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SNP information rs182549

Normal allele: TT

Is one of two SNPs linked to the primary haplotype associated with hypolactasia, more commonly known as lactose intolerance in European populations.

Polymorphism rs182549 is related to topics like this:


Research and publications:

  11788828   Identification of a variant associated with adult-type hypolactasia.

  15114531   Genetic signatures of strong recent positive selection at the lactase gene.

  18974842   Gender differences in genetic risk profiles for cardiovascular disease

  19326473   Natriuretic peptide system gene variants are associated with ventricular dysfunction after coronary artery bypass grafting.

  19668368   Ancestry analysis in the 11-M Madrid bomb attack investigation.

  20031626   Variation in the 4q25 chromosomal locus predicts atrial fibrillation after coronary artery bypass graft surgery.

  21212231   A hierarchical Bayesian model for next-generation population genomics.

  22228373   Polymorphism in the protease-activated receptor-4 gene region associates with platelet activation and perioperative myocardial injury.

  22332091   Recent advances in understanding the role of nutrition in human genome evolution.

  23028602   Lactase persistence and lipid pathway selection in the Maasai.

  23029545   Several different lactase persistence associated alleles and high diversity of the lactase gene in the admixed Brazilian population.

  26988143   Human adaptation and population differentiation in the light of ancient genomes.

  27170764   Association of lactase persistence genotype with milk consumption, obesity and blood pressure: a Mendelian randomization study in the 1982 Pelotas (Brazil) Birth Cohort, with a systematic review and meta-analysis.

  30339693   Association between functional lactase variants and a high abundance of Bifidobacterium in the gut of healthy Japanese people.

  31352438   Genetic and Oral Tests for the Diagnosis of Lactose Intolerance in Mixed-Ancestry Brazilians with Metabolic Syndrome.

  33170161   Genetic test for the prescription of diets in support of physical activity.

  33261611   Genetically proxied milk consumption and risk of colorectal, bladder, breast, and prostate cancer: a two-sample Mendelian randomization study.

  34159422   Host genetic control of gut microbiome composition.