alzheimer Disease in a Turkish Cohort.

  27229352   Impact of CLU genetic variants on cerebrospinal fluid and neuroimaging markers in healthy individuals with mild cognitive impairment and Alzheimer's disease cohorts.

  27274215   Genes associated with Alzheimer's disease: review and current status.

  27882096   Association between clusterin gene rs11136000 polymorphism and susceptibility to late-onset Alzheimer's disease: a review and meta-analysis of case-control studies.

  28973302   The CLU risk variant associated with pseudoexfoliation and Alzheimer's disease, rs2279590, resides within an enhancer element and regulates the expression of the CLU, EPHX2, and PTK2B genes.

  29276745   Frequencies of alleles, genotypes and haplotypes of two polymorphisms in the clusterin gene in the Russian elderly population categorized by cognitive performance.

  31192002   Multiple Gene Polymorphisms Associated with Exfoliation Syndrome in the Uygur Population.

  31341659   CLU Polymorphisms in Patients with Pseudoexfoliation Syndrome in Polish Population.

  32848603   Impacts of AD-Related ABCA7 and CLU Variants on Default Mode Network Connectivity in Healthy Middle-Age Adults.

  32882505   Association between CLU polymorphisms and memory performance: role of serum lipids in Alzheimer's disease.

  33815092   Genetic variation in molecular pathways associated with Alzheimer's disease: a comprehensive review.