SNP information rs2201841

Research and publications:

  17606463   Functional variants of interleukin-23 receptor gene confer risk for rheumatoid arthritis but not for systemic sclerosis.

  17786191   rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: a combined analysis of IL23R, CARD15 and OCTN1/2 variants.

  18073300   Interleukin (IL)-23 receptor is a major susceptibility gene for Graves' ophthalmopathy: the IL-23/T-helper 17 axis extends to thyroid autoimmunity.

  18338763   Association of IL23R, TNFRSF1A, and HLA-DRB1*0103 allele variants with inflammatory bowel disease phenotypes in the Finnish population.

  18383363   Association of interleukin-23 receptor variants with ankylosing spondylitis.

  18470928   IL23R haplotypes confer a high population risk of developing Crohn's disease.

  19021011   Association studies of the IL-23R gene in autoimmune thyroid disease in the Japanese population.

  19034457   Lack of association between interleukin 23 receptor gene polymorphisms and rheumatoid arthritis susceptibility.

  19103559   [Susceptibility genetic variants in Hungarian morbus Crohn and ulcerative colitis patients].

  19169254   Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways.

  19175939   IL23R in the Swedish, Finnish, Hungarian and Italian populations: association with IBD and psoriasis, and linkage to celiac disease.

  19262574   Genome-wide association scan yields new insights into the immunopathogenesis of psoriasis.

  19306001   No association between interleukin 23 receptor gene polymorphisms and systemic lupus erythematosus.

  19522770   Variants of the IL23R gene are associated with ankylosing spondylitis but not with Sjögren syndrome in Hungarian population samples.

  19757086   Interleukin-23 receptor gene variants in Hungarian systemic lupus erythematosus patients.

  20066736   Interaction of major susceptibility alleles to inflammatory bowel disease in patients with Crohn's disease.

  20228799   Genome-wide association identifies multiple ulcerative colitis susceptibility loci.

  20444268   Peripheral blood gene expression patterns discriminate among chronic inflammatory diseases and healthy controls and identify novel targets

  20454450   Evidence that STAT4 is a common autoimmune gene: rs7574865 is associated with Crohn's disease of the colon and early onset of the disease.

  20505004   On safari to Random Jungle: a fast implementation of Random Forests for high-dimensional data.

  20606885   Genetics of psoriasis and psoriatic arthritis.

  20953188   Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2.

  20978829   Polymorphisms of the IL23R gene are associated with psoriasis but not with immunoglobulin A nephropathy in a Hungarian population.

  21090563   Blockade of cytotoxic T-lymphocyte antigen-4 by ipilimumab results in dysregulation of gastrointestinal immunity in patients with advanced melanoma.

  21121902   Detecting epistatic SNPs associated with complex diseases via a Bayesian classification tree search method.

  21246217   BR-squared: a practical solution to the winner's curse problem in genome-wide scanning.

  21253569   Genome-wide association study SNPs in the human genome diversity project populations: does selection affect unlinked SNPs with shared trait associations?

  21304977   An investigation of genome-wide studies reported susceptibility loci for ulcerative colitis shows limited replication in north Indians.

  21427131   Improved Crohn's disease risk prediction using a multilocus approach.

  21559399   CEACAM6 gene variants in inflammatory bowel disease.

  21618365   Distortion of transmission of the Crohn's disease risk gene ATG16L1 leads to sex differences in disease association.

  21682861   Balancing selection is common in the extended MHC region but most alleles with opposite risk profile for autoimmune diseases are neutrally evolving.

  21852963   Pervasive sharing of genetic effects in autoimmune disease.

  22089529   Associations between interleukin-23R polymorphisms and ankylosing spondylitis susceptibility: a meta-analysis.

  22123319   A prospective phase II trial exploring the association between tumor microenvironment biomarkers and clinical activity of ipilimumab in advanced melanoma.

  22190364   Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.

  22242114   The role of osteopontin haplotypes (OPN/SPP1) in susceptibility to Crohn's disease.

  22242199   Genetic factors of autoimmune thyroid diseases in Japanese.

  22269043   Clinical predictors of inflammatory bowel disease in a genetically well-defined Caucasian population.

  22346247   The role of ATG16L, NOD2 and IL23R in the pathogenesis of Crohn's disease.

  22359581   Th17-related genes and celiac disease susceptibility.

  22411504   Contribution of higher risk genes and European admixture to Crohn's disease in African Americans.

  22440928   Perianal Crohn's disease: prognostic factors and genotype-phenotype correlations.

  22457781   Variants in the PTPN2 gene are associated with susceptibility to both Crohn's disease and ulcerative colitis, supporting a common genetic basis for the disease.

  22479607   Analysis of IL12B gene variants in inflammatory bowel disease.

  22654555   Genetic basis of Graves' disease.

  22654556   Graves' ophthalmopathy: a review of immunogenetics.

  22706445   Association of IL23R polymorphisms with psoriasis and psoriatic arthritis: a meta-analysis.

  22984500   Association of single nucleotide polymorphisms of IL23R and IL17 with ulcerative colitis risk in a Chinese Han population.

  23053963   Associations between interleukin-23 receptor polymorphisms and susceptibility to rheumatoid arthritis: a meta-analysis.

  23054009   A diversity of IL23R gene haplotype variants was noted in rheumatoid arthritis compared to Crohn's disease and ankylosing spondylitis.

  23093364   Differences in haplotype variants of the interleukin-23 receptor gene in ulcerative colitis compared with Crohn's disease and psoriasis.

  23300802   Polymorphisms modulating PTGER4 expression in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites.

  23365659   IRGM variants and susceptibility to inflammatory bowel disease in the German population.

  23886662   A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis.

  24069534   Genetics of psoriasis and pharmacogenetics of biological drugs.

  24223725   Intestinal DMBT1 expression is modulated by IL23R variants associated with Crohn's disease and a DMBT1 variant that affects the binding of the transcription factors CREB1 and ATF-2.

  24332578   Marked differences of haplotype tagging SNP distribution, linkage, and haplotype profile of IL23 receptor gene in Roma and Hungarian population samples.

  24547735   Association of IL-23 and its receptor gene single-nucleotide polymorphisms with multiple sclerosis in Chinese southern population.

  24910145   IL-23R gene polymorphism rs2201841 is associated with psoriatic arthritis.

  24957500   Genetic variation at IL12B, IL23R and IL23A is associated with psoriasis severity, psoriatic arthritis and type 2 diabetes mellitus.

  25133031   Genetic update on inflammatory factors in ulcerative colitis: Review of the current literature.

  25497273   Interleukin-23 receptor genetic polymorphisms and ulcerative colitis susceptibility: A meta-analysis.

  25655172   Filter-free exhaustive odds ratio-based genome-wide interaction approach pinpoints evidence for interaction in the HLA region in psoriasis.

  25884002   Phenome-wide Association Study Relating Pretreatment Laboratory Parameters With Human Genetic Variants in AIDS Clinical Trials Group Protocols.

  26040912   The projack: a resampling approach to correct for ranking bias in high-throughput studies.

  26472011   Investigation of association of the IL-12B and IL-23R genetic variations with psoriatic risk in a South Indian Tamil cohort.

  26678098   Association of interleukin-23 receptor gene polymorphisms with susceptibility to Crohn's disease: a meta-analysis.

  26833331   Retrospective Binary-Trait Association Test Elucidates Genetic Architecture of Crohn Disease.

  26861312   Association between Genetic Polymorphisms and Response to Anti-TNFs in Patients with Inflammatory Bowel Disease.

  26943356   Differences in gene interactions in patients with Graves' disease stratified by age of onset.

  27014188   Analysis of genetic susceptibility to Graves' disease in a cohort of patients of Italian origin.

  27153677   Assessing statistical significance in multivariable genome wide association analysis.

  27156530   Genetic variation in IBD: progress, clues to pathogenesis and possible clinical utility.

  27538101   Association of Genetic Variants in Pentraxin 3 Gene with Ankylosing Spondylitis.

  27810495   Psoriasis risk SNPs and their association with HIV-1 control.

  27902482   IL-23R mutation is associated with ulcerative colitis: A systemic review and meta-analysis.

  28210080   IL23R single nucleotide polymorphisms could be either beneficial or harmful in ulcerative colitis.

  28603427   Pharmacogenetics in inflammatory bowel disease: understanding treatment response and personalizing therapeutic strategies.

  29148561   The role of IL-23 receptor signaling in inflammation-mediated erosive autoimmune arthritis and bone remodeling.

  29370888   Lack of association between rheumatoid arthritis and genetic variants rs10889677, rs11209026 and rs2201841 of IL-23R gene.

  29691688   Associations between interleukin-23R polymorphisms and ankylosing spondylitis susceptibility: an updated meta-analysis.

  29944013   Complex role of IL-23R polymorphisms on ankylosing spondylitis: a meta-analysis.

  30206443   Genetic polymorphism in psoriasis and its meaning for the treatment efficacy in the future.

  30322951   Association between cytokine gene polymorphisms and ankylosing spondylitis susceptibility: a systematic review and meta-analysis.

  30646942   Association between IL23R and ERAP1 polymorphisms and sacroiliac or spinal MRI inflammation in spondyloarthritis: DESIR cohort data.

  30924147   Are genetic variations in IL-21-IL-23R-IL-17A cytokine axis involved in a pathogenic pathway of rheumatoid arthritis? Bayesian hierarchical meta-analysis.

  30942097   Associations between IL-23R gene polymorphisms and the susceptibility of rheumatoid arthritis: a meta-analysis.

  31052430   Genetic Studies of Inflammatory Bowel Disease-Focusing on Asian Patients.

  31648514   Evaluation of interleukin-23 receptor (IL-23R) gene polymorphisms and serum IL-23 levels in patients with psoriasis.

  31701644   Association analysis of interleukin-23 receptor SNPs and SAPHO syndrome in Chinese people.

  32779262   A framework for pathway knowledge driven prioritization in genome-wide association studies.

  32984386   Personalizing Treatment in IBD: Hype or Reality in 2020? Can We Predict Response to Anti-TNF?

  33340282   TH17/IL23 cytokine gene polymorphisms in bullous pemphigoid.

  33383665   Apremilast Pharmacogenomics in Russian Patients with Moderate-to-Severe and Severe Psoriasis.

  33978821   IL-23R gene polymorphisms in rheumatoid arthritis.

  34127053   Clinical, laboratory, and genetic markers for the development or presence of psoriatic arthritis in psoriasis patients: a systematic review.

  34573380   Pharmacogenomics: An Update on Biologics and Small-Molecule Drugs in the Treatment of Psoriasis.

  35814239   The Inflammatory Factor SNP May Serve as a Promising Biomarker for Acitretin to Alleviate Secondary Failure of Response to TNF-a Monoclonal Antibodies in Psoriasis.