Normal allele: CC
A single nucleotide polymorphism in the LIPA (lysosomal acidic lipase A) gene is associated with predisposition to premature coronary heart disease.
Polymorphism rs1412444 is related to topics like this:
Research and publications:
21875899 Thirty-five common variants for coronary artery disease: the fruits of much collaborative labour.
22588700 Genetics of coronary artery disease in the 21st century.
24475106 Genetic variants associated with myocardial infarction and the risk factors in Chinese population.
24932356 Genetics of coronary artery disease: an update.
24991929 Association of common genetic variants with lipid traits in the Indian population.
26847647 Experimental Biology for the Identification of Causal Pathways in Atherosclerosis.
26892960 From Loci to Biology: Functional Genomics of Genome-Wide Association for Coronary Disease.
27294088 Genetics of the acute coronary syndrome.
28686695 Coronary artery disease-associated genetic variants and biomarkers of inflammation.
31845553 Precision Medicine and Cardiovascular Health: Insights from Mendelian Randomization Analyses.