Normal allele: GG
Genetic variability in the fibrinogen-gamma FGG gene increases the risk of deep vein thrombosis by reducing plasma fibrinogen-gamma levels.
Polymorphism rs2066865 is related to topics like this:
Research and publications:
17445871 The fibrinogen gamma (FGG) 10034C>T polymorphism is associated with venous thrombosis.
20709368 The fibrinogen gamma 10034C>T polymorphism is not associated with Peripheral Arterial Disease.
21422408 Clotting factor gene polymorphisms and colorectal cancer risk.
21757653 Assessing genetic determinants of the association of β-fibrinogen with cardiovascular disease.
21980494 Genetics of venous thrombosis: insights from a new genome wide association study.
22707612 Genetic risk factors for thrombosis in systemic lupus erythematosus.
25341889 Multilocus genetic risk scores for venous thromboembolism risk assessment.
25613928 Contribution of genetic and environmental factors to changes in total and β-fibrinogen over 5 years.
26423325 F11 is associated with recurrent VTE in women. A prospective cohort study.
27766050 Causes of venous thrombosis.
29995659 Venous thromboembolism risk associated with ABO, F11 and FGG loci.
31582554 Fibrinogen gamma gene rs2066865 and risk of cancer-related venous thromboembolism.
32110755 Myocardial infarction, prothrombotic genotypes, and venous thrombosis risk: The Tromsø Study.
32402998 Prothrombotic genotypes and risk of major bleeding in patients with incident venous thromboembolism.
34200207 Genetic Risk Profiling Associated with Recurrent Unprovoked Venous Thromboembolism.
34784644 The Risk of Venous Thromboembolism Attributed to Established Prothrombotic Genotypes.