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SNP information rs1799724

RS1799724

Normal allele: CC

Polymorphism rs1799724 of the tumour necrosis factor alpha gene in Alzheimer's disease.

Polymorphism rs1799724 is related to topics like this:

Dementia is genetic

Dementia is characterized as a syndrome, rather than a singular disease. Individuals with early...

Alzheimer's disease is hereditary

Alzheimer's disease is a degenerative brain disease that causes dementia, resulting in a gradual...


Research and publications:

  11273064   Association between polymorphisms in the regulatory region of the gene encoding tumor necrosis factor alpha and the risk of Alzheimer's disease and vascular dementia: a case-control study.

  12509789   Identification of I kappa BL as the second major histocompatibility complex-linked susceptibility locus for rheumatoid arthritis.

  15895461   TNF polymorphisms in Alzheimer disease and functional implications on CSF beta-amyloid levels

  16449530   Cytokine polymorphisms in the Th1/Th2 pathway and susceptibility to non-Hodgkin lymphoma

  16916584   Interleukin-1 alpha and beta, TNF-alpha and HTTLPR gene variants study on alcohol toxicity and detoxification outcome.

  17018637   Common genetic variants in proinflammatory and other immunoregulatory genes and risk for non-Hodgkin lymphoma

  17062130   Polymorphisms within inflammatory genes and colorectal cancer.

  17327408   Prognostic significance of host immune gene polymorphisms in follicular lymphoma survival

  17355643   Frequencies of single nucleotide polymorphisms in genes regulating inflammatory responses in a community-based population

  17450233   Parental smoking modifies the relation between genetic variation in tumor necrosis factor-alpha (TNF) and childhood asthma

  17493155   Significant association between TNF-alpha (TNF) promoter allele (-1031C, -863C, and -857C) and cerebral malaria in Thailand.

  18196539   TNF polymorphisms and prostate cancer risk

  18319718   Tumour-necrosis factor-A polymorphisms and gastric cancer risk: a meta-analysis

  18366708   SNP selection for genes of iron metabolism in a study of genetic modifiers of hemochromatosis.

  18551993   SNP combinations in chromosome-wide genes are associated with bone mineral density in Taiwanese women

  18603647   Functional genetic polymorphisms and female reproductive disorders: Part I: Polycystic ovary syndrome and ovarian response

  18633131   Host immune gene polymorphisms in combination with clinical and demographic factors predict late survival in diffuse large B-cell lymphoma patients in the pre-rituximab era

  18635873   TNF promoter polymorphisms associated with muscle phenotypes in humans

  18676870   Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China

  18698679   Single nucleotide polymorphism in the tumor necrosis factor-alpha gene affects inflammatory bowel diseases risk

  18709160   Interactions between glutathione S-transferase P1, tumor necrosis factor, and traffic-related air pollution for development of childhood allergic disease

  18805939   Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis

  18811622   Association of TNF-alpha with severe respiratory syncytial virus infection and bronchial asthma

  18990758   Genetic variation in tumor necrosis factor and canonical nuclear factor-kappaB pathway and risk of non-Hodgkin's lymphoma

  19066394   Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma

  19282863   Association of candidate gene polymorphisms with chronic kidney disease in Japanese individuals with hypertension.

  19406964   Association of genetic variants with chronic kidney disease in Japanese individuals.

  19505919   Toll-like receptor signaling pathway variants and prostate cancer mortality

  19615068   The role of TNF genetic variants and the interaction with cigarette smoking for gastric cancer risk: a nested case-control study

  19673019   IL-10 and TNF-alpha promoter haplotypes are associated with the location of Crohn's disease in children

  19673882   A novel association between a SNP in CYBRD1 and serum ferritin levels in a cohort study of HFE hereditary haemochromatosis.

  19742166   Epistasis between IL1A, IL1B, TNF, HTR2A, 5-HTTLPR and TPH2 variations does not impact alcohol dependence disorder features.

  19773451   Role of inflammation gene polymorphisms on pain severity in lung cancer patients

  19818126   Single nucleotide polymorphisms in obesity-related genes and all-cause and cause-specific mortality: a prospective cohort study

  19933216   The COPD genetic association compendium: a comprehensive online database of COPD genetic associations

  20112337   Single nucleotide polymorphisms of 8 inflammation-related genes and their associations with smoking-related cancers

  20357201   Association of polymorphisms of tumor necrosis factor and tumor protein p53 with primary open-angle glaucoma.

  20473875   Association of haplotypes of inflammation-related genes with gastric preneoplastic lesions in African Americans and Caucasians

  20668555   Extended LTA, TNF, LST1 and HLA gene haplotypes and their association with rubella vaccine-induced immunity.

  20711808   Polymorphisms in oxidative stress and inflammation pathway genes, low-dose ionizing radiation, and the risk of breast cancer among US radiologic technologists

  20811626   Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer

  20846217   Association of linear growth impairment in pediatric Crohn's disease and known growth locus: a pilot study.

  20952689   Cytokine polymorphisms in Th1/Th2 pathway genes, body mass index, and risk of non-Hodgkin lymphoma

  21029472   A study of the TNF/LTA/LTB locus and susceptibility to severe malaria in highland papuan children and adults.

  21149504   Common variations in genes encoding C-reactive protein, tumor necrosis factor-alpha, and interleukin-6 and risk of clinical diabetes in the Women's Health Initiative observational study.

  21160888   Genetic predisposition to Helicobacter pylori-induced gastric precancerous conditions

  21228795   Impact of LIMK1, MMP2 and TNF-α variations for intracranial aneurysm in Japanese population.

  21333900   The role of genetics in IBS

  21385363   Polymorphisms in genes controlling inflammation and tissue repair in rheumatoid arthritis: a case control study

  21393601   Carotid plaque and candidate genes related to inflammation and endothelial function in Hispanics from northern Manhattan.

  21467728   Profile of participants and genotype distributions of 108 polymorphisms in a cross-sectional study of associations of genotypes with lifestyle and clinical factors: a project in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study.

  21509504   Interleukin-1α, interleukin-1β and tumor necrosis factor-α genetic variants and risk of dementia in the very old: evidence from the "Monzino 80-plus" prospective study.

  21523452   Genetic variation in proinflammatory cytokines IL6, IL6R, TNF-region, and TNFRSF1A and risk of breast cancer.

  21708280   Candidate gene studies in gallbladder cancer: a systematic review and meta-analysis

  21776368   Association of TNF-857C>T, TNFRSF1A36A>G, and TNFRSF1B676T>G Polymorphisms with Ischemic Stroke in a Greek Population.

  21818296   The TNF-alpha-238 polymorphism and cancer risk: a meta-analysis.

  21875636   Associations between single nucleotide polymorphisms and haplotypes in cytokine and cytokine receptor genes and immunity to measles vaccination.

  21904873   Association of tumor necrosis factor-α (TNF-α) promoter polymorphisms with overweight/obesity in a Korean population.

  21985478   TNFA-863 polymorphism is associated with a reduced risk of chronic obstructive pulmonary disease: a replication study.

  22001640   Tumour necrosis factor gene polymorphisms and migraine: a systematic review and meta-analysis.

  22180854   Polymorphisms in Th1/Th2 cytokine genes, hormone replacement therapy, and risk of non-Hodgkin lymphoma.

  22190997   Characterization of Single-Nucleotide Polymorphisms in the Tumor Necrosis Factor α Promoter Region and in Lymphotoxin α in Squamous Intraepithelial Lesions, Precursors of Cervical Cancer.

  22230215   Pro-/anti-inflammatory cytokine gene polymorphisms and chronic kidney disease: a cross-sectional study.

  22487520   TNF-alpha gene (TNFA) variants increase risk for multi-organ dysfunction syndrome (MODS) in acute pancreatitis.

  22630053   Immune regulatory gene polymorphisms as predisposing risk factors for the development of factor VIII inhibitors in Indian severe haemophilia A patients.

  22711844   SNP in the TNF-α gene promoter associated with Behçet's disease in Moroccan patients.

  22911757   Association study of candidate gene polymorphisms with amnestic mild cognitive impairment in a Chinese population.

  22947458   Malaria resistance genes are associated with the levels of IgG subclasses directed against Plasmodium falciparum blood-stage antigens in Burkina Faso.

  23021043   Genetics of Bechsche's disease in Sardinia: two different expanded HLA haplotypes carry the B*51 allele in the normal population and in patients.

  23029405   Genetic variation in the TNF gene is associated with susceptibility to severe sepsis, but not with mortality.

  23049851   Potential of ayurgenomics approach in complex trait research: leads from a pilot study on rheumatoid arthritis.

  23050663   Polymorphism of tumor necrosis factor alpha (TNF-alpha) gene promoter, circulating TNF-alpha level, and cardiovascular risk factor for ischemic stroke.

  23057767   Inflammatory gene variants and the risk of biliary tract cancers and stones: a population-based study in China.

  23071570   Gene-gene interaction and functional impact of polymorphisms on innate immune genes in controlling Plasmodium falciparum blood infection level.

  23086128   Profiles of gene polymorphisms in cytokines and Toll-like receptors with higher risk for gastric cancer.

  23217179   IL1B, IL4R, IL12RB1 and TNF gene polymorphisms are associated with Plasmodium vivax malaria in Brazil.

  23316245   The host genetic diversity in malaria infection.

  24069534   Genetics of psoriasis and pharmacogenetics of biological drugs.

  24139238   Genetic polymorphisms involved in the inflammatory response and lung cancer risk: a case-control study in Japan.

  24151497   Analysis of the association of IL10, TNF-β and IL23R-IL12RB2 SNPs with the risk of Behçet's disease in Western Algeria.

  24259423   Genetic variation in the lymphotoxin-α (LTA)/tumour necrosis factor-α (TNFα) locus as a risk factor for idiopathic achalasia.

  24281113   Inflammatory genetic markers of prostate cancer risk.

  24491308   Systematic review and meta-analysis of candidate gene association studies of lower urinary tract symptoms in men.

  24936650   Association between tumor necrosis factor-α rs1800629 polymorphism and risk of asthma: a meta-analysis.

  24967817   Anti-TNF treatment response in rheumatoid arthritis patients is associated with genetic variation in the NLRP3-inflammasome.

  24971461   Polymorphisms in the inflammatory pathway genes TLR2, TLR4, TLR9, LY96, NFKBIA, NFKB1, TNFA, TNFRSF1A, IL6R, IL10, IL23R, PTPN22, and PPARG are associated with susceptibility of inflammatory bowel disease in a Danish cohort.

  25083576   Tumor necrosis factor-alpha and polycystic ovarian syndrome: a clinical, biochemical, and molecular genetic study.

  25606441   In silico analysis of single nucleotide polymorphism (SNP) in human TNF-α gene.

  25636570   Association of TNF -1031 C/C as a potential protection marker for leprosy development in Amazonas state patients, Brazil.

  25731870   Genetic variation and gastric cancer risk: a field synopsis and meta-analysis.

  26088449   Influence of functional polymorphisms in TNF-α, IL-8, and IL-10 cytokine genes on mRNA expression levels and risk of gastric cancer.

  26088606   Tumour necrosis factor allele variants and their association with the occurrence and severity of malaria in African children: a longitudinal study.

  26418997   [Association of TNF-alpha and IL-13 genes polymorphisms with bronchial asthma].

  26572151   Polymorphisms of tumor necrosis factor alpha in Middle Eastern population with colorectal cancer.

  26601827   The IL-1B Genetic Polymorphism Is Associated with Aspirin-Induced PepticUlcers in a Korean Ethnic Group.

  26646537   TNF-α and MTHFR Polymorphisms Associated with Cerebral Palsy in Chinese Infants.

  26672513   Association between hepatocellular carcinoma and tumor necrosis factor alpha polymorphisms in South Korea.

  26751459   Association between CRP and TNF-α genes Variants and Cardiovascular Heart Disease in a Mexican Population: Protocol for a Case-Control Study.

  26861312   Association between Genetic Polymorphisms and Response to Anti-TNFs in Patients with Inflammatory Bowel Disease.

  26870349   Impact of single-nucleotide polymorphisms on radiation pneumonitis in cancer patients.

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