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SNP information rs1412444

RS1412444

Normal allele: CC

A single nucleotide polymorphism in the LIPA (lysosomal acidic lipase A) gene is associated with predisposition to premature coronary heart disease.

Polymorphism rs1412444 is related to topics like this:

Heart attack genetic

Genetic predisposition, also referred to as familial predisposition, is a crucial risk factor for...

Heart disease genetic

Although genetics can be a major factor in the development of certain heart diseases, individuals...


Research and publications:

  21606135   A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease.

  21846871   A genome-wide association study in europeans and South asians identifies 5 new Loci for coronary artery disease.

  21875899   Thirty-five common variants for coronary artery disease: the fruits of much collaborative labour.

  22588700   Genetics of coronary artery disease in the 21st century.

  23468967   Improvement in prediction of coronary heart disease risk over conventional risk factors using SNPs identified in genome-wide association studies.

  24475106   Genetic variants associated with myocardial infarction and the risk factors in Chinese population.

  24932356   Genetics of coronary artery disease: an update.

  24991929   Association of common genetic variants with lipid traits in the Indian population.

  25542012   Prospective associations of coronary heart disease loci in African Americans using the MetaboChip: the PAGE study.

  26847647   Experimental Biology for the Identification of Causal Pathways in Atherosclerosis.

  26892960   From Loci to Biology: Functional Genomics of Genome-Wide Association for Coronary Disease.

  26958643   Detailed analysis of association between common single nucleotide polymorphisms and subclinical atherosclerosis: The Multi-ethnic Study of Atherosclerosis.

  27189168   The impact of genome-wide association studies on the pathophysiology and therapy of cardiovascular disease.

  27294088   Genetics of the acute coronary syndrome.

  27424552   Genomics era and complex disorders: Implications of GWAS with special reference to coronary artery disease, type 2 diabetes mellitus, and cancers.

  27827461   Association and interaction of APOA5, BUD13, CETP, LIPA and health-related behavior with metabolic syndrome in a Taiwanese population.

  28426714   A genetic risk score for CAD, psychological stress, and their interaction as predictors of CAD, fatal MI, non-fatal MI and cardiovascular death.

  28577571   Genetic determinants of inherited susceptibility to hypercholesterolemia - a comprehensive literature review.

  28686695   Coronary artery disease-associated genetic variants and biomarkers of inflammation.

  29695241   Novel risk genes identified in a genome-wide association study for coronary artery disease in patients with type 1 diabetes.

  31845553   Precision Medicine and Cardiovascular Health: Insights from Mendelian Randomization Analyses.

  35124268   Mendelian Randomization Analysis Reveals No Causal Relationship Between Nonalcoholic Fatty Liver Disease and Severe COVID-19.

  35192625   Interpreting coronary artery disease GWAS results: A functional genomics approach assessing biological significance.

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