SNP information rs17708472

Research and publications:

  16270629   VKORC1 haplotypes and their impact on the inter-individual and inter-ethnical variability of oral anticoagulation.

  16611750   Polymorphisms in the VKORC1 gene are strongly associated with warfarin dosage requirements in patients receiving anticoagulation.

  18252229   Warfarin pharmacogenetics: CYP2C9 and VKORC1 genotypes predict different sensitivity and resistance frequencies in the Ashkenazi and Sephardi Jewish populations.

  18855533   VKORC1 polymorphisms, haplotypes and haplotype groups on warfarin dose among African-Americans and European-Americans.

  19436136   Association of sequence variations in vitamin K epoxide reductase and gamma-glutamyl carboxylase genes with biochemical measures of vitamin K status.

  20128861   Comparative performance of gene-based warfarin dosing algorithms in a multiethnic population.

  20716240   New genetic variant that might improve warfarin dose prediction in African Americans.

  21127708   Genetic variation of VKORC1 and CYP4F2 genes related to warfarin maintenance dose in patients with myocardial infarction.

  21628633   Circulating uncarboxylated matrix gla protein is associated with vitamin K nutritional status, but not coronary artery calcium, in older adults.

  22118051   Genetic variants in CYP (-1A2, -2C9, -2C19, -3A4 and -3A5), VKORC1 and ABCB1 genes in a black South African population: a window into diversity.

  22676192   Retrospective evidence for clinical validity of expanded genetic model in warfarin dose optimization in a South Indian population.

  22952875   Influence of CYP2C9 and VKORC1 on patient response to warfarin: a systematic review and meta-analysis.

  22992668   Pharmacogenomics knowledge for personalized medicine.

  24944790   Screening for 392 polymorphisms in 141 pharmacogenes.

  25084205   Methodological issues in the development of a pharmacogenomic algorithm for warfarin dosing: comparison of two regression approaches.

  26444257   Genetic diversity of variants involved in drug response and metabolism in Sri Lankan populations: implications for clinical implementation of pharmacogenomics.

  26858644   Cross-Comparison of Exome Analysis, Next-Generation Sequencing of Amplicons, and the iPLEX(®) ADME PGx Panel for Pharmacogenomic Profiling.

  30486437   Impact of CYP2C9 and VKORC1 Polymorphisms on Warfarin Sensitivity and Responsiveness in Jordanian Cardiovascular Patients during the Initiation Therapy.

  31061616   Effects of CYP2C9 and VKORC1 polymorphisms on warfarin sensitivity and responsiveness during the stabilization phase of therapy.

  31114289   VKORC1 variants as significant predictors of warfarin dose in Emiratis.

  32326111   Role of Genetic Variations in the Hepatic Handling of Drugs.

  32380173   Recommendations for Clinical Warfarin Genotyping Allele Selection: A Report of the Association for Molecular Pathology and the College of American Pathologists.

  33519226   Genetic Diversity of Drug-Related Genes in Native Americans of the Brazilian Amazon.

  34621706   Comprehensive analysis of important pharmacogenes in Koreans using the DMET™ platform.

  34824904   Genetic diversity of "highly important pharmacogenes" in two South Asian populations.

  34958284   Warfarin Pharmacogenomics for Precision Medicine in Real-Life Clinical Practice in Southern Africa: Harnessing 73 Variants in 29 Pharmacogenes.

  35337356   Cross-ethnic analysis of common gene variants in hemostasis show lopsided representation of global populations in genetic databases.