SNP information rs1979277

Research and publications:

  15911586   Effects of natural selection on interpopulation divergence at polymorphic sites in human protein-coding Loci.

  17035141   Neural tube defects and folate pathway genes: family-based association tests of gene-gene and gene-environment interactions

  17119116   Gene-nutrient interactions among determinants of folate and one-carbon metabolism on the risk of non-Hodgkin lymphoma: NCI-SEER case-control study

  17366837   Genetic studies of a cluster of acute lymphoblastic leukemia cases in Churchill County, Nevada

  17420066   Polymorphisms of cytosolic serine hydroxymethyltransferase and risk of lung cancer: a case-control analysis.

  18381459   Genetic variation in the one-carbon transfer pathway and ovarian cancer risk.

  18521744   BRCA1 promoter methylation is associated with increased mortality among women with breast cancer

  18708404   B-vitamin intake, one-carbon metabolism, and survival in a population-based study of women with breast cancer

  18830263   Polymorphisms in DNA repair and one-carbon metabolism genes and overall survival in diffuse large B-cell lymphoma and follicular lymphoma

  19064578   No association of single nucleotide polymorphisms in one-carbon metabolism genes with prostate cancer risk

  19376481   One-carbon metabolism and breast cancer: an epidemiological perspective

  19706844   Association of folate-pathway gene polymorphisms with the risk of prostate cancer: a population-based nested case-control study, systematic review, and meta-analysis

  19776626   Polymorphisms in methionine synthase, methionine synthase reductase and serine hydroxymethyltransferase, folate and alcohol intake, and colon cancer risk

  20101025   Genetic variation in the folate metabolic pathway and risk of childhood leukemia

  20111745   Gene-gene interactions in the folate metabolic pathway and the risk of conotruncal heart defects

  20458436   Early-onset ischaemic stroke: analysis of 58 polymorphisms in 17 genes involved in methionine metabolism.

  20544798   Genetic and lifestyle variables associated with homocysteine concentrations and the distribution of folate derivatives in healthy premenopausal women

  20600216   Individual differences in arsenic metabolism and lung cancer in a case-control study in Cordoba, Argentina

  20670920   Association of genetic variation in cystathionine-beta-synthase and arsenic metabolism

  20852008   Associations of folate, vitamin B12, homocysteine, and folate-pathway polymorphisms with prostate-specific antigen velocity in men with localized prostate cancer.

  21146954   Genes and abdominal aortic aneurysm

  21178087   Polymorphisms in serine hydroxymethyltransferase 1 and methylenetetrahydrofolate reductase interact to increase cardiovascular disease risk in humans.

  21274745   Variation in folate pathway genes and distal colorectal adenoma risk: a sigmoidoscopy-based case-control study.

  21467728   Profile of participants and genotype distributions of 108 polymorphisms in a cross-sectional study of associations of genotypes with lifestyle and clinical factors: a project in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study.

  21615938   Genetic polymorphisms in folate pathway enzymes, DRD4 and GSTM1 are related to temporomandibular disorder.

  21618410   Folate pathway polymorphisms predict deficits in attention and processing speed after childhood leukemia therapy.

  21687976   Polymorphism C1420T of Serine hydroxymethyltransferase gene on maternal risk for Down syndrome.

  21747588   Genetic variation in genes involved in folate and drug metabolism in a south Indian population.

  21748308   Genetic variants in the folate pathway and risk of childhood acute lymphoblastic leukemia.

  21857689   Folate and vitamin B12 in idiopathic male infertility.

  22103680   Folate network genetic variation, plasma homocysteine, and global genomic methylation content: a genetic association study.

  22116453   Folate and vitamin B12-related genes and risk for omphalocele.

  22220685   Serine hydroxymethyltransferase 1 and 2: gene sequence variation and functional genomic characterization.

  22371529   DNA methylation in peripheral blood measured by LUMA is associated with breast cancer in a population-based study.

  22479380   Genetic and non-genetic influences during pregnancy on infant global and site specific DNA methylation: role for folate gene variants and vitamin B12.

  22496743   Genetic variant of AMD1 is associated with obesity in urban Indian children.

  22616673   Global tests of P-values for multifactor dimensionality reduction models in selection of optimal number of target genes.

  23294634   Risk score modeling of multiple gene to gene interactions using aggregated-multifactor dimensionality reduction.

  23401104   Folate-genetics and colorectal neoplasia: what we know and need to know next.

  23446900   One-carbon metabolism factors and leukocyte telomere length.

  23913011   Role of one-carbon metabolizing pathway genes and gene-nutrient interaction in the risk of non-Hodgkin lymphoma.

  23940529   Roles of genetic polymorphisms in the folate pathway in childhood acute lymphoblastic leukemia evaluated by Bayesian relevance and effect size analysis.

  24048206   Neural tube defects, folic acid and methylation.

  24362509   DNMT3B C46359T and SHMT1 C1420T polymorphisms in the folate pathway in carcinogenesis of head and neck.

  24524080   The effect of multiple single nucleotide polymorphisms in the folic acid pathway genes on homocysteine metabolism.

  25041994   Polymorphisms in folate-metabolizing enzymes and response to 5-fluorouracil among patients with stage II or III rectal cancer (INT-0144; SWOG 9304).

  25227144   Folate-related polymorphisms in gastrointestinal stromal tumours: susceptibility and correlation with tumour characteristics and clinical outcome.

  27808252   Functional variants of the 5-methyltetrahydrofolate-homocysteine methyltransferase gene significantly increase susceptibility to prostate cancer: Results from an ethnic Han Chinese population.

  29627528   The association between donor genetic variations in one-carbon metabolism pathway genes and hepatitis B recurrence after liver transplantation.

  29953918   Identification of three novel loci of ALDH2 Gene for Serum Folate levels in a Male Chinese Population by Genome-Wide Association Study.

  30456721   Association of SHMT1, MAZ, ERG, and L3MBTL3 Gene Polymorphisms with Susceptibility to Multiple Sclerosis.

  30587867   Polymorphisms in folic acid metabolism genes do not associate with cancer cachexia in Japanese gastrointestinal patients.

  31713293   A SHMT1 variant decreases the risk of nonsyndromic cleft lip with or without cleft palate in Chile.

  33369477   Gene Polymorphisms Involved in Folate Metabolism and DNA Methylation with the Risk of Head and Neck Cancer.

  33974584   Association Between SHMT1 rs1979277 Polymorphism and Risk of Acute Lymphoblastic Leukemia: A Systematic Review and Meta-analysis.

  34013078   Host pharmacogenetic factors that may affect liver neoplasm incidence upon using direct-acting antivirals for treating hepatitis C infection.

  35098008   Maternal polymorphic loci of rs1979277 serine hydroxymethyl transferase and rs1805087 5-methylenetetrahydrofolate are correlated with the development of fetal growth restriction: A case-control study.